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For chemical reaction networks described by a master equation, we define energy and entropy on a stochastic trajectory and develop a consistent nonequilibrium thermodynamic description along a single stochastic trajectory of reaction…

统计力学 · 物理学 2009-11-11 Tim Schmiedl , Udo Seifert

The ability to store continuous variables in the state of a biological system (e.g. a neural network) is critical for many behaviours. Most models for implementing such a memory manifold require hand-crafted symmetries in the interactions…

神经元与认知 · 定量生物学 2024-09-09 Tankut Can , Kamesh Krishnamurthy

The equilibration of enzyme and complex concentrations in deterministic Michaelis-Menten reaction networks underlies the hyperbolic dependence between the input (substrates) and output (products). This relationship was first obtained by…

分子网络 · 定量生物学 2024-09-30 Subham Pal , Manmath Panigrahy , R. Adhikari , Arti Dua

We construct a continuous-time, positively divisible non-Markovian process with memory of the initial state that satisfies the differential Chapman--Kolmogorov equation. In the stationary state, the correlation function exhibits exponential…

概率论 · 数学 2026-05-29 Bilal Canturk , Gokhan Baris Bagci , Onur Pusuluk

Spontaneous explosive emergent behavior takes place in heterogeneous networks when the frequencies of the nodes are positively correlated to the node degree. A central feature of such explosive transitions is a hysteretic behavior at the…

混沌动力学 · 物理学 2014-03-26 Yong Zou , Tiago Pereira , Michael Small , Zonghua Liu , Jürgen Kurths

Epigenetic cell memory, the inheritance of gene expression patterns across subsequent cell divisions, is a critical property of multi-cellular organisms. In recent work [10], a subset of the authors observed in a simulation study how the…

Applying the mathematical circulation theory of Markov chains, we investigate the synchronized stochastic dynamics of a discrete network model of yeast cell-cycle regulation where stochasticity has been kept rather than being averaged out.…

分子网络 · 定量生物学 2009-04-16 Hao Ge , Hong Qian , Min Qian

Multistability-induced hysteresis has been widely studied in mechanical systems, but such behavior has proven more difficult to reproduce experimentally in flow networks. Natural flow networks like animal and plant vasculature can exhibit…

软凝聚态物质 · 物理学 2025-12-03 Lauren E. Altman , Nadia Aguilar , Douglas J. Durian , Miguel Ruiz-Garcia , Eleni Katifori

Many biological, social and man-made systems are better described in terms of temporal networks, i.e. networks whose links are only present at certain points in time, rather than by static ones. In particular, it has been found that…

物理与社会 · 物理学 2019-05-22 Oliver E. Williams , Fabrizio Lillo , Vito Latora

Active systems across scales, ranging from molecular machines to human crowds, are usually modeled as assemblies of self-propelled particles driven by internally generated forces. However, these models often assume memoryless dynamics and…

统计力学 · 物理学 2025-12-10 Marc Besse , Raphaël Voituriez

A fluctuation theorem is examined for the first-passage time of a biomolecular machine (e.g., a motor protein or an enzyme) in a nonequilibrium steady-state. For such machines in which the driven, observable process is coupled to a hidden…

生物物理 · 物理学 2025-09-15 D. Evan Piephoff , Jianshu Cao

The characterisation of information processing is an important task in complex systems science. Information dynamics is a quantitative methodology for modelling the intrinsic information processing conducted by a process represented as a…

信息论 · 计算机科学 2018-08-01 Richard E. Spinney , Joseph T. Lizier

The paper deals with non-linear Poisson neuron network models with bounded memory dynamics, that can include both Hebbian learning mechanisms and refractory periods. The state of a network is described by the times elapsed since its neurons…

概率论 · 数学 2012-06-21 Konstantin Borovkov , Geoffrey Decrouez , Matthieu Gilson

The dynamics of a wide range of real systems, from email patterns to earthquakes, display a bursty, intermittent nature, characterized by short timeframes of intensive activity followed by long times of no or reduced activity. The…

数据分析、统计与概率 · 物理学 2007-05-23 Kwang-Il Goh , Albert-Laszlo Barabasi

Under normal operations, memristive devices undergo variability in time and space and have internal dynamics. Interplay of memory and stochastic signal processing in memristive devices makes them candidates for performing bio-inspired tasks…

新兴技术 · 计算机科学 2024-08-01 P. F. Gora , Ewa Gudowska-Nowak

Dense Associative Memory networks (DenseAMs) unify several popular paradigms in Artificial Intelligence (AI), such as Hopfield Networks, transformers, and diffusion models, while casting their computational properties into the language of…

统计力学 · 物理学 2026-04-07 Spencer Rooke , Dmitry Krotov , Vijay Balasubramanian , David Wolpert

Proximity networks are time-varying graphs representing the closeness among humans moving in a physical space. Their properties have been extensively studied in the past decade as they critically affect the behavior of spreading phenomena…

物理与社会 · 物理学 2019-11-28 Fragkiskos Papadopoulos , Marco Antonio Rodríguez Flores

The tunable mechanical response of knitted fabrics underpins applications ranging from soft robotics and artificial muscles to morphing electromagnetic field sensors. Elasticity in fabrics emerges from the bending of yarn in the knitted…

We show that a reversible pumping mechanism operating between two states of a kinetic network can give rise to Poisson transitions between these two states. An external observer, for whom the pumping mechanism is not accessible, will…

统计力学 · 物理学 2015-05-06 Massimiliano Esposito , Juan MR Parrondo

The dynamical mechanism underlying the processes of anesthesia-induced loss of consciousness and recovery is key to gaining insights into the working of the nervous system. Previous experiments revealed an asymmetry between neural signals…

神经元与认知 · 定量生物学 2020-04-10 Chun-Wang Su , Liang Zheng , You-Jun Li , Hai-Jun Zhou , Jue Wang , Zi-Gang Huang , Ying-Cheng Lai