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We analyze a class of general nonlinear epidemic models with age and space structure, including a nonlocal infection term depending on age and space. After establishing the well-posedness of the state partial differential equation, we…

最优化与控制 · 数学 2025-03-11 Behzad Azmi , Nicolas Schlosser

The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…

种群与进化 · 定量生物学 2021-05-18 G. Albi , L. Pareschi , M. Zanella

Understanding age-group dynamics of infectious diseases is a fundamental issue for both scientific study and policymaking. Age-structure epidemic models were developed in order to study and improve our understanding of these dynamics. By…

种群与进化 · 定量生物学 2019-11-22 Rami Yaari , Amit Huppert , Itai Dattner

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

最优化与控制 · 数学 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

In this survey we report some recent results in the mathematical modeling of epidemic phenomena through the use of kinetic equations. We initially consider models of interaction between agents in which social characteristics play a key role…

This paper combines a canonical epidemiology model of disease dynamics with government policy of lockdown and testing, and agents' decision to social distance in order to avoid getting infected. The model is calibrated with data on deaths…

综合经济学 · 经济学 2022-02-10 Shomak Chakrabarti , Ilia Krasikov , Rohit Lamba

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

应用统计 · 统计学 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

This paper proposes a feedback design that effectively copes with uncertainties for reliable epidemic monitoring and control. There are several optimization-based methods to estimate the parameters of an epidemic model by utilizing past…

最优化与控制 · 数学 2023-04-06 Muhammad Umar B. Niazi , Philip E. Paré , Karl H. Johansson

A new age-structured diffusive model for the mathematical modelling of epidemics is suggested. The model can be considered as a generalization of two models suggested earlier for the same purposes. The Lie symmetry classification of the…

种群与进化 · 定量生物学 2025-07-31 Roman Cherniha , Vasyl' Davydovych

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

种群与进化 · 定量生物学 2020-05-04 Andrew Lesniewski

Age structure is incorporated in many types of epidemic model. Often it is convenient to assume that such models converge to early asymptotic behaviour quickly, before the susceptible population has been appreciably depleted. We make use of…

种群与进化 · 定量生物学 2013-03-19 Christopher A. Rhodes , Thomas House

In this article, we consider the infinite dimensional linear control system describing the Population Models Structured by Age, Size, and Spatial Position. The control is localized in the space variable as well as with respect to the age…

最优化与控制 · 数学 2022-09-12 Yacouba Simpore , Umberto Biccari

We review the optimal control of systems modeling the dynamics of tuberculosis. Time dependent control functions are introduced in the mathematical models, representing strategies for the improvement of the treatment and cure of active…

最优化与控制 · 数学 2015-08-18 Cristiana J. Silva , Delfim F. M. Torres

In this manuscript we consider an age structured epidemic system modelling the dynamics of transmission of immunizing disease like Hepatitis B virus. Our model takes into account age as well as two classes of infected individuals (chronic…

偏微分方程分析 · 数学 2016-05-17 Yannick Tchaptchie Kouakep

To mitigate the impact of the pandemic, several measures include lockdowns, rapid vaccination programs, school closures, and economic stimulus. These interventions can have positive or unintended negative consequences. Current research to…

机器学习 · 计算机科学 2025-08-11 Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

We present and compare two different optimal control approaches applied to SEIR models in epidemiology, which allow us to obtain some policies for controlling the spread of an epidemic. The first approach uses Dynamic Programming to…

最优化与控制 · 数学 2024-05-06 Simone Cacace , Alessio Oliviero

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

动力系统 · 数学 2021-11-18 Lorenzo Zino , Ming Cao

We study several aspects of the dynamic programming approach to optimal control of abstract evolution equations, including a class of semilinear partial differential equations. We introduce and prove a verification theorem which provides a…

最优化与控制 · 数学 2007-06-12 G. Fabbri , F. Gozzi , A. Swiech

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

统计方法学 · 统计学 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert

This chapter reviews some aspects of the theory of age-structured models of populations with finite maximum age. We formulate both the renewal equation for the birth rate and the partial differential equation for the age density, and show…

种群与进化 · 定量生物学 2025-10-21 Odo Diekmann , Francesca Scarabel
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