Signaling oscillations: molecular mechanisms and functional roles
Cell Behavior
2022-04-15 v1 Biological Physics
Molecular Networks
Abstract
Mounting evidence shows that oscillatory activity is widespread in cell signaling. Here we review some of this recent evidence, focusing on both the molecular mechanisms that potentially underlie such dynamical behavior, and the potential advantages that signaling oscillations might have in cell function. The biological processes considered include tissue maintenance, embryonic development and wound healing. With the aid of mathematical modeling, we show that a common principle, namely delayed negative feedback, underpins this wide variety of phenomena.
Cite
@article{arxiv.2204.06802,
title = {Signaling oscillations: molecular mechanisms and functional roles},
author = {Pablo Casani-Galdon and Jordi Garcia-Ojalvo},
journal= {arXiv preprint arXiv:2204.06802},
year = {2022}
}
Comments
6 pages, 4 figures