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There is increasing interest in allocating treatments based on observed individual characteristics: examples include targeted marketing, individualized credit offers, and heterogeneous pricing. Treatment personalization introduces…

计量经济学 · 经济学 2023-04-06 Evan Munro

Clinical diagnosis prediction models, when provided with a patient's medical history, aim to detect potential diseases early, facilitating timely intervention and improving prognostic outcomes. However, the inherent scarcity of patient data…

计算与语言 · 计算机科学 2025-01-30 Mingyu Derek Ma , Xiaoxuan Wang , Yijia Xiao , Anthony Cuturrufo , Vijay S Nori , Eran Halperin , Wei Wang

A key aspect of patient-focused drug development is identifying and measuring outcomes that are important to patients in clinical trials. Many medical conditions affect multiple symptom domains, and a consensus approach to determine the…

统计方法学 · 统计学 2025-10-14 David S. Robertson , Thomas Jaki

As the demand for more personalized recommendation grows and a dramatic boom in commercial scenarios arises, the study on multi-scenario recommendation (MSR) has attracted much attention, which uses the data from all scenarios to…

信息检索 · 计算机科学 2025-08-26 Yuhao Wang , Yichao Wang , Zichuan Fu , Xiangyang Li , Xiangyu Zhao , Huifeng Guo , Ruiming Tang

Patients who are seriously ill may ask doctors to treat them with unapproved medication, about which not much is known, or else with known medication in a high dosage. Apart from strict legal constraints such cases may involve difficult…

其他统计学 · 统计学 2018-04-13 F. Thomas Bruss

Medical triage is the task of allocating medical resources and prioritizing patients based on medical need. This paper introduces the first large-scale public dataset for studying medical triage in the context of asynchronous outpatient…

计算与语言 · 计算机科学 2026-01-21 Joseph Gatto , Parker Seegmiller , Timothy Burdick , Philip Resnik , Roshnik Rahat , Sarah DeLozier , Sarah M. Preum

Information retrieval (IR) for precision medicine (PM) often involves looking for multiple pieces of evidence that characterize a patient case. This typically includes at least the name of a condition and a genetic variation that applies to…

计算与语言 · 计算机科学 2020-12-18 Jiho Noh , Ramakanth Kavuluru

Psychiatric intake is a sequential, high-stakes information-gathering process in which clinicians must decide what to ask, in what order, and how to interpret incomplete or ambiguous responses under limited time. Despite growing interest in…

计算与语言 · 计算机科学 2026-04-29 Guan Gui , Peter Zandi , Jacob Taylor , Ananya Joshi

Medical AI, including clinical language models, vision-language models, and multimodal health record models, already summarizes notes, answers questions, and supports decisions. Their adaptation to new populations, specialties, or care…

Because many illnesses show heterogeneous response to treatment, there is increasing interest in individualizing treatment to patients [Arch. Gen. Psychiatry 66 (2009) 128--133]. An individualized treatment rule is a decision rule that…

统计理论 · 数学 2011-05-18 Min Qian , Susan A. Murphy

Comparing outcomes across treatments is essential in medicine and public policy. To do so, researchers typically estimate a set of parameters, possibly counterfactual, with each targeting a different treatment. Treatment-specific means are…

统计方法学 · 统计学 2025-10-07 Alec McClean , Yiting Li , Sunjae Bae , Mara A. McAdams-DeMarco , Iván Díaz , Wenbo Wu

Personalized cancer treatment requires a thorough understanding of complex interactions between drugs and cancer cell lines in varying genetic and molecular contexts. To address this, high-throughput screening has been used to generate…

机器学习 · 计算机科学 2023-07-03 Vishal Dey , Xia Ning

In many real world problems, we are faced with the problem of selecting the best among a finite number of alternatives, where the best alternative is determined based on context specific information. In this work, we study the contextual…

最优化与控制 · 数学 2022-01-20 Sait Cakmak , Siyang Gao , Enlu Zhou

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

统计方法学 · 统计学 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

This paper proposes a novel criterion for the allocation of patients in Phase~I dose-escalation clinical trials aiming to find the maximum tolerated dose (MTD). Conventionally, using a model-based approach the next patient is allocated to…

统计方法学 · 统计学 2018-07-17 Pavel Mozgunov , Thomas Jaki

The explorations of models beyond the Standard Model (BSM) naturally involve scans over the unknown BSM parameters. On the other hand, high precision predictions require calculations at the loop-level and thus a renormalization of (some of)…

高能物理 - 唯象学 · 物理学 2024-07-01 S. Heinemeyer , F. von der Pahlen

An overview of current debates and contemporary research devoted to the modeling of decision making processes and their facilitation directs attention to the Analytic Hierarchy Process (AHP). At the core of the AHP are various…

人工智能 · 计算机科学 2020-06-05 Paul Thaddeus Kazibudzki

Medical question answering requires advanced reasoning that integrates domain knowledge with logical inference. However, existing large language models (LLMs) often generate reasoning chains that lack factual accuracy and clinical…

计算与语言 · 计算机科学 2025-12-09 Chia-Hsuan Hsu , Jun-En Ding , Hsin-Ling Hsu , Chih-Ho Hsu , Li-Hung Yao , Chun-Chieh Liao , Feng Liu , Fang-Ming Hung

The performance of Emergency Departments (EDs) is of great importance for any health care system, as they serve as the entry point for many patients. However, among other factors, the variability of patient acuity levels and corresponding…

机器学习 · 计算机科学 2022-06-09 Nikolaus Furian , Michael O'Sullivan , Cameron Walker , Melanie Reuter-Oppermann

With an ever growing number of heterogeneous applicational services running on equally heterogeneous computational systems, the problem of resource management becomes more essential. Although current solutions consider some network and time…

分布式、并行与集群计算 · 计算机科学 2025-08-05 Rui Eduardo Lopes , Duarte Raposo , Pedro V. Teixeira , Susana Sargento