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We address the challenge of conducting inference for a categorical treatment effect related to a binary outcome variable while taking into account high-dimensional baseline covariates. The conventional technique used to establish…

统计方法学 · 统计学 2024-11-27 Abhishek Ojha , Naveen N. Narisetty

Regression models with both high-dimensional responses and covariates have attracted growing attention. Standard multivariate regression models become inadequate when the response variables depend not only on observed covariates but also on…

统计方法学 · 统计学 2026-05-01 Jing Ouyang , Chengyu Cui , Yunxiao Chen , Kean Ming Tan , Gongjun Xu

The sequential treatment decisions made by physicians to treat chronic diseases are formalized in the statistical literature as dynamic treatment regimes. To date, methods for dynamic treatment regimes have been developed under the…

统计方法学 · 统计学 2022-02-22 Janie Coulombe , Erica E. M. Moodie , Susan M. Shortreed , Christel Renoux

Recent methodological developments have introduced new black-box approaches to better estimate heterogeneous treatment effects; however, these methods fall short of providing interpretable characterizations of the underlying individuals who…

统计方法学 · 统计学 2025-08-19 Melody Huang , Tiffany M. Tang , Ana M. Kenney

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated…

统计方法学 · 统计学 2026-04-06 Jianan Zhu , Jeffrey Zhang , Zijian Guo , Siyu Heng

Integrating multiple observational studies to make unconfounded causal or descriptive comparisons of group potential outcomes in a large natural population is challenging. Moreover, retrospective cohorts, being convenience samples, are…

统计方法学 · 统计学 2024-07-19 Subharup Guha , Yi Li

Empirical studies using Regression Discontinuity (RD) designs often explore heterogeneous treatment effects based on pretreatment covariates, even though no formal statistical methods exist for such analyses. This has led to the widespread…

计量经济学 · 经济学 2025-07-08 Sebastian Calonico , Matias D. Cattaneo , Max H. Farrell , Filippo Palomba , Rocio Titiunik

Various methods have recently been proposed to estimate causal effects with confidence intervals that are uniformly valid over a set of data generating processes when high-dimensional nuisance models are estimated by post-model-selection or…

统计方法学 · 统计学 2025-10-07 Niloofar Moosavi , Tetiana Gorbach , Xavier de Luna

With the rapid development of data collection and aggregation technologies in many scientific disciplines, it is becoming increasingly ubiquitous to conduct large-scale or online regression to analyze real-world data and unveil real-world…

统计方法学 · 统计学 2021-03-22 Jinfeng Xu , Zhiliang Ying , Na Zhao

Flexible estimation of heterogeneous treatment effects lies at the heart of many statistical challenges, such as personalized medicine and optimal resource allocation. In this paper, we develop a general class of two-step algorithms for…

机器学习 · 统计学 2020-08-07 Xinkun Nie , Stefan Wager

A key challenge in building effective regression models for large and diverse populations is accounting for patient heterogeneity. An example of such heterogeneity is in health system risk modeling efforts where different combinations of…

统计方法学 · 统计学 2022-12-26 Jared D. Huling , Menggang Yu

Methods for extending -- generalizing or transporting -- inferences from a randomized trial to a target population involve conditioning on a large set of covariates that is sufficient for rendering the randomized and non-randomized groups…

统计方法学 · 统计学 2021-10-04 Sarah E Robertson , Jon A Steingrimsson , Issa J Dahabreh

To estimate casual treatment effects, we propose a new matching approach based on the reduced covariates obtained from sufficient dimension reduction. Compared to the original covariates and the propensity score, which are commonly used for…

统计方法学 · 统计学 2017-02-03 Wei Luo , Yeying Zhu

The identification of influential observations is an important part of data analysis that can prevent erroneous conclusions drawn from biased estimators. However, in high dimensional data, this identification is challenging. Classical and…

Subgroup discovery is a local pattern mining technique to find interpretable descriptions of sub-populations that stand out on a given target variable. That is, these sub-populations are exceptional with regard to the global distribution.…

数据库 · 计算机科学 2017-09-26 Janis Kalofolias , Mario Boley , Jilles Vreeken

We address the problem of counterfactual regression using causal inference (CI) in observational studies consisting of high dimensional covariates and high cardinality treatments. Confounding bias, which leads to inaccurate treatment effect…

统计方法学 · 统计学 2021-04-12 Ankit Sharma , Garima Gupta , Ranjitha Prasad , Arnab Chatterjee , Lovekesh Vig , Gautam Shroff

Causal inference with observational studies often relies on the assumptions of unconfoundedness and overlap of covariate distributions in different treatment groups. The overlap assumption is violated when some units have propensity scores…

统计方法学 · 统计学 2022-07-19 Shu Yang , Peng Ding

Unobserved confounding is one of the main challenges when estimating causal effects. We propose a causal reduction method that, given a causal model, replaces an arbitrary number of possibly high-dimensional latent confounders with a single…

机器学习 · 统计学 2023-02-24 Maximilian Ilse , Patrick Forré , Max Welling , Joris M. Mooij

It is in general challenging to provide confidence intervals for individual variables in high-dimensional regression without making strict or unverifiable assumptions on the design matrix. We show here that a "group-bound" confidence…

统计方法学 · 统计学 2014-06-12 Nicolai Meinshausen

Observational studies are valuable tools for inferring causal effects in the absence of controlled experiments. However, these studies may be biased due to the presence of some relevant, unmeasured set of covariates. One approach to…

统计方法学 · 统计学 2026-02-17 William Bekerman , Abhinandan Dalal , Carlo del Ninno , Dylan S. Small
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