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Dynamic Causal Modeling (DCM) is a Bayesian framework for inferring on hidden (latent) neuronal states, based on measurements of brain activity. Since its introduction in 2003 for functional magnetic resonance imaging data, DCM has been…

定量方法 · 定量生物学 2021-04-08 Inês Pereira , Stefan Frässle , Jakob Heinzle , Dario Schöbi , Cao Tri Do , Moritz Gruber , Klaas E. Stephan

This paper introduces a novel approach for modelling time-varying connectivity in neuroimaging data, focusing on the slow fluctuations in synaptic efficacy that mediate neuronal dynamics. Building on the framework of Dynamic Causal…

神经元与认知 · 定量生物学 2024-12-05 Johan Medrano , Karl J. Friston , Peter Zeidman

Effective connectivity analysis in functional magnetic resonance imaging (fMRI) studies directional interactions among brain regions and experimental stimuli. Dynamic causal modeling (DCM) is a widely used method to estimate effective…

统计方法学 · 统计学 2026-05-15 Kaitlyn R. Fales , Hyebin Song , Nicole A. Lazar

This technical note introduces parametric dynamic causal modelling, a method for inferring slow changes in biophysical parameters that control fluctuations of fast neuronal states. The application domain we have in mind is inferring slow…

定量方法 · 定量生物学 2020-08-27 Amirhossein Jafarian , Peter Zeidman , Rob. C Wykes , Matthew Walker , Karl J. Friston

This paper explores the discrete Dynamic Causal Modeling (DDCM) and its relationship with Directed Information (DI). We prove the conditional equivalence between DDCM and DI in characterizing the causal relationship between two brain…

神经元与认知 · 定量生物学 2017-09-20 Zhe Wang , Yu Zheng , David C. Zhu , Jian Ren , Tongtong Li

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

信号处理 · 电气工程与系统科学 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

We present a didactic introduction to spectral Dynamic Causal Modelling (DCM), a Bayesian state-space modelling approach used to infer effective connectivity from non-invasive neuroimaging data. Spectral DCM is currently the most widely…

神经元与认知 · 定量生物学 2023-09-07 Leonardo Novelli , Karl Friston , Adeel Razi

Deep Markov models (DMM) are generative models that are scalable and expressive generalization of Markov models for representation, learning, and inference problems. However, the fundamental stochastic stability guarantees of such models…

机器学习 · 计算机科学 2021-11-09 Ján Drgoňa , Sayak Mukherjee , Jiaxin Zhang , Frank Liu , Mahantesh Halappanavar

Physics Informed Neural Networks is a numerical method which uses neural networks to approximate solutions of partial differential equations. It has received a lot of attention and is currently used in numerous physical and engineering…

数值分析 · 数学 2025-07-10 Dimitrios Gazoulis , Ioannis Gkanis , Charalambos G. Makridakis

"Dynamic compensation" is a robustness property where a perturbed biological circuit maintains a suitable output [Karin O., Swisa A., Glaser B., Dor Y., Alon U. (2016). Mol. Syst. Biol., 12: 886]. In spite of several attempts, no fully…

系统与控制 · 计算机科学 2018-01-17 Michel Fliess , Cédric Join

Dynamical compensation (DC) provides robustness to parameter fluctuations. As an example, DC enable control of the functional mass of endocrine or neuronal tissue essential for controlling blood glucose by insulin through a nonlinear…

系统与控制 · 电气工程与系统科学 2024-06-04 Akram Ashyani , Yu-Heng Wu , Huan-Wei Hsu , Torbjörn E. M. Nordling

This work concerns the application of physics-informed neural networks to the modeling and control of complex robotic systems. Achieving this goal required extending Physics Informed Neural Networks to handle non-conservative effects. We…

机器人学 · 计算机科学 2023-07-07 Jingyue Liu , Pablo Borja , Cosimo Della Santina

In view of ever-changing conditions both in the external world and in intrinsic brain states, maintaining the robustness of computations poses a challenge, adequate solutions to which we are only beginning to understand. At the level of…

神经元与认知 · 定量生物学 2022-03-29 Nelson Niemeyer , Jan-Hendrik Schleimer , Susanne Schreiber

Dynamic Causal Modelling (DCM) is the predominant method for inferring effective connectivity from neuroimaging data. In the 15 years since its introduction, the neural models and statistical routines in DCM have developed in parallel,…

This paper establishes fundamental results for statistical inference of diagnostic classification models (DCM). The results are developed at a high level of generality, applicable to essentially all diagnostic classification models. In…

统计理论 · 数学 2025-01-08 Guanhua Fang , Jingchen Liu , Zhiliang Ying

We present a causal view on the robustness of neural networks against input manipulations, which applies not only to traditional classification tasks but also to general measurement data. Based on this view, we design a deep causal…

机器学习 · 计算机科学 2021-02-11 Cheng Zhang , Kun Zhang , Yingzhen Li

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Stability is a fundamental property of dynamical systems, yet to this date it has had little bearing on the practice of recurrent neural networks. In this work, we conduct a thorough investigation of stable recurrent models. Theoretically,…

机器学习 · 计算机科学 2019-03-05 John Miller , Moritz Hardt

Dynamics of a chaotic spiking neuron model are being studied mathematically and experimentally. The Nonlinear Dynamic State neuron (NDS) is analysed to further understand the model and improve it. Chaos has many interesting properties such…

人工智能 · 计算机科学 2013-10-29 Mohammad Alhawarat , Waleed Nazih , Mohammad Eldesouki

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

定量方法 · 定量生物学 2019-09-27 Po-Ya Hsu
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