相关论文: Peristaltic pumping in sub-wavelength channels
Peristaltic pumping is hypothesized to drive fluid transport in several physiological systems, including cerebrospinal fluid flow through cerebral perivascular spaces (PVSs). Cerebral PVSs are unique in the context of peristaltic pumping…
A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…
Two-dimensional laminar flow of a viscous fluid induced by peristalsis due to a moving wall wave has been studied previously for a rectangular channel, a circular tube, and a concentric circular annulus. Here we study peristaltic flow in a…
Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…
Previous studies on peristalsis, the pumping of fluid along a channel by wave-like displacements of the channel walls, have shown that the elastic properties of the channel and the peristaltic wave shape can influence the flow rate.…
Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…
The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that…
The paper deals with a theoretical investigation of the peristaltic transport of a physiological fluid in a porous asymmetric channel under the action of a magnetic field. The stream function, pressure gradient and axial velocity are…
Immersed nonlinear elements are prevalent in biological systems that require a preferential flow direction, such as the venous and the lymphatic system. We investigate here a certain class of models where the fluid is driven by peristaltic…
Of concern in this paper is an investigation of peristaltic transport of a physiological fluid in an asymmetric channel under long wave length and low-Reynolds number assumptions. The flow is assumed to be incompressible, viscous,…
Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…
Peristalsis is the driving mechanism behind a broad array of biological and engineered flows. In peristaltic pumping, a wave-like contraction of the tube wall produces local changes in volume which induce flow. Net flow arises due to…
Low Reynolds number flow near a poroelastic interface can be found across scales in biological and engineered systems. We develop a 2D model of peristaltic flow confined under a poroelastic solid. In this geometry, the lower boundary is an…
The dynamic flow of cerebrospinal fluid (CSF) in brain ventricles exhibits flow features on several scales, both spatially and temporally. Most analysis of this complex flow and the accompanying transport has used instantaneous (Eulerian)…
Cerebrospinal fluid (CSF) plays a pivotal role in normal functioning of Brain. Intracranial compartments such as blood, brain and CSF are incompressible in nature. Therefore, if a volume imbalance in one of the aforenoted compartments is…
This paper addresses the pulsating motion of cerebrospinal fluid in the aqueduct of Sylvius, a slender canal connecting the third and fourth ventricles of the brain. Specific attention is given to the relation between the instantaneous…
Numerous mathematical models have emerged in the medical literature over the past two decades attempting to characterize the pressure and volume dynamics the central nervous system compartment. These models have been used to study he…
The paper is devoted to a study of the peristaltic motion of blood in the micro-circulatory system. The vessel is considered to be of varying cross-section. The progressive peristaltic waves are taken to be of sinusoidal nature. Blood is…
Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…
This paper considers particle propagation in a cylindrical molecular communication channel, e.g. a simplified model of a blood vessel. Emitted particles are influenced by diffusion, flow, and a vertical force induced e.g. by gravity or…