相关论文: Dendritic trafficking: synaptic scaling and struct…

Mounting evidence shows that oscillatory activity is widespread in cell signaling. Here we review some of this recent evidence, focusing on both the molecular mechanisms that potentially underlie such dynamical behavior, and the potential…

This work presents a novel means for understanding learning dynamics and scaling relations in neural networks. We show that certain measures on the spectrum of the empirical neural tangent kernel, specifically entropy and trace, yield…

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

How neurons integrate the myriad synaptic inputs scattered across their dendrites is a fundamental question in neuroscience. Multiple neurophysiological experiments have shown that dendritic non-linearities can have a strong influence on…

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

Transport is an important function in many network systems and understanding its behavior on biological, social, and technological networks is crucial for a wide range of applications. However, it is a property that is not well-understood…

Network remodeling, or adaptation, in the presence of periodically driven forcings has hereto remained largely unexplored, despite the fact that a broad class of biological transport networks, e.g. animal vasculature, depends on periodic…

It is widely accepted that the complex dynamics characteristic of recurrent neural circuits contributes in a fundamental manner to brain function. Progress has been slow in understanding and exploiting the computational power of recurrent…

We investigate the dynamics of two models of biological networks with purely suppressive interactions between the units; species interacting via niche competition and neurons via inhibitory synaptic coupling. In both of these cases,…

Efficient processing and transfer of information in neurons have been linked to noise-induced resonance phenomena such as coherence resonance (CR), and adaptive rules in neural networks have been mostly linked to two prevalent mechanisms:…

We propose a new model based on the Ising model with the aim to study synaptic plasticity phenomena in neural networks. It is today well established in biology that the synapses or connections between certain types of neurons are…

Learning and memory are acquired through long-lasting changes in synapses. In the simplest models, such synaptic potentiation typically leads to runaway excitation, but in reality there must exist processes that robustly preserve overall…

Deep learning has seen remarkable developments over the last years, many of them inspired by neuroscience. However, the main learning mechanism behind these advances - error backpropagation - appears to be at odds with neurobiology. Here,…

Standard Spiking Neural Network (SNN) models typically neglect metabolic constraints, treating neurons as energetically unconstrained components. We bridge this gap by implementing a conductance-based leaky integrate-and-fire (gLIF)…

It is shown that a Hopfield recurrent neural network exhibits a scaling regime, whose specific exponents depend on the number of parcels used and the decay length of the coupling strength. This scaling regime recovers the picture introduced…

Spiking networks that perform probabilistic inference have been proposed both as models of cortical computation and as candidates for solving problems in machine learning. However, the evidence for spike-based computation being in any way…

Based on existing data, we wish to put forward a biological model of motor system on the neuron scale. Then we indicate its implications in statistics and learning. Specifically, neuron firing frequency and synaptic strength are probability…

Spike timing dependent plasticity (STDP) is believed to play an important role in shaping the structure of neural circuits. Here we show that STDP generates effective interactions between synapses of different neurons, which were neglected…

Synaptic plasticity poses itself as a powerful method of self-regulated unsupervised learning in neural networks. A recent resurgence of interest has developed in utilizing Artificial Neural Networks (ANNs) together with synaptic plasticity…

Biological systems perform an astonishing array of dynamical processes -- including development and repair, regulation, behavior and motor control, sensing and signaling, and adaptation, among others. Powered by the transduction of stored…