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相关论文: Estimating Vaccine Efficacy Over Time After a Rand…

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In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

种群与进化 · 定量生物学 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

The Coronavirus 2019 (Covid-19) pandemic caused by the SARS-CoV-2 virus represents an unprecedented crisis for our planet. It is a bane of the \"uber connected world that we live in that this virus has affected almost all countries and…

Since the recent introduction of several viable vaccines for SARS-CoV-2, vaccination uptake has become the key factor that will determine our success in containing the COVID-19 pandemic. We argue that game theory and social network models…

In light of the continuing emergence of new SARS-CoV-2 variants and vaccines, we create a simulation framework for exploring possible infection trajectories under various scenarios. The situations of primary interest involve the interaction…

种群与进化 · 定量生物学 2022-01-10 Kory D. Johnson , Annemarie Grass , Daniel Toneian , Mathias Beiglböck , Jitka Polechová

Combating the SARS-CoV2 pandemic will require the fast development of effective preventive vaccines. Regulatory agencies may open accelerated approval pathways for vaccines if an immunological marker can be established as a mediator of a…

统计方法学 · 统计学 2021-03-05 David Benkeser , Iván Díaz , Jialu Ran

Considering the global pandemic of coronavirus disease 2019 (COVID-19), around the world several vaccines are being developed. Till now, these vaccines are the most effective way to reduce the high burden on the global health…

物理与社会 · 物理学 2023-02-22 Dibyajyoti Mallick , Aniruddha Ray , Ankita Das , Sayantari Ghosh

Population-wide vaccination is critical for containing the SARS-CoV-2 (Covid-19) pandemic when combined with restrictive and prevention measures. In this study, we introduce SAIVR, a mathematical model able to forecast the Covid-19 epidemic…

种群与进化 · 定量生物学 2022-01-19 Mattia Angeli , Georgios Neofotistos , Marios Mattheakis , Efthimios Kaxiras

Incorporating vaccination into mathematical models appears deceptively simple: models integrate vaccine-derived protections, such as reduced susceptibility to infection, using parameters informed by empirical estimates of vaccine efficacy…

种群与进化 · 定量生物学 2026-05-19 Casey E. Middleton , Oliver Eales , James M. McCaw , Freya M. Shearer

By the end of 2020, a year since the first cases of infection by the Covid-19 virus have been reported, there is a light at the end of the tunnel. Several pharmaceutical companies made significant progress in developing effective vaccines…

种群与进化 · 定量生物学 2021-08-04 Hilla De-Leon , Francesco Pederiva

COVID-19 will be a continuous threat to human population despite having a few vaccines at hand until we reach the endemic state through natural herd immunity and total immunization through universal vaccination. However, the vaccine acts as…

种群与进化 · 定量生物学 2022-08-26 V. R. Saiprasad , R. Gopal , V. K. Chandrasekar , M. Lakshmanan

The effectiveness of vaccination highly depends on the choice of individuals to vaccinate, even if the same number of individuals are vaccinated. Vaccinating individuals with high centrality measures such as betweenness centrality (BC) and…

物理与社会 · 物理学 2021-12-30 Bukyoung Jhun

The test-negative design has become popular for evaluating the effectiveness of post-licensure vaccines using observational data. In addition to its logistical convenience on data collection, the design is also believed to control for the…

统计方法学 · 统计学 2026-05-15 Soumyabrata Kundu , Peng Ding , Jingshu Wang , Xinran Li

In vaccine studies for infectious diseases such as human immunodeficiency virus (HIV), the frequency and type of contacts between study participants and infectious sources are among the most informative risk factors, but are often not…

应用统计 · 统计学 2012-08-27 Yang Yang , Peter Gilbert , Ira M. Longini, , M. Elizabeth Halloran

In controlling transmission of COVID-19, the effectiveness of border quarantine strategies is a key concern for jurisdictions in which the local prevalence of disease and immunity is low. In settings like this such as China, Australia, and…

The advent and subsequent widespread availability of preventive vaccines has altered the course of public health over the past century. Despite this success, effective vaccines to prevent many high-burden diseases, including HIV, have been…

统计方法学 · 统计学 2020-11-17 Nima S. Hejazi , Mark J. van der Laan , Holly E. Janes , Peter B. Gilbert , David C. Benkeser

The COVID-19 pandemic has led to a need for widespread and rapid vaccine development. As several vaccines have recently been approved for human use or are in different stages of development, governments across the world are preparing…

The Covid-19 pandemic revealed the difficulties of vaccinating a population under the circumstances marked by urgency and limited availability of doses while balancing benefits associated with distinct guidelines satisfying specific ethical…

定量方法 · 定量生物学 2023-06-08 Pedro Ribeiro de Almeida , Vitor Hirata Sanches , Carla Goldman

The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics. This can be made possible with skilled experimental analyses and…

其他定量生物学 · 定量生物学 2012-06-06 Baby Jerald , T. R. Gopalakrishnan Nair

There are many sources of data giving information about the number of SARS-CoV-2 infections in the population, but all have major drawbacks, including biases and delayed reporting. For example, the number of confirmed cases largely…

应用统计 · 统计学 2022-06-08 Nicholas J. Irons , Adrian E. Raftery

The COVID-19 pandemic has influenced the lives of people globally. In the past year many researchers have proposed different models and approaches to explore in what ways the spread of the disease could be mitigated. One of the models that…

种群与进化 · 定量生物学 2021-06-17 Aram Ansary Ogholbake , Hana Khamfroush