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We utilize a model of Wilson-Cowan oscillators to investigate structure-function relationships in the human brain by means of simulations of the spontaneous dynamics of brain networks generated through human connectome data. This allows us…

神经元与认知 · 定量生物学 2023-06-14 Youssef Kora , Salma Salhi , Jörn Davidsen , Christoph Simon

The static synaptic connectivity of neuronal circuits stands in direct contrast to the dynamics of their function. As in changing community interactions, different neurons can participate actively in various combinations to effect behaviors…

神经元与认知 · 定量生物学 2024-02-29 Luciano Dyballa , Samuel Lang , Alexandra Haslund-Gourley , Eviatar Yemini , Steven W. Zucker

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

神经元与认知 · 定量生物学 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

We present a theory of pattern formation in growing domains inspired by biological examples of tissue development. Gradients of signaling molecules regulate growth, while growth changes these graded chemical patterns by dilution and…

When the human brain manifests the birth of organised communication among local and large-scale neuronal populations activity remains undescribed. We report, in resting-state EEG source-estimates of 100 infants at term age, the existence of…

神经元与认知 · 定量生物学 2020-09-08 Steve Mehrkanoon

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

应用统计 · 统计学 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

神经元与认知 · 定量生物学 2013-10-16 Marcus Kaiser

Despite the progress in deep learning networks, efficient learning at the edge (enabling adaptable, low-complexity machine learning solutions) remains a critical need for defense and commercial applications. We envision a pipeline to…

Criticality has been conjectured as an integral part of neuronal network dynamics. Operating at a critical threshold requires precise parameter tuning and a corresponding mechanism remains an open question. Recent studies have suggested…

神经元与认知 · 定量生物学 2021-04-19 Nikita Gutjahr , Philipp Hövel , Aline Viol

The underlying anatomical structure is fundamental to the study of brain networks, but the role of brainstem from a structural perspective is not very well understood. We conduct a computational and graph-theoretical study of the human…

神经元与认知 · 定量生物学 2023-04-26 Salma Salhi , Youssef Kora , Gisu Ham , Hadi Zadeh Haghighi , Christoph Simon

A paradigmatic framework to study the phenomenon of spontaneous collective synchronization is provided by the Kuramoto model comprising a large collection of limit-cycle oscillators of distributed frequencies that are globally coupled…

适应与自组织系统 · 物理学 2020-09-08 Mrinal Sarkar , Shamik Gupta

The detailed functioning of the human brain is still poorly understood. Brain simulations are a well-established way to complement experimental research, but must contend with the computational demands of the approximately $10^{11}$ neurons…

分布式、并行与集群计算 · 计算机科学 2025-10-01 Fabian Czappa , Marvin Kaster , Felix Wolf

This paper addresses the question of the brain's critical dynamics after an injury such as a stroke. It is hypothesized that the healthy brain operates near a phase transition (critical point), which provides optimal conditions for…

神经元与认知 · 定量生物学 2023-08-01 Jakub Janarek , Zbigniew Drogosz , Jacek Grela , Jeremi K. Ochab , Paweł Oświęcimka

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

We analyze functional magnetic resonance imaging (fMRI) data from the Human Connectome Project (HCP) to match brain activities during a range of cognitive tasks. Our findings demonstrate that even basic linear machine learning models can…

神经元与认知 · 定量生物学 2025-10-08 Valeriya Kirova , Dzerassa Kadieva , Daniil Vlasenko , Isak B. Blank , Fedor Ratnikov

Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve…

神经元与认知 · 定量生物学 2016-12-21 Ann Sizemore , Chad Giusti , Ari Kahn , Richard F. Betzel , Danielle S. Bassett

There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with…

机器学习 · 统计学 2021-09-14 Meimei Liu , Zhengwu Zhang , David B. Dunson

We analyze the influence of music in a network of FitzHugh-Nagumo oscillators with empirical structural connectivity measured in healthy human subjects. We report an increase of coherence between the global dynamics in our network and the…

适应与自组织系统 · 物理学 2022-06-10 Jakub Sawicki , Lenz Hartmann , Rolf Bader , Eckehard Schöll

Experimental fMRI studies have shown that spontaneous brain activity i.e. in the absence of any external input, exhibit complex spatial and temporal patterns of co-activity between segregated brain regions. These so-called large-scale…

适应与自组织系统 · 物理学 2015-06-23 Vesna Vuksanović , Philipp Hövel

We investigate the connection between the dynamics of synchronization and the modularity on complex networks. Simulating the Kuramoto's model in complex networks we determine patterns of meta-stability and calculate the modularity of the…

无序系统与神经网络 · 物理学 2009-11-11 Alex Arenas , Albert Diaz-Guilera