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Identifying how dependence relationships vary across different conditions plays a significant role in many scientific investigations. For example, it is important for the comparison of biological systems to see if relationships between…

统计方法学 · 统计学 2023-07-31 Hoseung Song , Michael C. Wu

Markov chain Monte Carlo samplers produce dependent streams of variates drawn from the limiting distribution of the Markov chain. With this as motivation, we introduce novel univariate kernel density estimators which are appropriate for the…

统计方法学 · 统计学 2016-07-29 Hang J. Kim , Steven N. MacEachern , Yoonsuh Jung

This paper is motivated by the comparison of genetic networks based on microarray samples. The aim is to test whether the differences observed between two inferred Gaussian graphical models come from real differences or arise from…

统计理论 · 数学 2014-06-20 Camille Charbonnier , Nicolas Verzelen , Fanny Villers

When there are resource constraints, it is important to rank or estimate treatment benefits according to patient characteristics. This facilitates prioritization of assigning different treatments. Most existing literature on individualized…

统计方法学 · 统计学 2021-05-05 Muxuan Liang , Menggang Yu

Deep learning approaches to the segmentation of magnetic resonance images have shown significant promise in automating the quantitative analysis of brain images. However, a continuing challenge has been its sensitivity to the variability of…

图像与视频处理 · 电气工程与系统科学 2021-03-05 Dzung L. Pham , Yi-Yu Chou , Blake E. Dewey , Daniel S. Reich , John A. Butman , Snehashis Roy

Global expression analyses using microarray technologies are becoming more common in genomic research, therefore, new statistical challenges associated with combining information from multiple studies must be addressed. In this paper we…

应用统计 · 统计学 2013-01-29 Jia Li , George C. Tseng

Data from multifactor HCI experiments often violates the normality assumption of parametric tests (i.e., nonconforming data). The Aligned Rank Transform (ART) is a popular nonparametric analysis technique that can find main and interaction…

统计方法学 · 统计学 2021-02-24 Lisa A. Elkin , Matthew Kay , James J. Higgins , Jacob O. Wobbrock

Adaptive designs have been proposed for clinical trials in which the nuisance parameters or alternative of interest are unknown or likely to be misspecified before the trial. Whereas most previous works on adaptive designs and mid-course…

统计方法学 · 统计学 2011-05-18 Jay Bartroff , Tze Leung Lai

A key feature of magnetic resonance (MR) imaging is its ability to manipulate how the intrinsic tissue parameters of the anatomy ultimately contribute to the contrast properties of the final, acquired image. This flexibility, however, can…

计算机视觉与模式识别 · 计算机科学 2018-11-20 Dzung L. Pham , Snehashis Roy

This paper considers the problem of testing many moment inequalities, where the number of moment inequalities ($p$) is possibly larger than the sample size ($n$). Chernozhukov et al. (2019) proposed asymptotic tests for this problem using…

统计理论 · 数学 2020-06-09 Nick Koning , Paul Bekker

We propose a new approach, the calibrated nonparametric scan statistic (CNSS), for more accurate detection of anomalous patterns in large-scale, real-world graphs. Scan statistics identify connected subgraphs that are interesting or…

统计方法学 · 统计学 2022-06-28 Chunpai Wang , Daniel B. Neill , Feng Chen

Multivariate matched proportions (MMP) data appears in a variety of contexts including post-market surveillance of adverse events in pharmaceuticals, disease classification, and agreement between care providers. It consists of multiple sets…

统计方法学 · 统计学 2023-05-08 Mark J. Meyer , Haobo Cheng , Katherine Hobbs Knutson

In this paper, we develop a systematic theory for high dimensional analysis of variance in multivariate linear regression, where the dimension and the number of coefficients can both grow with the sample size. We propose a new \emph{U}~type…

统计方法学 · 统计学 2023-01-12 Zhipeng Lou , Xianyang Zhang , Wei Biao Wu

We consider the problem of robustly detecting changepoints in the variability of a sequence of independent multivariate functions. We develop a novel changepoint procedure, called the functional Kruskal--Wallis for covariance (FKWC)…

统计方法学 · 统计学 2024-08-08 Kelly Ramsay , Shoja'eddin Chenouri

Estimation of genewise variance arises from two important applications in microarray data analysis: selecting significantly differentially expressed genes and validation tests for normalization of microarray data. We approach the problem by…

统计理论 · 数学 2010-11-11 Jianqing Fan , Yang Feng , Yue S. Niu

Estimating individualized treatment effects from longitudinal observational data is central to data-driven medicine, yet existing methods face a fundamental limitation: reducing confounding bias often suppresses clinically informative…

We study a new parametric approach for hidden discrete-time diffusion models. This method is based on contrast minimization and deconvolution and leads to estimate a large class of stochastic models with nonlinear drift and nonlinear…

统计理论 · 数学 2017-01-01 Salima El Kolei , Florian Pelgrin

It has been proposed that complex populations, such as those that arise in genomics studies, may exhibit dependencies among observations as well as among variables. This gives rise to the challenging problem of analyzing unreplicated…

机器学习 · 统计学 2018-06-08 Michael Hornstein , Roger Fan , Kerby Shedden , Shuheng Zhou

Marginal structural models have been increasingly used by analysts in recent years to account for confounding bias in studies with time-varying treatments. The parameters of these models are often estimated using inverse probability of…

统计方法学 · 统计学 2024-03-14 David Adenyo , Jason R. Guertin , Bernard Candas , Caroline Sirois , Denis Talbot

The propensity score analysis is one of the most widely used methods for studying the causal treatment effect in observational studies. This paper studies treatment effect estimation with the method of matching weights. This method…

统计方法学 · 统计学 2011-05-17 Liang Li