相关论文: A model for the oscillatory flow in the cerebral a…
A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…
MRI measurements from a decade-old study of the physical properties of brain tissue observed a dynamic, pulsating fluid flow in the interstitial spaces of the brain attributed to the cardiac cycle. The effects of this cyclic flow pattern on…
This work is motivated by the interest in determining the effect of the micro-anatomy of the spinal subarachnoid space on the cerebrospinal fluid flow and on the associated transport of solutes. To that aim, we focus on a canonical model…
Two-dimensional laminar flow of a viscous fluid induced by peristalsis due to a moving wall wave has been studied previously for a rectangular channel, a circular tube, and a concentric circular annulus. Here we study peristaltic flow in a…
We apply the lubrication approximation to solve for the flow generated by a peristaltic traveling wave in a finite, planar channel, and examine the effect of channel length. Cerebrospinal fluid (CSF) is hypothesized to be peristaltically…
Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…
We develop a theory of fluid--structure interaction (FSI) between an oscillatory Newtonian fluid flow and a compliant conduit. We consider the canonical geometries of a 2D channel with a deformable top wall and an axisymmetric deformable…
Previous studies on peristalsis, the pumping of fluid along a channel by wave-like displacements of the channel walls, have shown that the elastic properties of the channel and the peristaltic wave shape can influence the flow rate.…
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…
Fluid-structure interactions are ubiquitous in nature and technology. However, the systems are often so complex that numerical simulations or ad hoc assumptions must be used to gain insight into the details of the complex interactions…
Complex fluids flow in complex ways in complex structures. Transport of water and various organic and inorganic molecules in the central nervous system are important in a wide range of biological and medical processes [C. Nicholson, and S.…
Deformable microchannels emulate a key characteristic of soft biological systems and flexible engineering devices: the flow-induced deformation of the conduit due to slow viscous flow within. Elucidating the two-way coupling between…
Characterizing the dynamics of a cantilever in channel flow is relevant to applications ranging from snoring to energy harvesting. Aeroelastic flutter induces large oscillating amplitudes and sharp changes with frequency that impact the…
We investigate the linear Floquet stability of two fluid layers undergoing oscillations in the direction parallel to the flexible wall that separates them. This canonical configuration is inspired by the cerebrospinal fluid flow in the…
We study the flow of a generalized Newtonian fluid, characterized by a power-law model, through a channel consisting of a wall with a flexible membrane under longitudinal tension. It is assumed that at steady state the flow through the…
When two spherical particles submerged in a viscous fluid are subjected to an oscillatory flow, they align themselves perpendicular to the direction of the flow leaving a small gap between them. The formation of this compact structure is…
The cochlea is our fluid-filled organ of hearing with a unique spiral shape. The physiological role of this shape remains unclear. Previous research has paid only little attention to the occurrence of transverse flow in the cochlea, in…
The dynamic flow of cerebrospinal fluid (CSF) in brain ventricles exhibits flow features on several scales, both spatially and temporally. Most analysis of this complex flow and the accompanying transport has used instantaneous (Eulerian)…
Blood flow in arterial systems can be described by the three-dimensional Navier-Stokes equations within a time-dependent spatial domain that accounts for the elasticity of the arterial walls. In this article blood is treated as an…
Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests,…