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The purpose of this paper is to model mathematically mechanical aspects of cardiac tissues. The latter constitute an elastic domain whose total volume remains constant. The time deformation of the heart tissue is modeled with the…

偏微分方程分析 · 数学 2023-02-24 Sebastien Court

Background-The electric field applied to the heart during defibrillation causes mechanical forces (electrostriction), and as a result the heart deforms. This paper analyses the physical origin of the deformation, and how significant it is.…

医学物理 · 物理学 2011-02-22 Michelle M. Fritz , Phil W. Prior , Bradley J. Roth

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. For this reason, many approaches have been developed to best estimate the cardiac muscle deformation, and to obtain a practical model to use in…

计算工程、金融与科学 · 计算机科学 2014-12-09 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

Deformation modeling of cardiac muscle is an important issue in the field of cardiac analysis. Many approaches have been developed to better estimate the cardiac muscle deformation, and to obtain a practical model to be used in diagnostic…

计算工程、金融与科学 · 计算机科学 2015-12-01 Ahmadreza Baghaie , Hamid Abrishami Moghaddam

This work proposes a stabilized space--time method for the monodomain equation coupled with the Rogers--McCulloch ionic model, which is widely used to simulate electrophysiological wave propagation in the cardiac tissue. By extending the…

数值分析 · 数学 2025-03-18 P. F. Antonietti , L. Dedè , G. Loli , M. Montardini , G. Sangalli , P. Tesini

Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that affect the dynamics of these spiral waves. By using an…

生物物理 · 物理学 2021-08-17 Mahesh Kumar Mulimani , Soling Zimik , Rahul Pandit

As a consequence of elasticity, mechanical deformations of crystals occur on a length scale comparable to their thickness. This is exemplified by applying a homogeneous electric field to a multi-domain ferroelectric crystal: as one domain…

材料科学 · 物理学 2009-11-11 Tobias Jungk , Akos Hoffmann , Elisabeth Soergel

This study uses a one dimensional fluid dynamics arterial network model to infer changes in hemodynamic quantities associated with pulmonary hypertension in mice. Data for this study include blood flow and pressure measurements from the…

On the basis of a quite realistic ionic Fenton--Karma model of the cardiac tissue we consider the problem of defibrillation by a local weak forcing. In contrast to other systems, this model accurately reproduces the most essential…

混沌动力学 · 物理学 2007-05-23 Ekaterina Zhuchkova , Boris Radnaev , Alexander Loskutov

Understanding the biomechanics of the heart in health and disease plays an important role in the diagnosis and treatment of heart failure. The use of computational biomechanical models for therapy assessment is paving the way for…

We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…

The molecular arrangement of lipids and proteins within biomembranes and monolayers gives rise to complex film morphologies as well as regions of distinct electrical surface potential, topographical and electrostatic nanoscale domains. To…

软凝聚态物质 · 物理学 2016-11-28 Elizabeth Drolle , W. F. D. Bennett , K. Hammond , Edward Lyman , Mikko Karttunen , Zoya Leonenko

This work deals with the numerical solution of the monodomain and bidomain models of electrical activity of myocardial tissue. The bidomain model is a system consisting of a possibly degenerate parabolic PDE coupled with an elliptic PDE for…

数值分析 · 数学 2008-07-03 Mostafa Bendahmane , Raimund Bürger , Ricardo Ruiz Baier

Ventricular tachycardia (VT) and ventricular fibrillation (VF) are lethal rhythm disorders, which are associated with the occurrence of abnormal electrical scroll waves in the heart. Given the technical limitations of imaging and probing,…

医学物理 · 物理学 2020-11-11 K. V. Rajany , Rupamanjari Majumder , Alok Ranjan Nayak , Rahul Pandit

Myocardial infarction significantly degrades heart function, and current treatments can bring forth serious cost and complications including blood clots and infections. To improve the current state of treatment, researchers are developing…

A rectangular plate of dielectric elastomer exhibiting gradients of material properties through its thickness will deform inhomogeneously when a potential difference is applied to compliant electrodes on its major surfaces, because each…

软凝聚态物质 · 物理学 2020-12-08 Yipin Su , Ray W. Ogden , Michel Destrade

We propose four novel mathematical models, describing the microscopic mechanisms of force generation in the cardiac muscle tissue, which are suitable for multiscale numerical simulations of cardiac electromechanics. Such models are based on…

亚细胞过程 · 定量生物学 2021-01-27 Francesco Regazzoni , Luca Dedè , Alfio Quarteroni

Pulmonary hypertension is a cardiovascular disorder manifested by elevated arterial blood pressure together with vessel wall stiffening and thickening due to alterations in collagen, elastin and smooth muscle cells. Hypoxia-induced (type 3)…

组织与器官 · 定量生物学 2022-02-28 Mansoor A. Haider , Katherine J. Pearce , Naomi C. Chesler , Nicholas A. Hill , Mette S. Olufsen

Cardiovascular diseases are best diagnosed using multiple modalities that assess both the heart's electrical and mechanical functions. While effective, imaging techniques like echocardiography and nuclear imaging are costly and not widely…

医学物理 · 物理学 2024-10-28 Sajjad Karimi , Shirin Karimi , Amit J. Shah , Gari D. Clifford , Reza Sameni

Background and Purpose: This study was designed to compare the effects of high-intensity interval training (HIT) and moderate-intensity continuous training (MOD) on functional recovery and cerebral plasticity during the first 2 weeks…

神经元与认知 · 定量生物学 2018-02-09 Caroline Pin-Barre , Annabelle Constans , Jeanick Brisswalter , Christophe Pellegrino , Jérôme Laurin