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Several efforts have been done to bring ROC analysis beyond (binary) classification, especially in regression. However, the mapping and possibilities of these proposals do not correspond to what we expect from the analysis of operating…

统计理论 · 数学 2013-10-17 Jose Hernandez-Orallo

Traditional machine learning follows a close-set assumption that the training and test set share the same label space. While in many practical scenarios, it is inevitable that some test samples belong to unknown classes (open-set). To fix…

机器学习 · 计算机科学 2023-02-23 Zitai Wang , Qianqian Xu , Zhiyong Yang , Yuan He , Xiaochun Cao , Qingming Huang

AUC (Area under the ROC curve) is an important performance measure for applications where the data is highly imbalanced. Learning to maximize AUC performance is thus an important research problem. Using a max-margin based surrogate loss…

人工智能 · 计算机科学 2016-12-28 Vishal Kakkar , Shirish K. Shevade , S Sundararajan , Dinesh Garg

The predictive quality of machine learning models is typically measured in terms of their (approximate) expected prediction error or the so-called Area Under the Curve (AUC) for a particular data distribution. However, when the models are…

机器学习 · 计算机科学 2018-02-08 Hiva Ghanbari , Katya Scheinberg

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

机器学习 · 计算机科学 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Risk prediction that capitalizes on emerging genetic findings holds great promise for improving public health and clinical care. However, recent risk prediction research has shown that predictive tests formed on existing common genetic…

机器学习 · 计算机科学 2025-08-20 Changshuai Wei , Qing Lu

Anomaly detection (AD) is a fundamental task for time-series analytics with important implications for the downstream performance of many applications. In contrast to other domains where AD mainly focuses on point-based anomalies (i.e.,…

In diagnostic studies, researchers frequently encounter imperfect reference standards with some misclassified labels. Treating these as gold standards can bias receiver operating characteristic (ROC) curve analysis. To address this issue,…

统计方法学 · 统计学 2025-02-13 Yifan Sun , Peijun Sang , Qinglong Tian , Pengfei Li

We propose new simultaneous inference methods for diagnostic trials with elaborate factorial designs. Instead of the commonly used total area under the receiver operating characteristic (ROC) curve, our parameters of interest are partial…

统计理论 · 数学 2023-02-22 Maximilian Wechsung , Frank Konietschke

While deep learning models often achieve high predictive accuracy, their predictions typically do not come with any provable guarantees on risk or reliability, which are critical for deployment in high-stakes applications. The framework of…

机器学习 · 计算机科学 2025-10-13 Christopher Yeh , Nicolas Christianson , Adam Wierman , Yisong Yue

When evaluating the performance of clinical machine learning models, one must consider the deployment population. When the population of patients with observed labels is only a subset of the deployment population (label selection), standard…

机器学习 · 计算机科学 2022-09-20 Conor K. Corbin , Michael Baiocchi , Jonathan H. Chen

The generalization performance of deep learning models for medical image analysis often decreases on images collected with different devices for data acquisition, device settings, or patient population. A better understanding of the…

计算机视觉与模式识别 · 计算机科学 2023-07-20 Aleksandar Vakanski , Min Xian

The ROC curve and the corresponding AUC are popular tools for the evaluation of diagnostic tests. They have been recently extended to assess prognostic markers and predictive models. However, due to the many particularities of time-to-event…

统计方法学 · 统计学 2012-10-26 Paul Blanche , Aurélien Latouche , Vivian Viallon

The precision of contouring target structures and organs-at-risk (OAR) in radiotherapy planning is crucial for ensuring treatment efficacy and patient safety. Recent advancements in deep learning (DL) have significantly improved OAR…

图像与视频处理 · 电气工程与系统科学 2024-09-30 Marvin Tom Teichmann , Manasi Datar , Lisa Kratzke , Fernando Vega , Florin C. Ghesu

Background: Chest X-rays are the most commonly performed, cost-effective diagnostic imaging tests ordered by physicians. A clinically validated AI system that can reliably separate normals from abnormals can be invaluble particularly in…

Background: With the ever-increasing amount of medical imaging data, the demand for algorithms to assist clinicians has amplified. Unsupervised anomaly detection (UAD) models promise to aid in the crucial first step of disease detection.…

Receiver Operating Characteristic (ROC) curves are plots of true positive rate versus false positive rate which are useful for evaluating binary classification models, but difficult to use for learning since the Area Under the Curve (AUC)…

机器学习 · 统计学 2021-07-06 Jonathan Hillman , Toby Dylan Hocking

Adequate evaluation of an information retrieval system to estimate future performance is a crucial task. Area under the ROC curve (AUC) is widely used to evaluate the generalization of a retrieval system. However, the objective function…

信息检索 · 计算机科学 2016-04-26 Sean J. Welleck

Two different approaches to analysis of data from diagnostic biomarker studies are commonly employed. Logistic regression is used to fit models for probability of disease given marker values, while ROC curves and risk distributions are used…

应用统计 · 统计学 2013-12-02 Ying Huang , Margaret S. Pepe , Ziding Feng

Pancreatic ductal adenocarcinoma (PDAC) segmentation on contrast-enhanced CT is inherently ambiguous: inter-rater disagreement among experts reflects genuine uncertainty rather than annotation noise. Standard deep learning approaches assume…

机器学习 · 计算机科学 2026-05-19 Tristan Kirscher , Alexandra Ertl , Klaus Maier-Hein , Xavier Coubez , Philippe Meyer , Sylvain Faisan