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Chemical reaction networks offer a natural nonlinear generalisation of linear Markov jump processes on a finite state-space. In this paper, we analyse the dynamical large deviations of such models, starting from their microscopic version,…

Stochastic diffusion is the noisy and uncertain process through which dynamics like epidemics, or agents like animal species, disperse over a larger area. Understanding these processes is becoming increasingly important as we attempt to…

We study fluctuations of small noise multiscale diffusions around their homogenized deterministic limit. We derive quantitative rates of convergence of the fluctuation processes to their Gaussian limits in the appropriate Wasserstein metric…

概率论 · 数学 2024-11-05 Solesne Bourguin , Konstantinos Spiliopoulos

Latent variable models are widely used in social and behavioural sciences, including education, psychology, and political science. With the increasing availability of large and complex datasets, high-dimensional latent variable models have…

统计计算 · 统计学 2025-12-09 Motonori Oka , Yunxiao Chen , Irini Moustaki

We describe a simple stochastic method, so-called Langevin approach, which enables one to extract evolution equations of stochastic variables from a set of measurements. Our method is parameter-free and it is based on the nonlinear Langevin…

数据分析、统计与概率 · 物理学 2015-02-19 Nico Reinke , André Fuchs , Wided Medjroubi , Pedro G. Lind , Matthias Wächter , Joachim Peinke

Nature presents multiple intriguing examples of processes which proceed at high precision and regularity. This remarkable stability is frequently counter to modelers' experience with the inherent stochasticity of chemical reactions in the…

分子网络 · 定量生物学 2015-12-31 Andreas Milias-Argeitis , Stefan Engblom , Pavol Bauer , Mustafa Khammash

We propose a stochastic model reduction strategy for deterministic and stochastic slow-fast systems with finite time-scale separation. The stochastic model reduction relaxes the assumption of infinite time-scale separation of classical…

统计力学 · 物理学 2018-04-26 Jeroen Wouters , Georg A. Gottwald

We introduce a general procedure for directly ascertaining how many independent stochastic sources exist in a complex system modeled through a set of coupled Langevin equations of arbitrary dimension. The procedure is based on the…

数据分析、统计与概率 · 物理学 2013-06-03 V. V. Vasconcelos , F. Raischel , M. Haase , J. Peinke , M. Wächter , P. G. Lind , D. Kleinhans

We present an ``equation-free'' multiscale approach to the simulation of unsteady diffusion in a random medium. The diffusivity of the medium is modeled as a random field with short correlation length, and the governing equations are cast…

数值分析 · 数学 2007-05-23 Dongbin Xiu , Ioannis Kevrekidis

Stochastic systems have a control-theoretic interpretation in which noise plays the role of control. In the weak-noise limit, relevant at low temperatures or in large populations, this leads to a precise mathematical mapping: the most…

分子网络 · 定量生物学 2025-09-03 Eric De Giuli

We apply a Gaussian variational approximation to model reduction in large biochemical networks of unary and binary reactions. We focus on a small subset of variables (subnetwork) of interest, e.g. because they are accessible experimentally,…

化学物理 · 物理学 2017-08-02 Barbara Bravi , Peter Sollich

In this short paper, we study the simulation of a large system of stochastic processes subject to a common driving noise and fast mean-reverting stochastic volatilities. This model may be used to describe the firm values of a large pool of…

数值分析 · 数学 2021-10-13 Andrei Cozma , Christoph Reisinger

We study the stochastic evolution of four species in cyclic competition in a well mixed environment. In systems composed of a finite number $N$ of particles these simple interaction rules result in a rich variety of extinction scenarios,…

统计力学 · 物理学 2012-07-09 C. H. Durney , S. O. Case , M. Pleimling , R. K. P. Zia

A large deviation principle is established for a two-scale stochastic system in which the slow component is a continuous process given by a small noise finite dimensional It\^{o} stochastic differential equation, and the fast component is a…

概率论 · 数学 2017-05-09 Amarjit Budhiraja , Paul Dupuis , Arnab Ganguly

We consider the modeling of the dynamics of the chemostat at its very source. The chemostat is classically represented as a system of ordinary differential equations. Our goal is to establish a stochastic model that is valid at the scale…

定量方法 · 定量生物学 2011-07-07 Fabien Campillo , Marc Joannides , Irène Larramendy

We investigate a stochastic version of a simple enzymatic reaction which follows the generic Michaelis-Menten kinetics. At sufficiently high concentrations of reacting species, the molecular fluctuations can be approximated as a realization…

种群与进化 · 定量生物学 2009-11-13 A. Fiasconaro , A. Ochab-Marcinek , B. Spagnolo , E. Gudowska-Nowak

We distinguish a mechanical representation of the world in terms of point masses with positions and momenta and the chemical representation of the world in terms of populations of different individuals, each with intrinsic stochasticity,…

统计力学 · 物理学 2019-05-07 Hong Qian

Normal human heart rate shows complex fluctuations in time, which is natural, since heart rate is controlled by a large number of different feedback control loops. These unpredictable fluctuations have been shown to display fractal…

医学物理 · 物理学 2009-11-07 Tom A. Kuusela , Tony Shepherd , Jarmo Hietarinta

We analyse four approaches to elimination of a fast variable, which are applicable to systems like passive Brownian particles: (i) moment formalism, (ii) corresponding cumulant formalism, (iii) Hermite function basis, (iv) formal…

For cellular biochemical reaction systems where the numbers of molecules is small, significant noise is associated with chemical reaction events. This molecular noise can give rise to behavior that is very different from the predictions of…

分子网络 · 定量生物学 2009-11-13 Matthew Scott , Terence Hwa , Brian Ingalls
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