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There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…

流体动力学 · 物理学 2018-03-12 Fardin Khalili , Peshala T. Gamage , Hansen Mansy

Background and Objective: The role of red blood cell dynamics is emphasised in certain cardiovascular diseases, and thus needs to be closely studied. A multiphase model of blood flow allows the resolution of locally varying density of red…

流体动力学 · 物理学 2021-10-07 Konstantinos G. Lyras , Jack Lee

Dense suspensions of soft colloidal particles display a broad range of physical and rheological properties which are still far from being fully understood. To elucidate the role of deformability on colloidal flow, we employ computer…

软凝聚态物质 · 物理学 2018-08-31 M. Foglino , A. N. Morozov , D. Marenduzzo

Microfluidics technology offers high efficiency of heat and mass transfer and low safety hazards compared to conventional multiphase processes. The multiphase flow in the microchannels is usually characterized as Taylor flow that includes…

流体动力学 · 物理学 2021-02-09 Behrouz Behdani , Hayder A. Alhameedi

In this work the computer modeling has been used to show that longer ligands allow biological cells (e.g., blood platelets) to withstand stronger flows after their adhesion to solid walls. Mechanistic model of polymer-mediated…

软凝聚态物质 · 物理学 2018-04-18 Aleksey V. Belyaev

Understanding the rolling and adhesion behavior of a cell on the vascular surface under viscous shear flow is important to better understand many biological processes. One of the important examples is the adhesion of the leukocytes onto…

生物物理 · 物理学 2019-10-02 Maryam Bagheri , Mohammadreza Azmoodeh

Impulsively generated focused jets play a significant role in various applications, including inkjet printing, needle-free drug delivery, and microfluidic devices. As the demand for generating jets and droplets from medium to highly viscous…

流体动力学 · 物理学 2025-08-20 Xianggang Cheng , Xiao-Peng Chen , Hang Ding , Chun-Yu Zhang , Haibao Hu , Laibing Jia

In this paper, we investigate the effect of boundary surface roughness on numerical simulations of incompressible fluid flow past a cylinder in two and three spatial dimensions furnished with slip boundary conditions. The governing…

流体动力学 · 物理学 2025-11-05 Matthias Maier , Peter Munch , Murtazo Nazarov

Three-dimensional, time-dependent direct simulations of step emulsification micro-devices highlight two essential mechanisms for droplet formation: first, the onset of an adverse pressure gradient driving a back-flow of the continuous phase…

计算物理 · 物理学 2020-06-22 Andrea Montessori , Marco Lauricella , Sauro Succi , Elad Stolovicki , David A. Weitz

The rheological characterisation of complex fluids is mostly performed under simple shear flow in rotational rheometers. Their modern commercial versions are extremely sensitive instruments which are able to provide very accurate…

流体动力学 · 物理学 2021-03-05 Ahmad Fakhari , Francisco J. Galindo-Rosales

Vascular access, such as arteriovenous grafts, is crucial for patients undergoing haemodialysis as part of kidney replacement therapy. One of the primary causes of arteriovenous graft failure and loss of patency is disordered blood flow, as…

组织与器官 · 定量生物学 2025-08-11 Guanqi Wang , Thomas Abadie , Ivan Wall , Patricia Pérez Esteban

This paper is an attempt to study the effects of surface topography on the flow of a droplet (or a bubble) in a low Reynolds number flow regime. Multiphase flows through a constricted passage find many interesting applications in chemistry…

流体动力学 · 物理学 2021-02-03 Aditya Singla , Bahni Ray

Shear flow of dense, non-Brownian suspensions is simulated using the discrete element method, taking particle contact and hydrodynamic lubrication into account. The resulting flow regimes are mapped in the parametric space of solid volume…

软凝聚态物质 · 物理学 2015-01-06 Christopher Ness , Jin Sun

The flow behaviors of polymer melt composed of short chains with ten beads between parallel plates are simulated by using a hybrid method of molecular dynamics and computational fluid dynamics. Three problems are solved: creep motion under…

软凝聚态物质 · 物理学 2014-01-20 Shugo Yasuda , Ryoichi Yamamoto

Platelet-enriched plasma and red blood cells (RBC) are needed in the treatment of blood-related diseases, including anaemia and blood cancer. These essential components must be separated from blood in well-designed experimental setups. If…

流体动力学 · 物理学 2026-03-16 Rishi Kumar , Indranil Saha Dalal , K. Muralidhar

Two-dimensional Particle Tracking Velocimetry (PTV) is a promising technique to study the behaviour of granular flows. The aim is to experimentally determine the free surface width and position of the shear band from the velocity profile to…

Subclinical leaflet thrombosis (SLT) is a potentially serious complication of aortic valve replacement with a bioprosthetic valve in which blood clots form on the replacement valve. SLT is associated with increased risk of transient…

Albeit the hemodynamics of artificial heart valves has been investigated for several decades, the local shear-induced activation potential and subsequent transport phenomena of activated platelets in different valve designs, which mediate…

流体动力学 · 物理学 2025-07-31 Syed Samar Abbas , Iman Borazjani

Buckling induced by viscous flow changes the shape of sheet-like nanomaterial particles suspended in liquids. This instability at the particle scale affects collective behavior of suspension flows and has many technological and biological…

流体动力学 · 物理学 2023-03-10 Hugo Perrin , Heng Li , Lorenzo Botto

We investigate the interface of a glass-forming fluid showing non-Newtonian rheology. By applying shear flow in the interface, we detect that the surface tension depends on the shear rate. Importantly, the standard way of determining…

软凝聚态物质 · 物理学 2025-08-12 Linnea Heitmeier , Thomas Voigtmann