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The density ratio model (DRM) provides a flexible and useful platform for combining information from multiple sources. In this paper, we consider statistical inference under two-sample DRMs with additional parameters defined through and/or…

统计理论 · 数学 2021-03-01 Meng Yuan , Pengfei Li , Changbao Wu

We present a new mathematical model to explicitly capture the effects that the three restriction measures: the lockdown date and duration, social distancing and masks, and, schools and border closing, have in controlling the spread of…

种群与进化 · 定量生物学 2020-08-25 Liam Dowling Jones , Malik Magdon-Ismail , Laura Mersini-Houghton , Steven Meshnick

We define a four-parameter extended Rayleigh distribution, and obtain several mathematical properties including a stochastic representation. We construct a regression from the new distribution. The estimation is done by maximum likelihood.…

Machine learning methods offer great promise for fast and accurate detection and prognostication of COVID-19 from standard-of-care chest radiographs (CXR) and computed tomography (CT) images. Many articles have been published in 2020…

We present three data driven model-types for COVID-19 with a minimal number of parameters to provide insights into the spread of the disease that may be used for developing policy responses. The first is exponential growth, widely studied…

种群与进化 · 定量生物学 2022-05-25 Andrea L. Bertozzi , Elisa Franco , George Mohler , Martin B. Short , Daniel Sledge

In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…

种群与进化 · 定量生物学 2021-01-01 Reza Sameni

The Covid-19 pandemic has made clear the need to improve modern multivariate time-series forecasting models. Current state of the art predictions of future daily deaths and, especially, hospital resource usage have confidence intervals that…

种群与进化 · 定量生物学 2020-06-25 Richard Bao , August Chen , Jethin Gowda , Shiva Mudide

We analytically study the SEIR (Susceptible Exposed Infectious Removed) epidemic model. The aim is to provide simple analytical expressions for the peak and asymptotic values and their characteristic times of the populations affected by the…

种群与进化 · 定量生物学 2020-12-29 Nicola Piovella

We introduce a new method for inference in stochastic epidemic models which uses recursive multinomial approximations to integrate over unobserved variables and thus circumvent likelihood intractability. The method is applicable to a class…

统计方法学 · 统计学 2021-02-24 Nick Whiteley , Lorenzo Rimella

Over the past two decades there has been a number of global outbreaks of viral diseases. This has accelerated the efforts to model and forecast the disease spreading, in order to find ways to confine the spreading regionally and between…

In this project, identifiability, observability and uncertainty properties of the deterministic and Chain Binomial stochastic SIR, SEIR and SEIAR epidemiological models are studied. Techniques for modeling overdispersion are investigated…

应用统计 · 统计学 2024-05-29 Jonas Hjulstad

Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

统计方法学 · 统计学 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

Practical parameter identifiability in ODE-based epidemiological models is a known issue, yet one that merits further study. It is essentially ubiquitous due to noise and errors in real data. In this study, to avoid uncertainty stemming…

统计方法学 · 统计学 2024-06-27 Q. Y. Chen , Z. Rapti , Y. Drossinos , J. Cuevas-Maraver , G. A. Kevrekidis , P. G. Kevrekidis

The recent COVID-19 pandemic has promoted vigorous scientific activity in an effort to understand, advice and control the pandemic. Data is now freely available at a staggering rate worldwide. Unfortunately, this unprecedented level of…

应用统计 · 统计学 2024-01-31 Yuansan Liu , Saransh Srivastava , Zuo Huang , Felisa J. Vázquez-Abad

We propose an SEIARD mathematical model to investigate the current outbreak of coronavirus disease (COVID-19) in Mexico. We conduct a detailed analysis of this model and demonstrate its application using publicly reported data. We calculate…

种群与进化 · 定量生物学 2021-02-23 Ugo Avila-Ponce de León , Ángel G. C. Pérez , Eric Avila-Vales

The rapid finding of effective therapeutics requires the efficient use of available resources in clinical trials. The use of covariate adjustment can yield statistical estimates with improved precision, resulting in a reduction in the…

统计方法学 · 统计学 2021-09-10 Nicholas Williams , Michael Rosenblum , Iván Díaz

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

种群与进化 · 定量生物学 2020-11-17 Christian Gourieroux , Yang Lu

We present a class of SEIR Markov chain models for infectious diseases observed over discrete time in a random human population living in a closed environment. The population changes over time through random births, deaths, and transitions…

种群与进化 · 定量生物学 2019-07-30 Divine Wanduku , Chinmoy Rahul

In this paper, a generalized fractional-order SEIR model is proposed, denoted by SEIQRP model, which has a basic guiding significance for the prediction of the possible outbreak of infectious diseases like COVID-19 and other insect diseases…

种群与进化 · 定量生物学 2020-04-30 Conghui Xu , Yongguang Yu , QuanChen Yang , Zhenzhen Lu

The main objective of this work is to test whether some stochastic models typically used in financial markets could be applied to the COVID-19 pandemic. To this end we have implemented the ARIMAX and Cox-Ingersoll-Ross (CIR) models…

种群与进化 · 定量生物学 2023-01-24 Julio Guerrero , Maria del Carmen Galiano , Giuseppe Orlando