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Suppose we are interested in the effect of a treatment in a clinical trial. The efficiency of inference may be limited due to small sample size. However, external control data are often available from historical studies. Motivated by an…

统计方法学 · 统计学 2021-12-10 Xinyu Li , Wang Miao , Fang Lu , Xiao-Hua Zhou

Pragmatic trials increasingly define outcomes using real-world data such as electronic health records, where assessments are collected during routine care rather than at fixed timepoints. Consequently, these uncontrolled assessments may be…

With the advancement of telemedicine, both researchers and medical practitioners are working hand-in-hand to develop various techniques to automate various medical operations, such as diagnosis report generation. In this paper, we first…

计算与语言 · 计算机科学 2023-09-28 Abhisek Tiwari , Anisha Saha , Sriparna Saha , Pushpak Bhattacharyya , Minakshi Dhar

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

机器学习 · 计算机科学 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

Information integration plays a pivotal role in biomedical studies by facilitating the combination and analysis of independent datasets from multiple studies, thereby uncovering valuable insights that might otherwise remain obscured due to…

统计方法学 · 统计学 2024-07-02 Chixiang Chen , Jia Liang , Elynn Chen , Ming Wang

The importance of uncertainty quantification is increasingly recognized in the diverse field of machine learning. Accurately assessing model prediction uncertainty can help provide deeper understanding and confidence for researchers and…

机器学习 · 计算机科学 2024-12-03 Tianyi Chen , Yingzhou Lu , Nan Hao , Yuanyuan Zhang , Capucine Van Rechem , Jintai Chen , Tianfan Fu

Text summarization in medicine can help doctors for reducing the time to access important information from countless documents. The paper offers a supervised extractive summarization method based on conditional generative adversarial…

计算与语言 · 计算机科学 2021-10-25 Seyed Vahid Moravvej , Abdolreza Mirzaei , Mehran Safayani

The impact of machine learning models on healthcare will depend on the degree of trust that healthcare professionals place in the predictions made by these models. In this paper, we present a method to provide people with clinical expertise…

机器学习 · 计算机科学 2021-03-05 Aniruddh Raghu , John Guttag , Katherine Young , Eugene Pomerantsev , Adrian V. Dalca , Collin M. Stultz

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic…

Meta-analysis is a systematic approach for understanding a phenomenon by analyzing the results of many previously published experimental studies. It is central to deriving conclusions about the summary effect of treatments and interventions…

计算机与社会 · 计算机科学 2021-04-13 Lu Cheng , Dmitriy A. Katz-Rogozhnikov , Kush R. Varshney , Ioana Baldini

A medical provider's summary of a patient visit serves several critical purposes, including clinical decision-making, facilitating hand-offs between providers, and as a reference for the patient. An effective summary is required to be…

计算与语言 · 计算机科学 2023-05-11 Varun Nair , Elliot Schumacher , Anitha Kannan

We propose a summarization approach for scientific articles which takes advantage of citation-context and the document discourse model. While citations have been previously used in generating scientific summaries, they lack the related…

计算与语言 · 计算机科学 2017-04-24 Arman Cohan , Nazli Goharian

The records of a clinical encounter can be extensive and complex, thus placing a premium on tools that can extract and summarize relevant information. This paper introduces the task of generating discharge summaries for a clinical…

计算与语言 · 计算机科学 2021-04-29 Han-Chin Shing , Chaitanya Shivade , Nima Pourdamghani , Feng Nan , Philip Resnik , Douglas Oard , Parminder Bhatia

The focus of this paper is on quantifying the capacity of covariates in devising efficient treatment rules when data from a randomized trial are available. Conventional one-variable-at-a-time subgroup analysis based on statistical…

应用统计 · 统计学 2020-02-04 Mohsen Sadatsafavi , Mohammad Mansournia , Paul Gustafson

We introduce Trialstreamer, a living database of clinical trial reports. Here we mainly describe the evidence extraction component; this extracts from biomedical abstracts key pieces of information that clinicians need when appraising the…

信息检索 · 计算机科学 2020-05-25 Benjamin E. Nye , Ani Nenkova , Iain J. Marshall , Byron C. Wallace

With the development of biomedical science, researchers have increasing access to an abundance of studies focusing on similar research questions. There is a growing interest in the integration of summary information from those studies to…

统计方法学 · 统计学 2023-11-13 Jianxuan Zang , K. C. G. Chan , Fei Gao

Identifying patient subgroups with different treatment responses is an important task to inform medical recommendations, guidelines, and the design of future clinical trials. Existing approaches for treatment effect estimation primarily…

统计方法学 · 统计学 2025-12-10 Vincent Jeanselme , Chang Ho Yoon , Fabian Falck , Brian Tom , Jessica Barrett

I propose a finite sample inference procedure that uses a likelihood function derived from the randomization process within an experiment to conduct inference on various quantities that capture heterogeneous intervention effects. One such…

统计方法学 · 统计学 2020-09-03 Amanda Kowalski

Understanding the pathways whereby an intervention has an effect on an outcome is a common scientific goal. A rich body of literature provides various decompositions of the total intervention effect into pathway specific effects.…

统计方法学 · 统计学 2020-01-20 David Benkeser

For randomized trials that use text as an outcome, traditional approaches for assessing treatment impact require that each document first be manually coded for constructs of interest by trained human raters. This process, the current…

统计方法学 · 统计学 2024-08-05 Reagan Mozer , Luke Miratrix