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Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic…

Purpose: Transurethral ultrasound therapy is an investigational treatment modality which could potentially be used for the localized treatment of prostate cancer. One of the limiting factors of this therapy is prostatic calcifications.…

Background: Promising results for mammary carcinoma treatment with photodynamic therapy (PDT) presuppose a careful selection of irradiation light wavelength. Methods: 4T1 tumors implanted in NOD-SCID mice were treated with Metvix-PDT under…

In this work, we present a phase-field model for tumour growth, where a diffuse interface separates a tumour from the surrounding host tissue. In our model, we consider transport processes by an internal, non-solenoidal velocity field. We…

数值分析 · 数学 2024-06-21 Harald Garcke , Dennis Trautwein

The research on developing CNN-based fully-automated Brain-Tumor-Segmentation systems has been progressed rapidly. For the systems to be applicable in practice, a good The research on developing CNN-based fully-automated…

图像与视频处理 · 电气工程与系统科学 2022-05-04 Juncheng Tong , Chunyan Wang

Time domain identification is studied in this paper for parameters of a continuous-time multi-input multi-output descriptor system, with these parameters affecting system matrices through a linear fractional transformation. Sampling is…

多智能体系统 · 计算机科学 2025-06-17 Tong Zhou

Traditional dose selection for oncology registration trials typically employs a one- or two-step single maximum tolerated dose (MTD) approach. However, this approach may not be appropriate for molecularly targeted therapy that tends to have…

统计方法学 · 统计学 2023-09-28 Jason J. Z. Liao , Ekaterine Asatiani , Qingyang Liu , Kevin Hou

When to initiate treatment on patients is an important problem in many medical studies such as AIDS and cancer. In this article, we formulate the treatment initiation time problem for time-to-event data and propose an optimal individualized…

统计方法学 · 统计学 2021-09-30 Xin Chen , Rui Song , Jiajia Zhang , Swann Arp Adams , Liuquan Sun , Wenbin Lu

Lung cancer has the highest rate of cancer-caused deaths, and early-stage diagnosis could increase the survival rate. Lung nodules are common indicators of lung cancer, making their detection crucial. Various lung nodule detection models…

图像与视频处理 · 电气工程与系统科学 2025-03-04 Saeed Shakuri , Alireza Rezvanian

We present a finite-difference method for the topology optimization of permanent magnets that is based on the FFT accelerated computation of the stray-field. The presented method employs the density approach for topology optimization and…

Transcranial focused ultrasound stimulation (TUS) holds promise for non-invasive neural modulation in treating neurological disorders. Most clinically relevant targets are deep within the brain (near or at its geometric center), surrounded…

Molecular data from tumor profiles is high dimensional. Tumor profiles can be characterized by tens of thousands of gene expression features. Due to the size of the gene expression feature set machine learning methods are exposed to noisy…

机器学习 · 计算机科学 2020-07-14 Martin Palazzo , Pierre Beauseroy , Patricio Yankilevich

Response evaluation criteria in solid tumors (RECIST) is the standard measurement for tumor extent to evaluate treatment responses in cancer patients. As such, RECIST annotations must be accurate. However, RECIST annotations manually…

计算机视觉与模式识别 · 计算机科学 2018-06-26 Youbao Tang , Adam P. Harrison , Mohammadhadi Bagheri , Jing Xiao , Ronald M. Summers

Quantum embedding schemes have the potential to significantly reduce the computational cost of first principles calculations, whilst maintaining accuracy, particularly for calculations of electronic excitations in complex systems. In this…

材料科学 · 物理学 2022-03-10 Joseph C. A. Prentice

Treatment of cancer has rapidly evolved over time in quite dramatic ways, for example from chemotherapies, targeted therapies to immunotherapies and chimeric antigen receptor T-cells. Nonetheless, the basic design of early phase I trials in…

应用统计 · 统计学 2024-12-04 Lukas Andreas Widmer , Sebastian Weber , Yunnan Xu , Hans-Jochen Weber

Brain tumor is one of the leading causes of cancer-related death globally among children and adults. Precise classification of brain tumor grade (low-grade and high-grade glioma) at early stage plays a key role in successful prognosis and…

图像与视频处理 · 电气工程与系统科学 2020-11-19 Ruqian Hao , Khashayar Namdar , Lin Liu , Farzad Khalvati

It is proposed to treat cancer by the combination of a strong magnetic field with intense ultrasound. At the low electrical conductivity of tissue the magnetic field is not frozen into the tissue, and oscillates against the tissue which is…

综合物理 · 物理学 2009-06-04 Dr. Friedwardt Winterberg

Personalized medicine is the future of medical practice. In oncology, tumor heterogeneity assessment represents a pivotal step for effective treatment planning and prognosis prediction. Despite new procedures for DNA sequencing and…

The large bandwidth combined with ultra-massive multiple-input multiple-output (UM-MIMO) arrays enables terahertz (THz) systems to achieve terabits-per-second throughput. The THz systems are expected to operate in the near, intermediate, as…

信息论 · 计算机科学 2023-10-27 Simon Tarboush , Anum Ali , Tareq Y. Al-Naffouri