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Super-resolution fluorescence microscopy is of great interest in life science studies for visualizing subcellular structures at the nanometer scale. Among various kinds of super-resolution approaches, image scanning microscopy (ISM) offers…

Electron matter interactions in electron microscopy produce both elastic and inelastic scattering, forming the basis for imaging and spectroscopy. However, the integration of electron energy loss spectroscopy (EELS) with 4D-STEM and…

材料科学 · 物理学 2025-07-22 Yu Lei , Peng Wang

Light-field microscopy represents a promising solution for microscopic volumetric imaging, thanks to its capability to encode information on multiple planes in a single acquisition. This is achieved through its peculiar simultaneous capture…

The multi-object spectrograph (MOS) has been the benchmark for the current generation of astronomical spectrographs, valued for its ability to acquire the spectra of hundreds of objects simultaneously. In the last two decades, the digital…

天体物理仪器与方法 · 物理学 2022-10-03 Shaojie Chen , Matthew C. H. Leung , Xuefeng Yao , Suresh Sivanandam , Isabelle Sanders , Rosalind Liang

We present an imaging technique that allows the recovery of the transparency profile of wavelength-scale objects with deep subwavelength resolution based on far-field intensity measurements. The approach, interscale mixing microscopy (IMM),…

光学 · 物理学 2017-03-21 Sandeep Inampudi , Nicholas Kuhta , Viktor A. Podolskiy

The possibility of spatially resolving the optical properties of atomically thin materials is especially appealing as they can be modulated at the micro- and nanoscale by reducing their thickness, changing the doping level or applying a…

介观与纳米尺度物理 · 物理学 2016-03-23 Andres Castellanos-Gomez , Jorge Quereda , Herko P. van der Meulen , Nicolás Agraït , Gabino Rubio-Bollinger

We design and characterize phase-modulated, ultra-compact, silicon-based axilens devices that combine efficient point focusing and grating selectivity within scalable 4-level phase mask configurations. The proposed designs are polarization…

光学 · 物理学 2020-03-20 Wesley A. Britton , Yuyao Chen , Fabrizio Sgrignuoli , Luca Dal Negro

We present a dual-wavelength external holographic microscopy module for quantitative phase imaging of 3D structures with extended thickness range. This is done by simultaneous acquisition of two off-axis interferograms, each of which at a…

光学 · 物理学 2019-04-10 Nir A. Turko , Natan T. Shaked

Ptychographic extreme ultraviolet (EUV) diffractive imaging has emerged as a promising candidate for the next-generation metrology solutions in the semiconductor industry, as it can image wafer samples in reflection geometry at the…

图像与视频处理 · 电气工程与系统科学 2023-11-28 Yifeng Shao , Sven Weerdenburg , Jacob Seifert , H. Paul Urbach , Allard P. Mosk , Wim Coene

Rapid and programmable shaping of light fields is central to modern microscopy, display technologies, optical communications and sensing, quantum engineering, and quantum information processing. Current wavefront shaping technologies face a…

量子物理 · 物理学 2026-01-15 Xin Wei , Zeyang Li , Abhishek V. Karve , Adam L. Shaw , David I. Schuster , Jonathan Simon

This paper proposes a non-computational method of counteracting the effect of image degradation introduced by the diffraction phenomenon in lensless microscopy. All the optical images (whether focused by lenses or not) are diffraction…

光学 · 物理学 2021-04-08 Sanjeev Kumar , Manjunatha Mahadevappa , Pranab Kumar Dutta

A full-field chromatic confocal microscopy using a multispectral sensor was developed for quasi-one-shot microscopic 3D surface measurement. An innovative optical configuration employs a digital micromirror device (DMD) and a multispectral…

In this work, we present and investigate the novel blind inverse problem of position-blind ptychography, i.e., ptychographic phase retrieval without any knowledge of scan positions, which then must be recovered jointly with the image. The…

图像与视频处理 · 电气工程与系统科学 2026-03-18 Simon Welker , Lorenz Kuger , Tim Roith , Berthy Feng , Martin Burger , Timo Gerkmann , Henry Chapman

We present a novel approach to achieve hyper spectral resolution, high sensitive detection, and high speed data acquisition Stimulated Raman Spectroscopy by employing amplified offset-phase controlled fs-pulse bursts. In this approach, the…

We present the first on-sky results of the micro-lens ring tip-tilt (MLR-TT) sensor. This sensor utilizes a 3D printed micro-lens ring feeding six multi-mode fibers to sense misaligned light, allowing centroid reconstruction. A tip-tilt…

Tip-enhanced nano-spectroscopy and -imaging, such as tip-enhanced photoluminescence (TEPL), tip-enhanced Raman spectroscopy (TERS), and others, have become indispensable from materials science to single molecule studies. However, the…

Fourier ptychographic (FP) microscope is a coherent imaging method that can synthesize an image with a higher bandwidth using multiple low-bandwidth images captured at different spatial frequency regions. The method's demand for multiple…

光学 · 物理学 2016-03-25 Jaebum Chung , Hangwen Lu , Xiaoze Ou , Haojiang Zhou , Changhuei Yang

Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip…

Label-free imaging of rapidly moving, sub-diffraction sized structures has important applications in both biology and material science, as it removes the limitations associated with fluorescence tagging. However, unlabeled nanoscale…

We introduce a conceptual framework for a lensless imaging system which employs an active metasurface as a high-frequency, continuously tunable amplitude and phase modulation aperture, coupled to a discrete single-pixel detector. Using an…

光学 · 物理学 2024-11-14 Julie Belleville , Prachi Thureja , Harry A. Atwater