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Composite likelihood inference has gained much popularity thanks to its computational manageability and its theoretical properties. Unfortunately, performing composite likelihood ratio tests is inconvenient because of their awkward…

统计计算 · 统计学 2014-08-01 Manuela Cattelan , Nicola Sartori

In modern scientific experiments, we frequently encounter data that have large dimensions, and in some experiments, such high dimensional data arrive sequentially rather than full data being available all at a time. We develop multiple…

统计方法学 · 统计学 2023-06-09 Rahul Roy , Shyamal K. De , Subir Kumar Bhandari

The mainstream of research in genetics, epigenetics and imaging data analysis focuses on statistical association or exploring statistical dependence between variables. Despite their significant progresses in genetic research, understanding…

基因组学 · 定量生物学 2018-05-14 Rong Jiao , Nan Lin , Zixin Hu , David A Bennett , Li Jin , Momiao Xiong

In this paper, we consider procedures for testing hypotheses on the dimension of the linear span generated by a growing number of $p\times p$ covariance matrices from independent $q$ populations. Under a proper limiting scheme where all the…

统计理论 · 数学 2026-02-16 Tianxing Mei , Chen Wang , Jianfeng Yao

The multiple testing procedure plays an important role in detecting the presence of spatial signals for large-scale imaging data. Typically, the spatial signals are sparse but clustered. This paper provides empirical evidence that for a…

统计理论 · 数学 2011-03-11 Chunming Zhang , Jianqing Fan , Tao Yu

Given a random sample of size $n$ from a $p$ dimensional random vector, where both $n$ and $p$ are large, we are interested in testing whether the $p$ components of the random vector are mutually independent. This is the so-called complete…

统计理论 · 数学 2022-01-24 Yongcheng Qi , Yingchao Zhou

We consider the estimation of large covariance and precision matrices from high-dimensional sub-Gaussian or heavier-tailed observations with slowly decaying temporal dependence. The temporal dependence is allowed to be long-range so with…

统计理论 · 数学 2019-12-23 Hai Shu , Bin Nan

Mass spectrometry (MS) is used widely in biomolecular structural analysis and is particularly dominant in the study of proteins. Despite its considerable power, state-of-the-art protein MS frequently suffers from limited reliability of…

This paper discusses an approach, based on the subsampling boostrap and FDR control, to improve the stability of feature selection. It furthermore presents the finite sample distribution of the correlation coefficient recently proposed by…

统计方法学 · 统计学 2020-06-29 Jonathan von Schroeder

Widely used methods for analyzing missing data can be biased in small samples. To understand these biases, we evaluate in detail the situation where a small univariate normal sample, with values missing at random, is analyzed using either…

统计理论 · 数学 2017-03-27 Paul T. von Hippel

Influence diagnosis is an integrated component of data analysis, but is severely under-investigated in a high-dimensional setting. One of the key challenges, even in a fixed-dimensional setting, is how to deal with multiple influential…

统计方法学 · 统计学 2017-02-07 Junlong Zhao , Chao Liu , Lu Niu , Chenlei Leng

Inverse probability of treatment weighting (IPTW) is a popular propensity score (PS)-based approach to estimate causal effects in observational studies at risk of confounding bias. A major issue when estimating the PS is the presence of…

In many real-world applications, it is common that a proportion of the data may be missing or only partially observed. We develop a novel two-sample testing method based on the Maximum Mean Discrepancy (MMD) which accounts for missing data…

统计方法学 · 统计学 2024-05-27 Yijin Zeng , Niall M. Adams , Dean A. Bodenham

Meta-analysis of multiple genome-wide association studies (GWAS) is effective for detecting single or multi marker associations with complex traits. We develop a flexible procedure ("STAMP") based on mixture models to perform region based…

统计方法学 · 统计学 2018-01-01 Andriy Derkach , Ruth M. Pfeiffer

In this article, we consider the problem of testing the independence between two random variables. Our primary objective is to develop tests that are highly effective at detecting associations arising from explicit or implicit functional…

统计方法学 · 统计学 2025-02-21 Seetharaman P , Sagnik Das , Angshuman Roy

Considerable interest has recently been focused on studying multiple phenotypes simultaneously in both epidemiological and genomic studies, either to capture the multidimensionality of complex disorders or to understand shared etiology of…

统计方法学 · 统计学 2015-11-26 Denis Agniel , Katherine P. Liao , Tianxi Cai

In particle physics, as in many areas of science, parameter inference relies on simulations to bridge the gap between theory and experiment. Recent developments in simulation-based inference have boosted the sensitivity of analyses;…

高能物理 - 唯象学 · 物理学 2026-04-23 Ezequiel Alvarez , Sean Benevedes , Manuel Szewc , Jesse Thaler

Weighting methods in causal inference have been widely used to achieve a desirable level of covariate balancing. However, the existing weighting methods have desirable theoretical properties only when a certain model, either the propensity…

机器学习 · 统计学 2023-05-24 Insung Kong , Yuha Park , Joonhyuk Jung , Kwonsang Lee , Yongdai Kim

This paper discusses the possible ways to analyse the data, adopting a matrix notation, so often used in Bioassays. The paper also reviews the Multistage Models (MM). The MM class of models is applied for extrapolation, to the region of…

应用统计 · 统计学 2013-06-25 Christos P. Kitsos , Nikolaos K. Tavoularis , Thomas L. Toulias , George Lolas

Simultaneously performing variable selection and inference in high-dimensional regression models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of…

统计方法学 · 统计学 2025-05-08 Marco Molinari , Magne Thoresen