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Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

种群与进化 · 定量生物学 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

In this article, we consider an HIV/AIDS epidemic model with four classes of individuals. We have discussed about basic properties of the system and found the basic reproduction number $R_0$ of the system. The stability analysis of the…

动力系统 · 数学 2023-04-18 Nouar Chorfi , Salem Abdelmalek , Samir Bendoukha

Human behaviour strongly influences the spread of infectious diseases: understanding the interplay between epidemic dynamics and adaptive behaviours is essential to improve response strategies to epidemics, with the goal of containing the…

物理与社会 · 物理学 2024-08-21 Marco Mancastroppa , Alessandro Vezzani , Vittoria Colizza , Raffaella Burioni

In this article we propose a compartmental model for the dynamics of Coronavirus Disease 2019 (COVID-19). We take into account the presence of asymptomatic infections and the main policies that have been adopted so far to contain the…

种群与进化 · 定量生物学 2020-05-18 M. Soledad Aronna , Roberto Guglielmi , Lucas M. Moschen

In this paper, we consider an adaptive optimal control problem for an SIR/V epidemic model with human behavioral effects.We develop a model where effective management of infectious diseases are monitored by the means of non pharmaceutical…

物理与社会 · 物理学 2025-12-09 Nuruzzaman Rahat , Abid Hossain , Muntasir Alam

Early detection and isolation of COVID-19 patients are essential for successful implementation of mitigation strategies and eventually curbing the disease spread. With a limited number of daily COVID-19 tests performed in every country,…

定量方法 · 定量生物学 2022-06-15 Mohammed Alser , Jeremie S. Kim , Nour Almadhoun Alserr , Stefan W. Tell , Onur Mutlu

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

种群与进化 · 定量生物学 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde

A reasonable prediction of infectious diseases transmission process under different disease control strategies is an important reference point for policy makers. Here we established a dynamic transmission model via Python and realized…

种群与进化 · 定量生物学 2021-02-23 Yuxuan Zhang , Chen Gong , Dawei Li , Zhi-Wei Wang , Shengda D Pu , Alex W Robertson , Hong Yu , John Parrington

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

This paper investigates a behavioral-feedback SIR model in which the infection rate adapts dynamically based on the fractions of susceptible and infected individuals. We introduce an invariant of motion and we characterize the peak of…

种群与进化 · 定量生物学 2025-09-17 Martina Alutto , Leonardo Cianfanelli , Giacomo Como , Fabio Fagnani , Francesca Parise

The impact of mitigation or control measures on an epidemics can be estimated by fitting the parameters of a compartmental model to empirical data, and running the model forward with modified parameters that account for a specific measure.…

种群与进化 · 定量生物学 2020-04-10 Jacopo Grilli , Matteo Marsili , Guido Sanguinetti

Since early 2020, the world has been dealing with a raging pandemic outbreak: COVID-19. A year later, vaccines have become accessible, but in limited quantities, so that governments needed to devise a strategy to decide which part of the…

种群与进化 · 定量生物学 2022-04-13 Sander Tonkens , Paul de Klaver , Mauro Salazar

Long-term care facilities have been widely affected by the COVID-19 pandemic. Retirement homes are particularly vulnerable due to the higher mortality risk of infected elderly individuals. Once an outbreak occurs, suppressing the spread of…

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

最优化与控制 · 数学 2020-12-22 Hailiang Liu , Xuping Tian

We propose a dynamical model for describing the spread of epidemics. This model is an extension of the SIQR (susceptible-infected-quarantined-recovered) and SIRP (susceptible-infected-recovered-pathogen) models used earlier to describe…

物理与社会 · 物理学 2022-12-08 S. P. Lukyanets , I. S. Gandzha , O. V. Kliushnichenko

Although modeling studies are focused on the control of SIR-based systems describing epidemic data sets (particularly the COVID-19), few of them present a formal dynamic characterization in terms of equilibrium sets and stability. Such…

最优化与控制 · 数学 2021-06-03 A. H. González , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas

Mathematical models are instrumental to forecast the spread of pathogens and to evaluate the effectiveness of non-pharmaceutical measures. A plethora of optimal strategies has been recently developed to minimize either the infected peak…

动力系统 · 数学 2021-11-11 J. Sereno , A. L. Anderson , A. Ferramosca , E. A. Hernandez-Vargas , A. H. Gonzalez

The Omicron wave was the largest wave of COVID-19 pandemic to date, more than doubling any other in terms of cases and hospitalizations in the United States. In this paper, we present a large-scale agent-based model of policy interventions…

社会与信息网络 · 计算机科学 2023-01-20 David O'Gara , Samuel F. Rosenblatt , Laurent Hébert-Dufresne , Rob Purcell , Matt Kasman , Ross A. Hammond

During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

最优化与控制 · 数学 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

Motivated by COVID-19, we develop and analyze a simple stochastic model for a disease spread in human population. We track how the number of infected and critically ill people develops over time in order to estimate the demand that is…

种群与进化 · 定量生物学 2022-05-10 Jakub Svoboda , Josef Tkadlec , Andreas Pavlogiannis , Krishnendu Chatterjee , Martin A. Nowak