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In this paper, we propose a propensity score adapted variable selection procedure to select covariates for inclusion in propensity score models, in order to eliminate confounding bias and improve statistical efficiency in observational…

统计方法学 · 统计学 2021-09-14 Kangjie Zhou , Jinzhu Jia

Regression discontinuity designs are frequently used to estimate the causal effect of election outcomes and policy interventions. In these contexts, treatment effects are typically estimated with covariates included to improve efficiency.…

应用统计 · 统计学 2020-05-06 L. Jason Anastasopoulos

Gun violence is a major source of injury and death in the United States. However, relatively little is known about the effects of firearm injuries on survivors and their family members and how these effects vary across subpopulations. To…

应用统计 · 统计学 2024-06-04 Eric R. Cohn , Zirui Song , Jose R. Zubizarreta

Causal mediation analysis seeks to determine whether an independent variable affects a response variable directly or whether it does so indirectly, by way of a mediator. The existing statistical tests to determine the existence of an…

统计方法学 · 统计学 2023-09-28 John Kidd , Dan-Yu Lin

In randomized clinical trials, adjustments for baseline covariates at both design and analysis stages are highly encouraged by regulatory agencies. A recent trend is to use a model-assisted approach for covariate adjustment to gain…

统计方法学 · 统计学 2021-07-14 Ting Ye , Jun Shao , Yanyao Yi , Qingyuan Zhao

Our goal is to produce methods for observational causal inference that are auditable, easy to troubleshoot, accurate for treatment effect estimation, and scalable to high-dimensional data. We describe a general framework called…

统计方法学 · 统计学 2023-10-16 Quinn Lanners , Harsh Parikh , Alexander Volfovsky , Cynthia Rudin , David Page

Recent advances in causal mediation analysis have formalized conditions for estimating direct and indirect effects in various contexts. These approaches have been extended to a number of models for survival outcomes including accelerated…

统计方法学 · 统计学 2017-01-11 Isabel R. Fulcher , Eric Tchetgen Tchetgen , Paige L. Williams

After selection with the Group LASSO (or generalized variants such as the overlapping, sparse, or standardized Group LASSO), inference for the selected parameters is unreliable in the absence of adjustments for selection bias. In the…

统计方法学 · 统计学 2022-08-16 Snigdha Panigrahi , Peter W. MacDonald , Daniel Kessler

This paper studies the multiplicity-correction effect of standard Bayesian variable-selection priors in linear regression. Our first goal is to clarify when, and how, multiplicity correction happens automatically in Bayesian analysis, and…

统计理论 · 数学 2010-11-11 James G. Scott , James O. Berger

We consider the problems of variable selection and estimation in nonparametric additive regression models for high-dimensional data. In recent years, several methods have been proposed to model nonlinear relationships when the number of…

统计方法学 · 统计学 2013-10-07 Linn Cecilie Bergersen , Kukatharmini Tharmaratnam , Ingrid K. Glad

The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings, offering an alternative to the commonly used…

统计方法学 · 统计学 2025-07-22 Jiren Sun , Tuo Wang , Yanyao Yi , Ting Ye , Jun Shao , Yu Du

There is a considerable literature in case-control logistic regression on whether or not non-confounding covariates should be adjusted for. However, only limited and ad hoc theoretical results are available on this important topic. A…

统计理论 · 数学 2023-05-19 Siliang Zhang , Jinbo Chen , Zhiliang Ying , Hong Zhang

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal…

统计方法学 · 统计学 2025-08-06 Wei Li , Jiapeng Liu , Peng Ding , Zhi Geng

Background: Choosing the most performing method in terms of outcome prediction or variables selection is a recurring problem in prognosis studies, leading to many publications on methods comparison. But some aspects have received little…

Observational studies can play a useful role in assessing the comparative effectiveness of competing treatments. In a clinical trial the randomization of participants to treatment and control groups generally results in well-balanced groups…

To estimate the causal effect of treatments that vary over time from observational data, one must adjust for time-varying confounding. A common procedure to address confounding is the use of inverse probability of treatment weighting…

统计方法学 · 统计学 2025-01-22 Wouter M. R. Kant , Jesse H. Krijthe

We propose robust methods for inference on the effect of a treatment variable on a scalar outcome in the presence of very many controls. Our setting is a partially linear model with possibly non-Gaussian and heteroscedastic disturbances.…

统计方法学 · 统计学 2017-10-05 Alexandre Belloni , Victor Chernozhukov , Christian Hansen

In the statistical literature, a number of methods have been proposed to ensure valid inference about marginal effects of variables on a longitudinal outcome in settings with irregular monitoring times. However, the potential biases due to…

统计方法学 · 统计学 2021-12-23 Janie Coulombe , Erica E M Moodie , Robert W Platt

Causal mediation analysis is used to evaluate direct and indirect causal effects of a treatment on an outcome of interest through an intermediate variable or a mediator.It is difficult to identify the direct and indirect causal effects…

应用统计 · 统计学 2020-01-14 Wei Li , Chunchen Liu , Zhi Geng , John Murray

The Difference in Difference (DiD) estimator is a popular estimator built on the "parallel trends" assumption, which is an assertion that the treatment group, absent treatment, would change "similarly" to the control group over time. To…

统计方法学 · 统计学 2024-02-09 Dae Woong Ham , Luke Miratrix