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The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

图像与视频处理 · 电气工程与系统科学 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

Alzheimer`s disease (AD)-related global healthcare cost is estimated to be $1 trillion by 2050. Currently, there is no cure for this disease; however, clinical studies show that early diagnosis and intervention helps to extend the quality…

计算机与社会 · 计算机科学 2020-05-27 Ning Wang , Fan Luo , Vishal Peddagangireddy , K. P. Subbalakshmi , R. Chandramouli

Alzheimer's disease and related dementias (ADRD) affect one in five adults over 60, yet more than half of individuals with cognitive decline remain undiagnosed. Speech-based assessments show promise for early detection, as phonetic motor…

Alzheimers disease (AD) is a severe neurological brain disorder. It is not curable, but earlier detection can help improve symptoms in a great deal. The machine learning based approaches are popular and well motivated models for medical…

图像与视频处理 · 电气工程与系统科学 2024-05-17 Lilia Lazli

Automated speech analysis is a thriving approach to detect early markers of Alzheimer's disease (AD). Yet, recording conditions in most AD datasets are heterogeneous, with patients and controls often evaluated in different acoustic…

Recent progress has been made in detecting early stage dementia entirely through recordings of patient speech. Multimodal speech analysis methods were applied to the PROCESS challenge, which requires participants to use audio recordings of…

音频与语音处理 · 电气工程与系统科学 2025-02-14 Lei Chi , Arav Sharma , Ari Gebhardt , Joseph T. Colonel

We present two multimodal fusion-based deep learning models that consume ASR transcribed speech and acoustic data simultaneously to classify whether a speaker in a structured diagnostic task has Alzheimer's Disease and to what degree,…

计算与语言 · 计算机科学 2021-07-01 Morteza Rohanian , Julian Hough , Matthew Purver

Early diagnosis of Alzheimer's Disease (AD), particularly at the mild cognitive impairment stage, is essential for timely intervention. However, this process faces significant barriers, including reliance on subjective assessments and the…

计算机视觉与模式识别 · 计算机科学 2025-12-19 Changwei Wu , Yifei Chen , Yuxin Du , Jinying Zong , Jie Dong , Mingxuan Liu , Feiwei Qin , Yong Peng , Jin Fan , Changmiao Wang

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

图像与视频处理 · 电气工程与系统科学 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

Current work on speech-based dementia assessment focuses on either feature extraction to predict assessment scales, or on the automation of existing test procedures. Most research uses public data unquestioningly and rarely performs a…

音频与语音处理 · 电气工程与系统科学 2025-08-07 Franziska Braun , Christopher Witzl , Andreas Erzigkeit , Hartmut Lehfeld , Thomas Hillemacher , Tobias Bocklet , Korbinian Riedhammer

Deep learning (DL) techniques involving fine-tuning large numbers of model parameters have delivered impressive performance on the task of discriminating between language produced by cognitively healthy individuals, and those with…

计算与语言 · 计算机科学 2022-03-28 Changye Li , David Knopman , Weizhe Xu , Trevor Cohen , Serguei Pakhomov

Structural magnetic resonance imaging (MRI) studies have shown that Alzheimer's Disease (AD) induces both localised and widespread neural degenerative changes throughout the brain. However, the absence of segmentation that highlights brain…

图像与视频处理 · 电气工程与系统科学 2024-06-21 Chen Zheng

Automatically detecting Alzheimer's Disease (AD) from spontaneous speech plays an important role in its early diagnosis. Recent approaches highly rely on the Transformer architectures due to its efficiency in modelling long-range context…

声音 · 计算机科学 2024-05-08 Zhongren Dong , Zixing Zhang , Weixiang Xu , Jing Han , Jianjun Ou , Björn W. Schuller

Accurate diagnosis of Alzheimer's disease (AD) is both challenging and time consuming. With a systematic approach for early detection and diagnosis of AD, steps can be taken towards the treatment and prevention of the disease. This study…

机器学习 · 计算机科学 2022-12-12 Harshit Parmar , Eric Walden

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, structural brain changes, and genetic predispositions. This study leverages machine-learning and statistical techniques to investigate…

应用统计 · 统计学 2025-10-29 Riddhik Basu , Arkaprava Roy

Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…

机器学习 · 计算机科学 2023-02-17 Shrish Pellakur , Nelly Elsayed , Zag ElSayed , Murat Ozer

Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment…

计算机视觉与模式识别 · 计算机科学 2020-04-07 Ahsan Bin Tufail , Qiu-Na Zhang , Yong-Kui Ma

In this work we explore how language models can be employed to analyze language and discriminate between mentally impaired and healthy subjects through the perplexity metric. Perplexity was originally conceived as an information-theoretic…

计算与语言 · 计算机科学 2023-02-03 Davide Colla , Matteo Delsanto , Marco Agosto , Benedetto Vitiello , Daniele Paolo Radicioni

Deep transformer models have been used to detect linguistic anomalies in patient transcripts for early Alzheimer's disease (AD) screening. While pre-trained neural language models (LMs) fine-tuned on AD transcripts perform well, little…

计算与语言 · 计算机科学 2025-06-09 Zhecheng Sheng , Xiruo Ding , Brian Hur , Changye Li , Trevor Cohen , Serguei Pakhomov

Early detection of Alzheimer's Disease (AD) is greatly beneficial to AD patients, leading to early treatments that lessen symptoms and alleviating financial burden of health care. As one of the leading signs of AD, language capability…

计算与语言 · 计算机科学 2025-10-17 Yangyang Li