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Precision medicine requires the precision disease risk prediction models. In literature, there have been a lot well-established (inter-)national risk models, but when applying them into the local population, the prediction performance…

人工智能 · 计算机科学 2017-08-01 Jing Mei , Eryu Xia , Xiang Li , Guotong Xie

Machine learning models for chronic kidney disease (CKD) risk prediction often post strong discrimination scores on internal test sets. Calibration and uncertainty quantification get far less attention, leaving clinicians without reliable…

机器学习 · 计算机科学 2026-05-22 Michael O. Eniolade

Objective: Epileptic seizures are relatively common in critically-ill children admitted to the pediatric intensive care unit (PICU) and thus serve as an important target for identification and treatment. Most of these seizures have no…

Collaborative AI systems aim at working together with humans in a shared space to achieve a common goal. This setting imposes potentially hazardous circumstances due to contacts that could harm human beings. Thus, building such systems with…

软件工程 · 计算机科学 2021-03-15 Matteo Camilli , Michael Felderer , Andrea Giusti , Dominik T. Matt , Anna Perini , Barbara Russo , Angelo Susi

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

机器学习 · 计算机科学 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

Assessing acute brain dysfunction (ABD), including delirium and coma in the intensive care unit (ICU), is a critical challenge due to its prevalence and severe implications for patient outcomes. Current diagnostic methods rely on infrequent…

Hyperkalemia is a potentially life-threatening condition that can lead to fatal arrhythmias. Early identification of high risk patients can inform clinical care to mitigate the risk. While hyperkalemia is often a complication of acute…

机器学习 · 计算机科学 2021-01-28 Gloria Hyunjung Kwak , Christina Chen , Lowell Ling , Erina Ghosh , Leo Anthony Celi , Pan Hui

Although general-purpose AI systems offer transformational opportunities in science and industry, they simultaneously raise critical concerns about safety, misuse, and potential loss of control. Despite these risks, methods for assessing…

Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

计算与语言 · 计算机科学 2025-08-28 Jun Hou , Lucy Lu Wang

This study compares the efficacy of GPT-4 and clinalytix Medical AI in predicting the clinical risk of delirium development. Findings indicate that GPT-4 exhibited significant deficiencies in identifying positive cases and struggled to…

计算与语言 · 计算机科学 2024-09-17 Mohamed Rezk , Patricia Cabanillas Silva , Fried-Michael Dahlweid

In this work, we propose a multi-task recurrent neural network with attention mechanism for predicting cardiovascular events from electronic health records (EHRs) at different time horizons. The proposed approach is compared to a standard…

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

机器学习 · 计算机科学 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

软件工程 · 计算机科学 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung

Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine…

机器学习 · 统计学 2019-08-13 Hrayr Harutyunyan , Hrant Khachatrian , David C. Kale , Greg Ver Steeg , Aram Galstyan

Progression to dialysis or end-stage renal disease is a rare but clinically important outcome. Clinicians need evidence on how medication exposures influence downstream risk. We constructed a fixed-window EHR cohort (90-day observation,…

机器学习 · 计算机科学 2026-04-28 Kalyani P. Pande , Evan Yang , Bryan Zhu , Sandeep K. Mallipattu , Alisa Yurovsky , Tengfei Ma

Intensive care clinicians need reliable clinical practice tools to preempt unexpected critical events that might harm their patients in intensive care units (ICU), to pre-plan timely interventions, and to keep the patient's family well…

Artificial intelligence holds strong potential to support clinical decision making in intensive care units where timely and accurate risk assessment is critical. However, many existing models focus on isolated outcomes or limited data…

The prevalence of dementia has increased over time as global life expectancy improves and populations age. An individual's risk of developing dementia is influenced by various genetic, lifestyle, and environmental factors, among others.…

神经元与认知 · 定量生物学 2024-01-12 Srilekha Mamidala

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

应用统计 · 统计学 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

Hospitals lack automated systems to harness the growing volume of heterogeneous clinical and operational data to effectively forecast critical events. Early identification of patients at risk for deterioration is essential not only for…