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Multi-modal biological, imaging, and neuropsychological markers have demonstrated promising performance for distinguishing Alzheimer's disease (AD) patients from cognitively normal elders. However, it remains difficult to early predict when…

计算机视觉与模式识别 · 计算机科学 2019-01-08 Hongming Li , Yong Fan

In a missing-data setting, we have a sample in which a vector of explanatory variables x_i is observed for every subject i, while scalar outcomes y_i are missing by happenstance on some individuals. In this work we propose robust estimates…

统计理论 · 数学 2010-09-20 Mariela Sued , Victor J. Yohai

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

图像与视频处理 · 电气工程与系统科学 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

Functional data analysis is a fast evolving branch of statistics. Estimation procedures for the popular functional linear model either suffer from lack of robustness or are computationally burdensome. To address these shortcomings, a…

统计方法学 · 统计学 2021-08-27 Ioannis Kalogridis , Stefan Van Aelst

We introduce and study a family of robust estimators for the functional logistic regression model whose robustness automatically adapts to the data thereby leading to estimators with high efficiency in clean data and a high degree of…

统计方法学 · 统计学 2023-05-03 Ioannis Kalogridis

We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image…

计算机视觉与模式识别 · 计算机科学 2018-07-09 Chengliang Yang , Anand Rangarajan , Sanjay Ranka

Recently, deep learning has been widely applied in functional data analysis (FDA) with notable empirical success. However, the infinite dimensionality of functional data necessitates an effective dimension reduction approach for functional…

机器学习 · 统计学 2025-05-13 Zhongjie Shi , Jun Fan , Linhao Song , Ding-Xuan Zhou , Johan A. K. Suykens

Early detection of Alzheimer disease is crucial for deploying interventions and slowing the disease progression. A lot of machine learning and deep learning algorithms have been explored in the past decade with the aim of building an…

图像与视频处理 · 电气工程与系统科学 2022-09-26 Narotam Singh , Patteshwari. D , Neha Soni , Amita Kapoor

Estimating location is a central problem in functional data analysis, yet most current estimation procedures either unrealistically assume completely observed trajectories or lack robustness with respect to the many kinds of anomalies one…

统计方法学 · 统计学 2022-03-24 Ioannis Kalogridis , Stefan Van Aelst

In this paper, we focus on fully connected deep neural networks utilizing the Rectified Linear Unit (ReLU) activation function for nonparametric estimation. We derive non-asymptotic bounds that lead to convergence rates, addressing both…

In this paper, we study the properties of robust nonparametric estimation using deep neural networks for regression models with heavy tailed error distributions. We establish the non-asymptotic error bounds for a class of robust…

统计理论 · 数学 2021-07-23 Guohao Shen , Yuling Jiao , Yuanyuan Lin , Jian Huang

Discriminating patients with Alzheimer's disease (AD) from healthy subjects is a crucial task in the research of Alzheimer's disease. The task can be potentially achieved by linear discriminant analysis (LDA), which is one of the most…

统计方法学 · 统计学 2020-05-05 Yingjie Li , Liangliang Zhang , Tapabrata Maiti

In this study, we establish that deep neural networks employing ReLU and ReLU$^2$ activation functions can effectively represent Lagrange finite element functions of any order on various simplicial meshes in arbitrary dimensions. We…

数值分析 · 数学 2024-01-15 Juncai He , Jinchao Xu

We study the expressive power of deep ReLU neural networks for approximating functions in dilated shift-invariant spaces, which are widely used in signal processing, image processing, communications and so on. Approximation error bounds are…

机器学习 · 计算机科学 2023-12-05 Yunfei Yang , Zhen Li , Yang Wang

This paper addresses the problem of providing robust estimators under a functional logistic regression model. Logistic regression is a popular tool in classification problems with two populations. As in functional linear regression,…

统计方法学 · 统计学 2023-08-16 Graciela Boente , Marina Valdora

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

计算机视觉与模式识别 · 计算机科学 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

We consider neural networks with rational activation functions. The choice of the nonlinear activation function in deep learning architectures is crucial and heavily impacts the performance of a neural network. We establish optimal bounds…

神经与进化计算 · 计算机科学 2020-10-01 Nicolas Boullé , Yuji Nakatsukasa , Alex Townsend

While deep neural networks are highly performant and successful in a wide range of real-world problems, estimating their predictive uncertainty remains a challenging task. To address this challenge, we propose and implement a loss function…

机器学习 · 计算机科学 2022-10-14 Tony Tohme , Kevin Vanslette , Kamal Youcef-Toumi

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

图像与视频处理 · 电气工程与系统科学 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Deep neural networks are increasingly being used to detect and diagnose medical conditions using medical imaging. Despite their utility, these models are highly vulnerable to adversarial attacks and distribution shifts, which can affect…

图像与视频处理 · 电气工程与系统科学 2025-06-23 Josué Martínez-Martínez , Olivia Brown , Mostafa Karami , Sheida Nabavi