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Thyroid cancer is said to be the second most common type of cancer in female individuals and the third in males by 2030, according to projections. In general, detecting cancer in its early stages improves the chance of survival of the…

计算机视觉与模式识别 · 计算机科学 2026-05-29 J. R. González , É. O. Rodrigues , C. P. Damião , C. A. P. Fontes , A. C. Silva , A. C. Paiva , H. Li , C. Du , A. Conci

Tuberculosis poses a global health risk and Brazil is among the top twenty countries by absolute mortality. However, this epidemiological burden is masked by under-reporting, which impairs planning for effective intervention. We present a…

应用统计 · 统计学 2019-03-12 Oliver Stoner , Theo Economou , Gabriela Drummond

The automatic identification of cough segments in audio through the determination of start and end points is pivotal to building scalable screening tools in health technologies for pulmonary related diseases. We propose the application of…

音频与语音处理 · 电气工程与系统科学 2026-03-13 Joshua Jansen van Vüren , Devendra Singh Parihar , Daphne Naidoo , Kimsey Zajac , Willy Ssengooba , Grant Theron , Thomas Niesler

Chronic diseases and cancer account for over 75 percent of healthcare costs in the US. Increased prevention services and improved primary care are thought to decrease costs. Current models for detecting changes in the health of populations…

种群与进化 · 定量生物学 2013-07-15 Jacob Kuriyan , Nathaniel Cobb

Skin conditions are a global health concern, ranking the fourth highest cause of nonfatal disease burden when measured as years lost due to disability. As diagnosing, or classifying, skin diseases can help determine effective treatment,…

计算机视觉与模式识别 · 计算机科学 2019-06-05 Jeremy Kawahara , Ghassan Hamarneh

Tuberculosis (TB) remains a leading global infectious disease, causing approximately 1.3 million deaths and 10.6 million new infections annually. Classical compartmental ODE models are the standard epidemiological tool for TB, yet their…

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

机器学习 · 计算机科学 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

统计方法学 · 统计学 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The progression and severity of MS varies by individual, but it is generally a disabling disease. Although medications have been developed to…

应用统计 · 统计学 2013-03-06 Joyce C. Ho , Joydeep Ghosh , KP Unnikrishnan

Major advances in public health have resulted from disease prevention. However, prevention of a new infectious disease by vaccination or pharmaceuticals is made difficult by the slow process of vaccine and drug development. We propose an…

种群与进化 · 定量生物学 2021-04-15 Jussi Taipale , Ioannis Kontoyiannis , Sten Linnarsson

Antimicrobial resistance is becoming a major threat to public health throughout the world. Researchers are attempting to contrast it by developing both new antibiotics and patient-specific treatments. In the second case, whole-genome…

应用统计 · 统计学 2023-07-25 Clara Grazian

Bovine tuberculosis (TB) poses a serious threat for agricultural industry in several countries, it involves potential interactions between wildlife and cattle and creates societal problems in terms of human-wildlife conflict. This study…

定量方法 · 定量生物学 2016-09-29 Aristides Moustakas , Matthew R Evans

Despite the rapid growth of the home care industry, research on the scheduling and routing of home care visits in the presence of uncertainty is still limited. This paper investigates a dynamic version of this problem in which the number of…

最优化与控制 · 数学 2024-03-19 Danial Khorasanian , Jonathan Patrick , Antoine Sauré

We consider a recent coinfection model for Tuberculosis (TB), Human Immunodeficiency Virus (HIV) infection and Acquired Immunodeficiency Syndrome (AIDS) proposed in [Discrete Contin. Dyn. Syst. 35 (2015), no. 9, 4639--4663]. We introduce…

最优化与控制 · 数学 2018-05-22 Roman Denysiuk , Cristiana J. Silva , Delfim F. M. Torres

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

计算机视觉与模式识别 · 计算机科学 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

Repeated decision-making problems under uncertainty may arise in the health policy context, such as infectious disease control for COVID-19 and other epidemics. These problems may sometimes be effectively solved using Markov decision…

最优化与控制 · 数学 2024-11-28 Suyanpeng Zhang , Sze-chuan Suen

In precision medicine, Dynamic Treatment Regimes (DTRs) are treatment protocols that adapt over time in response to a patient's observed characteristics. A DTR is a set of decision functions that takes an individual patient's information as…

统计方法学 · 统计学 2022-03-17 Cong Jiang , Michael Wallace , Mary Thompson

A common approach to medical image analysis on volumetric data uses deep 2D convolutional neural networks (CNNs). This is largely attributed to the challenges imposed by the nature of the 3D data: variable volume size, GPU exhaustion during…

图像与视频处理 · 电气工程与系统科学 2020-07-28 Hasib Zunair , Aimon Rahman , Nabeel Mohammed , Joseph Paul Cohen

Recently, a long-term model of HIV infection dynamics was developed to describe the entire time course of the disease. It consists of a large system of ODEs with many parameters, and is expensive to simulate. In the current paper, this…

种群与进化 · 定量生物学 2016-04-20 Tyson Loudon , Stephen Pankavich

Testing symptomatic individuals for a disease can deliver treatment resources, if tests' results turn positive, which speeds up their treatment and might also decrease individuals' contacts to other ones. An imperfect test, however, might…

种群与进化 · 定量生物学 2015-06-25 Daniel A. M. Villela