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Spatial connectivity is an important consideration when modelling infectious disease data across a geographical region. Connectivity can arise for many reasons, including shared characteristics between regions, and human or vector movement.…

统计方法学 · 统计学 2022-06-06 Sophie A Lee , Theodoros Economou , Rachel Lowe

The increasing number of protein-based metamaterials demands reliable and efficient theoretical and computational methods to study the physicochemical properties they may display. In this regard, we develop a simulation strategy based on…

软凝聚态物质 · 物理学 2020-06-23 J. A. Campos Gonzalez Angulo , G. Wiesehan , R. F. Ribeiro , J. Yuen-Zhou

Many recent efforts in computational modeling of macro-scale brain dynamics have begun to take a data-driven approach by incorporating structural and/or functional information derived from subject data. Here, we discuss recent work using…

神经元与认知 · 定量生物学 2018-11-15 Kanika Bansal , Johan Nakuci , Sarah Feldt Muldoon

Longitudinal magnetic resonance imaging data is used to model trajectories of change in brain regions of interest to identify areas susceptible to atrophy in those with neurodegenerative conditions like Alzheimer's disease. Most methods for…

应用统计 · 统计学 2024-07-25 Robert Zielinski , Kun Meng , Ani Eloyan

There is an increasing need in solving high-dimensional optimization problems under non-deterministic environment. The simultaneous perturbation stochastic approximation (SPSA) algorithm has recently attracted considerable attention for…

最优化与控制 · 数学 2020-12-15 Chen Wang

There has been a growing interest in the use of Deep Neural Networks (DNNs) to solve Partial Differential Equations (PDEs). Despite the promise that such approaches hold, there are various aspects where they could be improved. Two such…

机器学习 · 计算机科学 2022-12-26 Amuthan A. Ramabathiran , Prabhu Ramachandran

Multidimensional scaling visualizes dissimilarities among objects and reduces data dimensionality. While many methods address symmetric proximity data, asymmetric and especially three-way proximity data (capturing relationships across…

统计方法学 · 统计学 2025-11-21 Aleix Alcacer , Rafael Benitez , Vicente J. Bolos , Irene Epifanio

Dimension reduction techniques have long been an important topic in statistics, and active subspaces (AS) have received much attention this past decade in the computer experiments literature. The most common approach towards estimating the…

统计方法学 · 统计学 2024-07-23 Kellin N. Rumsey , Devin Francom , Scott Vander Wiel

We present PSEUDo, an adaptive feature learning technique for exploring visual patterns in multi-track sequential data. Our approach is designed with the primary focus to overcome the uneconomic retraining requirements and inflexible…

机器学习 · 计算机科学 2021-05-11 Yuncong Yu , Dylan Kruyff , Tim Becker , Michael Behrisch

Splines are useful building blocks when constructing priors on nonparametric models indexed by functions. Recently it has been established in the literature that hierarchical priors based on splines with a random number of equally spaced…

统计理论 · 数学 2013-03-15 Eduard Belitser , Paulo Serra

Traditional neuron models use analog values for information representation and computation, while all-or-nothing spikes are employed in the spiking ones. With a more brain-like processing paradigm, spiking neurons are more promising for…

神经与进化计算 · 计算机科学 2021-02-05 Qiang Yu , Shiming Song , Chenxiang Ma , Linqiang Pan , Kay Chen Tan

Normal multi-scale transform [4] is a nonlinear multi-scale transform for representing geometric objects that has been recently investigated [1, 7, 10]. The restrictive role of the exact order of polynomial reproduction $P_e$ of the…

数值分析 · 数学 2013-11-19 Stanislav Harizanov

Cortical slow oscillations are an emergent property of the cortical network, a hallmark of low complexity brain states like sleep, and represent a default activity pattern. Here, we present a methodological approach for quantifying the…

Regression splines are smooth, flexible, and parsimonious nonparametric function estimators. They are known to be sensitive to knot number and placement, but if assumptions such as monotonicity or convexity may be imposed on the regression…

应用统计 · 统计学 2008-11-12 Mary C. Meyer

In the current era of big data, researchers routinely collect and analyze data of super-large sample sizes. Data-oriented statistical methods have been developed to extract information from super-large data. Smoothing spline ANOVA (SSANOVA)…

统计计算 · 统计学 2016-02-18 Nathaniel E. Helwig , Ping Ma

Developmental plasticity plays a prominent role in shaping the brain's structure during ongoing learning in response to dynamically changing environments. However, the existing network compression methods for deep artificial neural networks…

神经与进化计算 · 计算机科学 2024-10-29 Bing Han , Feifei Zhao , Yi Zeng , Guobin Shen

Physics-informed neural networks (PINNs) and their variants have recently emerged as alternatives to traditional partial differential equation (PDE) solvers, but little literature has focused on devising accurate numerical integration…

数值分析 · 数学 2024-01-03 Alexandre Magueresse , Santiago Badia

The last decade has seen the parallel emergence in computational neuroscience and machine learning of neural network structures which spread the input signal randomly to a higher dimensional space; perform a nonlinear activation; and then…

神经与进化计算 · 计算机科学 2013-06-11 Jonathan Tapson , Andre van Schaik

Characterising the representation of sensory stimuli in the brain is a fundamental scientific endeavor, which can illuminate principles of information coding. Most characterizations reduce the dimensionality of neural data by converting…

神经元与认知 · 定量生物学 2024-01-23 James B Isbister

Lower-dimensional subspaces that impact estimates of uncertainty are often described by Linear combinations of input variables, leading to active variables. This paper extends the derivative-based active subspace methods and…

数值分析 · 数学 2026-01-08 Matieyendou Lamboni , Sergei Kucherenko