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相关论文: The Origins of COVID-19

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Widespread growth signatures in COVID-19 confirmed case counts are reported, with sharp transitions between three distinct dynamical regimes (exponential, superlinear and sublinear). Through analytical and numerical analysis, a novel…

种群与进化 · 定量生物学 2021-03-26 Magdalena Djordjevic , Marko Djordjevic , Bojana Ilic , Stefan Stojku , Igor Salom

We are presenting COVID-19Base, a knowledgebase highlighting the biomedical entities related to COVID-19 disease based on literature mining. To develop COVID-19Base, we mine the information from publicly available scientific literature and…

The SARS-CoV-2 virus and COVID-19 disease have posed unprecedented and overwhelming demand, challenges and opportunities to domain, model and data driven modeling. This paper provides a comprehensive review of the challenges, tasks,…

计算机与社会 · 计算机科学 2021-08-05 Longbing Cao , Qing Liu

A new coronavirus disease, called COVID-19, appeared in the Chinese region of Wuhan at the end of last year; since then the virus spread to other countries, including most of Europe. We propose a differential equation governing the…

种群与进化 · 定量生物学 2020-09-15 Giorgio Sonnino , Pasquale Nardone

Proteins have evolved through mutations, amino acid substitutions, since life appeared on Earth, some 109 years ago. The study of these phenomena has been of particular significance because of their impact on protein stability, function,…

生物大分子 · 定量生物学 2023-10-25 Jorge A. Vila

COVID-19 is one of the most important topic these days, specifically on search engines and news. While fake news are easily shared, scientific papers are reliable sources where information can be extracted. With about 24,000 scientific…

数字图书馆 · 计算机科学 2020-05-04 Bernard Dousset , Josiane Mothe

We propose a mathematical model to analyze the time evolution of the total number of infected population with Covid-19 disease at a region in the ongoing pandemic. Using the available data of Covid-19 infected population on various…

种群与进化 · 定量生物学 2020-08-17 Nilmani Mathur , Gargi Shaw

Since late 2019, COVID-19 has quickly emerged as the newest biomedical domain, resulting in a surge of new information. As with other emergent domains, the discussion surrounding the topic has been rapidly changing, leading to the spread of…

计算与语言 · 计算机科学 2021-10-15 Sharon Levy , Kevin Mo , Wenhan Xiong , William Yang Wang

Since the outbreak of the COVID-19, there have been many scientific publications studying the COVID-19. The purpose of this study is to identify the research trend, collaboration pattern, most influential elements, etc. from scientific…

数字图书馆 · 计算机科学 2024-07-24 Xuezhou Fan

In the course of evolution, proteins undergo important changes in their amino acid sequences, while their three-dimensional folded structure and their biological function remain remarkably conserved. Thanks to modern sequencing techniques,…

生物大分子 · 定量生物学 2019-10-07 Simona Cocco , Christoph Feinauer , Matteo Figliuzzi , Remi Monasson , Martin Weigt

This work takes a first look at domain names related to COVID-19 (Cov19doms in short), using a large-scale registered Internet domain name database, which accounts for 260M of distinct domain names registered for 1.6K of distinct top-level…

计算机与社会 · 计算机科学 2021-02-11 Ryo Kawaoka , Daiki Chiba , Takuya Watanabe , Mitsuaki Akiyama , Tatsuya Mori

Countries are recording health information on the global spread of COVID-19 using different methods, sometimes changing the rules after a few days. They are all publishing the number of new individuals infected, cured and dead, along with…

种群与进化 · 定量生物学 2020-12-15 J. M. Calabuig , L. M. García-Raffi , A. García-Valiente , E. A. Sánchez-Pérez

In this review, we successively present the methods for phenomenological modeling of the evolution of reported and unreported cases of COVID-19, both in the exponential phase of growth and then in a complete epidemic wave. After the case of…

偏微分方程分析 · 数学 2023-10-02 J. Demongeot , P. Magal

Proteins, by virtue of their central role in most biological processes, represent one of the key subjects of the study of molecular evolution. Inherent to the indispensability of proteins for living cells is the fact that a given protein…

生物大分子 · 定量生物学 2007-05-23 Eric J. Deeds , Eugene I. Shakhnovich

The interconnected processes of protein folding, mutations, epistasis, and evolution have all been the subject of extensive analysis throughout the years due to their significance for structural and evolutionary biology. The origin…

种群与进化 · 定量生物学 2024-04-08 Jorge A. Vila

Norden E. Huang, Fangli Qiao and Ka Kit Tung presented a data-driven model for the COVID-19 epidemic in which the relevant functions depend on a set of seven parameters obtained from a statistical analysis of the available data. These…

物理与社会 · 物理学 2020-08-17 Charles Horvath

It has been conjectured that evolution exerted pressure to preserve amino acids bearing thermodynamic, kinetic, and functional roles. In this letter we show that the physical requirement to maintain protein stability gives rise to a…

统计力学 · 物理学 2007-05-23 Nikolay V. Dokholyan , Leonid A. Mirny , Eugene I. Shakhnovich

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

定量方法 · 定量生物学 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Since the coronavirus disease (COVID-19) outbreak in December 2019, studies have been addressing diverse aspects in relation to COVID-19 and Variant of Concern 202012/01 (VOC 202012/01) such as potential symptoms and predictive tools.…

机器学习 · 计算机科学 2021-02-02 Wasiq Khan , Abir Hussain , Sohail Ahmed Khan , Mohammed Al-Jumailey , Raheel Nawaz , Panos Liatsis

COVID-19 has caused thousands of deaths around the world and also resulted in a large international economic disruption. Identifying the pathways associated with this illness can help medical researchers to better understand the properties…

计算与语言 · 计算机科学 2022-05-03 Negin Karisani , Daniel E. Platt , Saugata Basu , Laxmi Parida
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