相关论文: Three Dimensional Optimization of Scaffold Porosit…
Development of additive manufacturing in last decade greatly improves tissue engineering. During the manufacturing of porous scaffold, simplified but functionally equivalent models are getting focused for practically reasons. Scaffolds can…
Reinforced elastic sheets surround us in daily life, from concrete shell buildings to biological structures such as the arthropod exoskeleton or the venation network of dicotyledonous plant leaves. Natural structures are often highly…
Healing of Tendon-bone interface(TBI) injuries is slow and is often repaired with scar tissue formation that compromises normal function. Despite the increasing maturity of surgical techniques, re-tearing of the rotator cuff after surgery…
Recent developments in the field of computational modeling of fracture have opened up possibilities for designing structures against failure. A special case, called interfacial fracture or delamination, can occur in loaded composite…
Nowadays, additive manufacturing processes greatly simplify the production of openwork workpiece providing new opportunities for workpieces design. Based on Nature knowledge, a new bio-inspired workpiece structural optimization approach is…
This paper presents a density-based topology optimization approach to design structures under self-weight load. Such loads change their magnitude and/or location as the topology optimization advances and pose several unique challenges,…
A porous scaffold is a three-dimensional network structure composed of a large number of pores, and triply periodic minimal surfaces (TPMSs) are one of conventional tools for designing porous scaffolds. However, discontinuity,…
The regeneration of oral and craniofacial bone defects ranging from minor periodontal and peri-implant defects to large and critical lesions imposes a substantial global health burden. Conventional therapies are associated with several…
The paper describes the first exact results in optimal design of three-phase elastic structures. Two isotropic materials, the "strong" and the "weak" one, are laid out with void in a given two-dimensional domain so that the compliance plus…
The regeneration of the ruptured scapholunate interosseous ligament (SLIL) represents a clinical challenge. Here, we propose the use of a Bone-Ligament-Bone (BLB) 3D-printed polyethylene terephthalate (PET) scaffold for achieving mechanical…
This article combines shape optimization and homogenization techniques by looking for the optimal design of the microstructure in composite materials and of scaffolds. The development of materials with specific properties is of huge…
The inclusion of small amounts of copper is often reported to enhance the mechanical and biointegrative performance of bioceramics towards tissue engineering applications. In this work, 3D scaffolds were additively manufactured by…
The paper is devoted to the shape optimization of microstructures generating porous locally periodic materials saturated by viscous fluids. At the macroscopic level, the porous material is described by the Biot model defined in terms of the…
A common representation of a three dimensional object in computer applications, such as graphics and design, is in the form of a triangular mesh. In many instances, individual or groups of triangles in such representation need to satisfy…
Bone is a stiff and though, hierarchical and continuously evolving material that optimizes its structure to respond to mechanical stimuli, which also govern growth and remodeling processes. However, a full understanding of the underlying…
The paper presents a topology optimization approach that designs an optimal structure, called a self-supporting structure, which is ready to be fabricated via additive manufacturing without the usage of additional support structures. Such…
Topology optimization is an important basis for the design of components. Here, the optimal structure is found within a design space subject to boundary conditions. Thereby, the specific material law has a strong impact on the final design.…
A 3-D porous apatite scaffold (B-HA), recently obtained through biomorphic transformation of a natural wood, is investigated on its multi-scale porous structure determining superior mechanical properties and biological behaviour. B-HA shows…
A porous fence can be used as a shelter to reduce wind-induced erosion and the dispersion of dust particles from sand piles. Although many experimental and numerical studies have been carried out to analyze the effect of a porous fence on…
Topology optimization is able to maximally leverage the high DOFs and mechanical potentiality of porous foams but faces three fundamental challenges: conforming to free-form outer shapes, maintaining geometric connectivity between adjacent…