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With increasing and extensive use of electronic health records, clinicians are often under time pressure when they need to retrieve important information efficiently among large amounts of patients' health records in clinics. While a search…

信息检索 · 计算机科学 2020-08-05 Zhiyun Ren , Bo Peng , Titus K. Schleyer , Xia Ning

Combining patient-level data from clinical trials can connect rare phenomena with clinical endpoints, but statistical techniques applied to a single trial may become problematical when trials are pooled. Estimating the hazard of a binary…

Mental health diseases affect children's lives and well-beings which have received increased attention since the COVID-19 pandemic. Analyzing psychiatric clinical notes with topic models is critical to evaluating children's mental status…

计算与语言 · 计算机科学 2024-11-04 Hanwen Ye , Tatiana Moreno , Adrianne Alpern , Louis Ehwerhemuepha , Annie Qu

The clinical notes are usually typed into the system by physicians. They are typically required to be marked by standard medical codes, and each code represents a diagnosis or medical treatment procedure. Annotating these notes is time…

机器学习 · 计算机科学 2023-05-10 Guodong Liu

Post-Traumatic Stress Disorder (PTSD) is a multifaceted mental health condition, particularly challenging for individuals with pre-existing medical conditions. This review critically examines the intersection of PTSD and chronic illnesses…

计算与语言 · 计算机科学 2026-01-15 Zaber Al Hassan Ayon , Nur Hafieza Ismail , Nur Shazwani Kamarudin

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

定量方法 · 定量生物学 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

As social changes accelerate, the incidence of psychosomatic disorders has significantly increased, becoming a major challenge in global health issues. This necessitates an innovative knowledge system and analytical methods to aid in…

人工智能 · 计算机科学 2024-12-25 Zihan Zhou , Ziyi Zeng , Wenhao Jiang , Yihui Zhu , Jiaxin Mao , Yonggui Yuan , Min Xia , Shubin Zhao , Mengyu Yao , Yunqian Chen

Some patients with COVID-19 show changes in signs and symptoms such as temperature and oxygen saturation days before being positively tested for SARS-CoV-2, while others remain asymptomatic. It is important to identify these subgroups and…

统计方法学 · 统计学 2024-10-22 Xiaoran Ma , Wensheng Guo , Mengyang Gu , Len Usvyat , Peter Kotanko , Yuedong Wang

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive…

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

人工智能 · 计算机科学 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Chronic kidney disease (CKD) has a poor prognosis due to excessive risk factors and comorbidities associated with it. The early detection of CKD faces challenges of insufficient medical histories of positive patients and complicated risk…

机器学习 · 计算机科学 2020-12-08 Yu Wang , Ziqiao Guan , Wei Hou , Fusheng Wang

Background: A large number of neurology case reports have been published, but it is a challenging task for human medical experts to explore all of these publications. Text mining offers a computational approach to investigate neurology…

定量方法 · 定量生物学 2019-06-10 Amir Karami , Mehdi Ghasemi , Souvik Sen , Marcos Moraes , Vishal Shah

Electronic health records are a valuable data source for investigating health-related questions, and propensity score analysis has become an increasingly popular approach to address confounding bias in such investigations. However, because…

A biological understanding is key for managing medical conditions, yet psychological and social aspects matter too. The main problem is that these two aspects are hard to quantify and inherently difficult to communicate. To quantify…

人机交互 · 计算机科学 2020-10-14 Wonyoung So , Edyta P. Bogucka , Sanja Šćepanović , Sagar Joglekar , Ke Zhou , Daniele Quercia

Compartmental models based on tracer mass balance are extensively used in clinical and pre-clinical nuclear medicine in order to obtain quantitative information on tracer metabolism in the biological tissue. This paper is the first of a…

定量方法 · 定量生物学 2018-08-21 Fabrice Delbary , Sara Garbarino , Valentina Vivaldi

We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent…

机器学习 · 计算机科学 2019-02-12 Duc Thanh Anh Luong , Varun Chandola

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

其他定量生物学 · 定量生物学 2025-10-20 Syed Ibad Hasnain

Patient subtyping based on temporal observations can lead to significantly nuanced subtyping that acknowledges the dynamic characteristics of diseases. Existing methods for subtyping trajectories treat the evolution of clinical observations…

机器学习 · 计算机科学 2018-11-30 Nikhil Galagali , Minnan Xu-Wilson

Comparing outcomes across treatments is essential in medicine and public policy. To do so, researchers typically estimate a set of parameters, possibly counterfactual, with each targeting a different treatment. Treatment-specific means are…

统计方法学 · 统计学 2025-10-07 Alec McClean , Yiting Li , Sunjae Bae , Mara A. McAdams-DeMarco , Iván Díaz , Wenbo Wu

A significant percentage of COVID-19 survivors experience ongoing multisystemic symptoms that often affect daily living, a condition known as Long Covid or post-acute-sequelae of SARS-CoV-2 infection. However, identifying scientific…

机器学习 · 计算机科学 2022-10-31 Robert Leaman , Rezarta Islamaj , Alexis Allot , Qingyu Chen , W. John Wilbur , Zhiyong Lu