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Science and technology have a growing need for effective mechanisms that ensure reliable, controlled performance from black-box machine learning algorithms. These performance guarantees should ideally hold conditionally on the input-that is…

机器学习 · 计算机科学 2025-03-28 Vincent Blot , Anastasios N Angelopoulos , Michael I Jordan , Nicolas J-B Brunel

Interpretable machine learning has emerged as central in leveraging artificial intelligence within high-stakes domains such as healthcare, where understanding the rationale behind model predictions is as critical as achieving high…

机器学习 · 计算机科学 2024-04-30 Christel Sirocchi , Martin Urschler , Bastian Pfeifer

We present a new estimator of the restricted mean survival time in randomized trials where there is right censoring that may depend on treatment and baseline variables. The proposed estimator leverages prognostic baseline variables to…

统计理论 · 数学 2016-08-22 Iván Díaz , Elizabeth Colantuoni , Daniel F. Hanley , Michael Rosenblum

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

Causal inference in multivariate time series is challenging due to the fact that the sampling rate may not be as fast as the timescale of the causal interactions. In this context, we can view our observed series as a subsampled version of…

统计方法学 · 统计学 2017-04-11 Alex Tank , Emily B. Fox , Ali Shojaie

Random forests are powerful non-parametric regression method but are severely limited in their usage in the presence of randomly censored observations, and naively applied can exhibit poor predictive performance due to the incurred biases.…

机器学习 · 统计学 2019-02-12 Alexander Hanbo Li , Jelena Bradic

In many important applications of precision medicine, the outcome of interest is time to an event (e.g., death, relapse of disease) and the primary goal is to identify the optimal individualized decision rule (IDR) to prolong survival time.…

统计方法学 · 统计学 2022-04-11 Yu Zhou , Lan Wang , Rui Song , Tuoyi Zhao

We consider the problem of estimating the distribution of time-to-event data that are subject to censoring and for which the event of interest might never occur, i.e., some subjects are cured. To model this kind of data in the presence of…

统计理论 · 数学 2018-06-05 François Portier , Ingrid Van Keilegom , Anouar El Ghouch

Perceived risk in automated driving is often measured as discrete scores that summarise riding experience but this obscures volatile peaks from sustained elevation. Here we treat discrete clipwise ratings as constraints on an unobserved…

人机交互 · 计算机科学 2026-03-17 Xiaolin He , Zirui Li , Xinwei Wang , Riender Happee , Meng Wang

Survival analysis concerns the task of predicting the time until an event occurs. Often used in the medical field, survival analysis deals with incomplete (i.e., censored) data, for instance, from patients who did not experience the event…

机器学习 · 计算机科学 2026-05-29 Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

统计方法学 · 统计学 2019-09-27 Chenyang Zhong , Robert Tibshirani

Increasingly, medical research is dependent on data collected for non-research purposes, such as electronic health records data (EHR). EHR data and other large databases can be prone to measurement error in key exposures, and unadjusted…

统计方法学 · 统计学 2020-05-13 Kyunghee Han , Thomas Lumley , Bryan E. Shepherd , Pamela A. Shaw

Time-to-event analysis, also known as survival analysis, aims to predict the time of occurrence of an event, given a set of features. One of the major challenges in this area is dealing with censored data, which can make learning algorithms…

机器学习 · 计算机科学 2023-07-25 Hyunjun Lee , Junhyun Lee , Taehwa Choi , Jaewoo Kang , Sangbum Choi

In clinical studies, the illness-death model is often used to describe disease progression. A subject starts disease-free, may develop the disease and then die, or die directly. In clinical practice, disease can only be diagnosed at…

统计方法学 · 统计学 2026-02-02 Marta Spreafico , Anja J. Rueten-Budde , Hein Putter , Marta Fiocco

In the era of MOOCs, online exams are taken by millions of candidates, where scoring short answers is an integral part. It becomes intractable to evaluate them by human graders. Thus, a generic automated system capable of grading these…

The COVID-19 pandemic has strained global public health, necessitating accurate diagnosis and intervention to control disease spread and reduce mortality rates. This paper introduces an interpretable deep survival prediction model designed…

计算机视觉与模式识别 · 计算机科学 2024-05-07 Zhusi Zhong , Jie Li , Zhuoqi Ma , Scott Collins , Harrison Bai , Paul Zhang , Terrance Healey , Xinbo Gao , Michael K. Atalay , Zhicheng Jiao

Wildfires pose a significantly increasing hazard to global ecosystems due to the climate crisis. Due to its complex nature, there is an urgent need for innovative approaches to wildfire prediction, such as machine learning. This research…

机器学习 · 计算机科学 2024-11-18 İrem Üstek , Miguel Arana-Catania , Alexander Farr , Ivan Petrunin

Survival models are a popular tool for the analysis of time to event data with applications in medicine, engineering, economics, and many more. Advances like the Cox proportional hazard model have enabled researchers to better describe…

机器学习 · 统计学 2021-02-16 Stefan Groha , Sebastian M Schmon , Alexander Gusev

Tree-based methods are popular nonparametric tools in studying time-to-event outcomes. In this article, we introduce a novel framework for survival trees and ensembles, where the trees partition the dynamic survivor population and can…

统计方法学 · 统计学 2020-01-14 Yifei Sun , Sy Han Chiou , Mei-Cheng Wang

The restricted mean survival time (RMST) has become a popular measure to summarize event times in longitudinal studies. Defined as the area under the survival function up to a time horizon $\tau$ > 0, the RMST can be interpreted as the life…

统计方法学 · 统计学 2024-11-05 Alina Schenk , Vanessa Basten , Matthias Schmid