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An important feature of linear mixed models and generalized linear mixed models is that the conditional mean of the response given the random effects, after transformed by a link function, is linearly related to the fixed covariate effects…

应用统计 · 统计学 2008-12-29 Mingyan Huang , Daowen Zhang

In the last decades, it has been discussed the use of epidemiological prevalence ratio (PR) rather than odds ratio as a measure of association to be estimated in cross-sectional studies. The main difficulties in use of statistical models…

When some treatments are ordered according to the categories of an ordinal categorical variable (e.g., extent of side effects) in a monotone order, one might be interested in knowing wether the treatments are equally effective or not. One…

统计方法学 · 统计学 2014-02-24 Nirian Martín , Raquel Mata , Leandro Pardo

With advancement of medicine, alternative exposures or interventions are emerging with respect to a common outcome, and there are needs to formally test the difference in the associations of multiple exposures. We propose a duplication…

统计方法学 · 统计学 2024-12-04 Rikuta Hamaya , Peilu Wang , Lin Ge , Edward L. Giovannucci , Molin Wang

A formal likelihood ratio hypothesis test for the validity of a parametric regression function is proposed, using a large-dimensional, nonparametric double cone alternative. For example, the test against a constant function uses the…

统计方法学 · 统计学 2014-06-30 Bodhisattva Sen , Mary Meyer

There is growing interest in a hybrid control design in which a randomized controlled trial is augmented with an external control arm from a previous trial or real world data. Existing methods for analyzing hybrid control studies include…

统计方法学 · 统计学 2025-01-30 Zhiwei Zhang , Jialuo Liu , Wei Liu

The random coefficients model is an extension of the linear regression model that allows for unobserved heterogeneity in the population by modeling the regression coefficients as random variables. Given data from this model, the statistical…

统计方法学 · 统计学 2018-03-15 Fabian Dunker , Konstantin Eckle , Katharina Proksch , Johannes Schmidt-Hieber

This paper develops inference methods for ratios of deterministic trend slopes in systems of pairs of time series. Hypotheses based on linear cross-equation restrictions are considered with particular interest in tests that trend ratios are…

计量经济学 · 经济学 2026-03-02 Timothy J. Vogelsang

For some variants of regression models, including partial, measurement error or error-in-variables, latent effects, semi-parametric and otherwise corrupted linear models, the classical parametric tests generally do not perform well. Various…

统计理论 · 数学 2015-03-25 Pranab K. Sen , Jana Jureckova , Jan Picek

Clustered observations are ubiquitous in controlled and observational studies and arise naturally in multi-centre trials or longitudinal surveys. We present a novel model for the analysis of clustered observations where the marginal…

统计方法学 · 统计学 2022-11-03 Luisa Barbanti , Torsten Hothorn

Measurements are generally collected as unilateral or bilateral data in clinical trials or observational studies. For example, in ophthalmologic studies, statistical tests are often based on one or two eyes of an individual. For bilateral…

统计方法学 · 统计学 2020-10-08 Chang-Xing Ma , Kejia Wang

In current applied research the most-used route to an analysis of composition is through log-ratios -- that is, contrasts among log-transformed measurements. Here we argue instead for a more direct approach, using a statistical model for…

统计方法学 · 统计学 2023-12-19 David Firth , Fiona Sammut

Inference of instrumental variable regression models with many weak instruments attracts many attentions recently. To extend the classical Anderson-Rubin test to high-dimensional setting, many procedures adopt ridge-regularization. However,…

统计方法学 · 统计学 2025-04-30 Jiarong Ding , Xu Guo , Yanmei Shi , Yuxin Wang

Generalized linear models, such as logistic regression, are widely used to model the association between a treatment and a binary outcome as a function of baseline covariates. However, the coefficients of a logistic regression model…

统计方法学 · 统计学 2022-01-04 Jiaqi Yin , Sonia Markes , Thomas S. Richardson , Linbo Wang

Motivated by genome-wide association studies, we consider a standard linear model with one additional random effect in situations where many predictors have been collected on the same subjects and each predictor is analyzed separately.…

应用统计 · 统计学 2013-04-24 Matti Pirinen , Peter Donnelly , Chris C. A. Spencer

We extend the scope of risk measures for which backtesting models are available by proposing a multinomial backtesting method for general distortion risk measures. The method relies on a stratification and randomization of risk levels. We…

风险管理 · 定量金融 2024-08-02 Sören Bettels , Sojung Kim , Stefan Weber

This paper proposes a new feature screening method for the multi-response ultrahigh dimensional linear model by empirical likelihood. Through a multivariate moment condition, the empirical likelihood induced ranking statistics can exploit…

统计方法学 · 统计学 2022-06-07 Jun Lu , Qinqin Hu , Lu Lin

Paired comparison models, such as Bradley-Terry and Thurstone-Mosteller, are commonly used to estimate relative strengths of pairwise compared items in tournament-style data. We discuss estimation of paired comparison models with a ridge…

统计方法学 · 统计学 2024-10-03 Cristiano Varin , David Firth

Some large scale inference problems are considered based on using the relative belief ratio as a measure of statistical evidence. This approach is applied to the multiple testing problem. A particular application of this is concerned with…

统计理论 · 数学 2016-09-22 Michael Evans , Jabed Tomal

Covariate imbalance between treatment groups makes it difficult to compare cumulative incidence curves in competing risk analyses. In this paper we discuss different methods to estimate adjusted cumulative incidence curves including inverse…

统计方法学 · 统计学 2024-12-04 Patrick van Hage , Saskia le Cessie , Marissa C. van Maaren , Hein Putter , Nan van Geloven