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Global pandemics, such as the recent COVID-19 crisis, highlight the need for stochastic epidemic models that can capture the randomness inherent in the spread of disease. Such models must be accompanied by methods for estimating parameters…

定量方法 · 定量生物学 2026-04-13 Vincent Wieland , Nils Wassmuth , Lorenzo Contento , Martin Kühn , Jan Hasenauer

During the current COVID-19 pandemic, decision makers are tasked with implementing and evaluating strategies for both treatment and disease prevention. In order to make effective decisions, they need to simultaneously monitor various…

统计方法学 · 统计学 2023-09-13 Edward L. Boone , Abdel-Salam G. Abdel-Salam , Indranil Sahoo , Ryad Ghanam , Xi Chen , Aiman Hanif

Obtaining accurate forecasts for the evolution of epidemic outbreaks from deterministic compartmental models represents a major theoretical challenge. Recently, it has been shown that these models typically exhibit trajectories' degeneracy,…

Variational methods for parameter estimation are an active research area, potentially offering computationally tractable heuristics with theoretical performance bounds. We build on recent work that applies such methods to network data, and…

统计理论 · 数学 2013-10-30 Peter Bickel , David Choi , Xiangyu Chang , Hai Zhang

The asymptotic variance of the maximum likelihood estimate is proved to decrease when the maximization is restricted to a subspace that contains the true parameter value. Maximum likelihood estimation allows a systematic fitting of…

统计理论 · 数学 2018-01-31 Marie Turčičová , Jan Mandel , Kryštof Eben

We study the SIR epidemiological model, with a variable contagion rate, applied to the evolution of COVID19 in Cuba. It is highlighted that an increase in the predictive character depends on understanding the dynamics for the temporal…

种群与进化 · 定量生物学 2020-04-24 Nana Cabo Bizet , Alejandro Cabo Montes de Oca

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model with a contact rate that fluctuates seasonally. Through the use of a nonlinear, stochastic projection, we are able to analytically determine the…

种群与进化 · 定量生物学 2013-09-11 Eric Forgoston , Ira B. Schwartz

Calibration of a SIR (Susceptibles-Infected-Recovered) model with official international data for the COVID-19 pandemics provides a good example of the difficulties inherent the solution of inverse problems. Inverse modeling is set up in a…

种群与进化 · 定量生物学 2020-06-09 Mauro Giudici , Alessandro Comunian , Romina Gaburro

We present a compartmental SEIAR model of epidemic spread as a generalization of the SEIR model. We believe that the asymptomatic infectious cohort is an omitted part of the understanding of the epidemic dynamics of disease COVID-19. We…

种群与进化 · 定量生物学 2020-04-07 Lenka Pribylova , Veronika Hajnova

With COVID-19 now pervasive, identification of high-risk individuals is crucial. Using data from a major healthcare provider in Southwestern Pennsylvania, we develop survival models predicting severe COVID-19 progression. In this endeavor,…

A nonlinear partial differential equation (PDE) based compartmental model of COVID-19 provides a continuous trace of infection over space and time. Finer resolutions in the spatial discretization, the inclusion of additional model…

计算工程、金融与科学 · 计算机科学 2022-08-04 Sudhi P. V. , Victorita Dolean , Pierre Jolivet , Brandon Robinson , Jodi D. Edwards , Tetyana Kendzerska , Abhijit Sarkar

COVID-19 has resulted in a public health global crisis. The pandemic control necessitates epidemic models that capture the trends and impacts on infectious individuals. Many exciting models can implement this but they lack practical…

计算机与社会 · 计算机科学 2021-04-13 Ou Deng , Kiichi Tago , Qun Jin

Fitting Susceptible-Infected-Recovered (SIR) models to incidence data is problematic when not all infected individuals are reported. Assuming an underlying SIR model with general but known distribution for the time to recovery, this paper…

种群与进化 · 定量生物学 2021-08-16 Imelda Trejo , Nicolas Hengartner

Natural fluctuations have played a crucial role in affecting the dynamics of pervasive diseases such as the coronavirus. Examining the effects of irregular unsettling disturbances on epidemic models is important for understanding these…

动力系统 · 数学 2024-12-17 Daniel Tesfay , Almaz Tesfay , James Brannan

We propose two stochastic models for the Coronavirus pandemic. The statistical properties of the models, in particular the correlation functions and the probability density function, have duly been computed. Our models, which generalises a…

医学物理 · 物理学 2020-12-04 Giorgio Sonnino , Fernando Mora , Pasquale Nardone

We propose an SEIR-type meta-population model to simulate and monitor the Covid-19 epidemic evolution. The basic model consists of seven compartments, namely susceptible (S), exposed (E), three infective classes, recovered (R), and deceased…

种群与进化 · 定量生物学 2020-11-18 Vinicius V. L. Albani , Roberto M. Velho , Jorge P. Zubelli

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

统计方法学 · 统计学 2025-08-04 Lorenzo Rimella , Christopher Jewell , Paul Fearnhead

This paper proposes a feedback design that effectively copes with uncertainties for reliable epidemic monitoring and control. There are several optimization-based methods to estimate the parameters of an epidemic model by utilizing past…

最优化与控制 · 数学 2023-04-06 Muhammad Umar B. Niazi , Philip E. Paré , Karl H. Johansson

The Susceptible-Exposed-Infectious-Recovered (SEIR) model is applied in several countries to ascertain the spread of the coronavirus disease 2019 (COVID-19). We consider discrete-time SEIR epidemic model in a closed system which does not…

动力系统 · 数学 2021-05-04 U. A. Rozikov , S. K. Shoyimardonov

In this paper, based on the Akaike information criterion, root mean square error and robustness coefficient, a rational evaluation of various epidemic models/methods, including seven empirical functions, four statistical inference methods…

种群与进化 · 定量生物学 2021-09-16 Wuyue Yang , Dongyan Zhang , Liangrong Peng , Changjing Zhuge , Liu Hong
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