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For the description of a pandemic mathematical models could be interesting. Both for physicians and politicians as a base for decisions to treat the disease. The responsible estimation of parameters is a main issue of mathematical pandemic…

种群与进化 · 定量生物学 2020-04-15 Günter Bärwolff

During an infectious disease outbreak, biases in the data and complexities of the underlying dynamics pose significant challenges in mathematically modelling the outbreak and designing policy. Motivated by the ongoing response to COVID-19,…

We model further development of the COVID-19 epidemic in the UK given the current data and assuming different scenarios of handling the epidemic. In this research, we further extend the stochastic model suggested in \cite{us} and…

种群与进化 · 定量生物学 2020-04-10 Anatoly Zhigljavsky , Roger Whitaker , Ivan Fesenko , Kobi Kremnizer , Jack Noonan

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

最优化与控制 · 数学 2020-12-22 Hailiang Liu , Xuping Tian

Objectives. Public health officials need tools to assist with anticipating the healthcare resources required to confront the SARS-COV-2 pandemic. We built a modeling tool to aid practicing public health officials with estimating healthcare…

种群与进化 · 定量生物学 2020-05-14 Gabriel Rainisch , Eduardo A. Undurraga , Gerardo Chowell

Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

This contribution analyzes the COVID-19 outbreak by comparably simple mathematical and numerical methods. The final goal is to predict the peak of the epidemic outbreak per country with a reliable technique. This is done by an algorithm…

物理与社会 · 物理学 2020-05-15 Robert Schaback

In the wake of COVID-19, every government huddles to find the best interventions that will reduce the number of infection cases while minimizing the economic impact. However, with many intervention policies available, how should one decide…

最优化与控制 · 数学 2021-04-19 Chang Liu , Akshay Budhkar

The current global health emergency triggered by the pandemic COVID-19 is one of the greatest challenges mankind face in this generation. Computational simulations have played an important role to predict the development of the current…

种群与进化 · 定量生物学 2020-06-11 Kok Yew Ng , Meei Mei Gui

In this paper we propose a data-driven model for the spread of SARS-CoV-2 and use it to design optimal control strategies of human-mobility restrictions that both curb the epidemic and minimize the economic costs associated with…

最优化与控制 · 数学 2021-05-21 Mikhail Hayhoe , Francisco Barreras , Victor M. Preciado

Globally, the outbreaks of infectious diseases have exerted an extremely profound and severe influence on health security and the economy. During the critical phases of epidemics, devising effective intervention measures poses a significant…

机器学习 · 计算机科学 2025-05-08 Baida Zhang , Yakai Chen , Huichun Li , Zhenghu Zu

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

应用统计 · 统计学 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

The dramatic outbreak of the coronavirus disease 2019 (COVID-19) pandemics and its ongoing progression boosted the scientific community's interest in epidemic modeling and forecasting. The SIR (Susceptible-Infected-Removed) model is a…

种群与进化 · 定量生物学 2021-02-24 Dimiter Prodanov

In the context of epidemiology, policies for disease control are often devised through a mixture of intuition and brute-force, whereby the set of logically conceivable policies is narrowed down to a small family described by a few…

种群与进化 · 定量生物学 2021-10-04 Miguel Navascues , Costantino Budroni , Yelena Guryanova

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

Various non pharmaceutical interventions have been settled to minimise the burden of the COVID-19 outbreak. We build a framework to analyse the dynamics of non pharmaceutical interventions, to distinguish between mitigations measures…

种群与进化 · 定量生物学 2023-01-23 Laurent Evain , Jean-Jacques Loeb

In this research, we develop a framework to analyze the interaction between the economy and the Covid-19 pandemic using an extension of SIR epidemic model. At the outset, we assume there are two health related investments including general…

最优化与控制 · 数学 2022-02-14 Zachariah Sinkala , Vajira Manathunga , Bichaka Fayissa

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

统计方法学 · 统计学 2023-06-26 Chih-Li Sung , Ying Hung

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

种群与进化 · 定量生物学 2020-09-14 Amit Tewari
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