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相关论文: Lockdown interventions in SIR model: Is the reprod…

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As of November 2020, the number of COVID-19 cases is increasing rapidly in many countries. In Europe, the virus spread slowed considerably in the late spring due to strict lockdown, but a second wave of the pandemic grew throughout the…

定量方法 · 定量生物学 2020-11-25 Kristoffer Rypdal , Filippo Maria Bianchi , Martin Rypdal

This research quantifies the various South African lockdown regimes, for the SARS-CoV-2 pandemic, in terms of the basic reproduction number, $r_0$. It further calculates the levels of immunity required for these selfsame lockdown regimes to…

种群与进化 · 定量生物学 2020-09-02 Simon Childs

We study variants of the SEIR model for interpreting some qualitative features of the statistics of the Covid-19 epidemic in France. Standard SEIR models distinguish essentially two regimes: either the disease is controlled and the number…

种群与进化 · 定量生物学 2020-06-25 Jean Dolbeault , Gabriel Turinici

The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

During pandemic events, strategies such as social distancing can be fundamental to curb viral spreading. Such actions can reduce the number of simultaneous infections and mitigate the disease spreading, which is relevant to the risk of a…

物理与社会 · 物理学 2021-02-24 Marco A. Amaral , Marcelo M. de Oliveira , Marco A. Javarone

We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

The mathematical interpretation of interventions for the mitigation of epidemics and pandemics in the literature often involves finding the optimal time to initiate an intervention and/or the use of infections to manage impact. Whilst these…

种群与进化 · 定量生物学 2023-05-17 James Van Yperen , Eduard Campillo-Funollet , Rebecca Inkpen , Anjum Memon , Anotida Madzvamuse

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

种群与进化 · 定量生物学 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

种群与进化 · 定量生物学 2016-03-29 Chantal Nguyen , Jean M. Carlson

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

This paper studies algorithmic strategies to effectively reduce the number of infections in susceptible-infected-recovered (SIR) epidemic models. We consider a Markov chain SIR model and its two instantiations in the deterministic SIR…

最优化与控制 · 数学 2020-11-24 Yuhao Yi , Liren Shan , Philip E. Paré , Karl H. Johansson

During decades, mathematical models have been used to predict the behavior of physical and biologic systems, and to define strategies aiming the minimization of the effects regarding different types of diseases. In the present days, the…

No, they can't. Epidemic spread is characterized by exponentially growing dynamics, which are intrinsically unpredictable. The time at which the growth in the number of infected individuals halts and starts decreasing cannot be calculated…

种群与进化 · 定量生物学 2022-05-20 Mario Castro , Saúl Ares , José A. Cuesta , Susanna Manrubia

To combat the coronavirus disease 2019 (COVID-19) pandemic, the world has vaccination, plasma therapy, herd immunity, and epidemiological interventions as few possible options. The COVID-19 vaccine development is underway and it may take a…

机器学习 · 计算机科学 2020-08-26 Hanuman Verma , Akshansh Gupta , Utkarsh Niranjan

We study the effectiveness of tracking and testing in mitigating or suppressing epidemic outbreaks, in combination with or as an alternative to quarantines and global lockdowns. We study these intervention methods on a network-based SEIR…

种群与进化 · 定量生物学 2020-07-15 Yoav Kolumbus , Noam Nisan

Transmission rates in epidemic outbreaks may vary over time depending on the societal response. Non-pharmacological mitigation strategies such as social distancing and the adoption of protective equipment aim precisely at reducing…

种群与进化 · 定量生物学 2020-12-24 Elisa Franco

The importance of a strict quarantine has been widely debated during the COVID-19 epidemic even from the purely epidemiological point of view. One argument against strict lockdown measures is that once the strict quarantine is lifted, the…

物理与社会 · 物理学 2021-02-03 Varun Nimmagadda , Oleg Kogan , Evgeniy Khain

In this work we present a mathematical model that integrates the epidemiological dynamics of a vector-borne disease (SIR-SI) with Lotka Volterra predator prey ecological interactions. The study analyzes how the presence of natural predators…

最优化与控制 · 数学 2026-02-09 Rocio Balderrama , Ignacio Ceresa Dussel , Constanza Sanchez de la Vega

We consider an SIS-type epidemic process that evolves on a known graph. We assume that a fixed curing budget can be allocated at each instant to the nodes of the graph, towards the objective of minimizing the expected extinction time of the…

社会与信息网络 · 计算机科学 2015-10-22 Kimon Drakopoulos , Asuman Ozdaglar , John N. Tsitsiklis

COVID-19 is a global epidemic. Till now, there is no remedy for this epidemic. However, isolation and social distancing are seemed to be effective preventive measures to control this pandemic. Therefore, in this paper, an optimization…