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相关论文: Group testing as a strategy for the epidemiologic …

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When testing for a disease such as COVID-19, the standard method is individual testing: we take a sample from each individual and test these samples separately. An alternative is pooled testing (or "group testing"), where samples are mixed…

应用统计 · 统计学 2021-12-14 Matthew Aldridge , David Ellis

COVID-19, a viral respiratory pandemic, has rapidly spread throughout the globe. Large scale and rapid testing of the population is required to contain the disease, but such testing is prohibitive in terms of resources, cost and time.…

种群与进化 · 定量生物学 2020-07-21 Abhishek Srivastava , Anurag Mishra , Trusha Jayant Parekh , Sampreeti Jena

The usual problem for group testing is this: For a given number of individuals and a given prevalence, how many tests T* are required to find every infected individual? In real life, however, the problem is usually different: For a given…

应用统计 · 统计学 2021-07-21 Matthew Aldridge

Background: Rapid testing for an infection is paramount during a pandemic to prevent continued viral spread and excess morbidity and mortality. This study aimed to determine whether alternative testing strategies based on sample pooling can…

种群与进化 · 定量生物学 2021-01-27 Timo de Wolff , Dirk Pflüger , Michael Rehme , Janin Heuer , Martin-Immanuel Bittner

We present a method for efficient estimation of the prevalence of infection in a population with high accuracy using only a small number of tests. The presented approach uses pool testing with a mix of pool sizes of various sizes. The test…

应用统计 · 统计学 2020-04-08 Itsik Bergel

COVID-19 has resulted in a global health crisis that may become even more acute over the upcoming months. One of the main reasons behind the current rapid growth of COVID-19 in the U.S. population is the limited availability of testing kits…

信息论 · 计算机科学 2020-04-13 Krishna R. Narayanan , Anoosheh Heidarzadeh , Ramanan Laxminarayan

The corona virus disease 2019 (COVID-19) caused by the novel corona virus has an exponential rate of infection. COVID-19 is particularly notorious as the onset of symptoms in infected patients are usually delayed and there exists a large…

统计方法学 · 统计学 2020-04-16 Lakshmi N. Theagarajan

A key requirement in containing contagious diseases, such as the Coronavirus disease 2019 (COVID-19) pandemic, is the ability to efficiently carry out mass diagnosis over large populations. Some of the leading testing procedures, such as…

定量方法 · 定量生物学 2022-08-31 Amit Solomon , Alejandro Cohen , Nir Shlezinger , Yonina C. Eldar , Muriel Médard

We consider a novel method to increase the reliability of COVID-19 virus or antibody tests by using specially designed pooled testings. Instead of testing nasal swab or blood samples from individual persons, we propose to test mixtures of…

定量方法 · 定量生物学 2020-07-30 Jirong Yi , Myung Cho , Xiaodong Wu , Weiyu Xu , Raghu Mudumbai

Fast testing can help mitigate the coronavirus disease 2019 (COVID-19) pandemic. Despite their accuracy for single sample analysis, infectious diseases diagnostic tools, like RT-PCR, require substantial resources to test large populations.…

定量方法 · 定量生物学 2020-04-08 Junan Zhu , Kristina Rivera , Dror Baron

As humanity struggles to contain the global Covid-19 infection, prophylactic actions are grandly slowed down by the shortage of testing kits. Governments have taken several measures to work around this shortage: the FDA has become more…

We develop a statistical model for the testing of disease prevalence in a population. The model assumes a binary test result, positive or negative, but allows for biases in sample selection and both type I (false positive) and type II…

应用统计 · 统计学 2021-12-28 Lucas Böttcher , Maria R. D'Orsogna , Tom Chou

Repeated asymptomatic screening for SARS-CoV-2 promises to control spread of the virus but would require too many resources to implement at scale. Group testing is promising for screening more people with fewer test resources: multiple…

种群与进化 · 定量生物学 2020-11-18 Yifan Lin , Yuxuan Ren , Jingyuan Wan , Massey Cashore , Jiayue Wan , Yujia Zhang , Peter Frazier , Enlu Zhou

Testing is recommended for all close contacts of confirmed COVID-19 patients. However, existing group testing methods are oblivious to the circumstances of contagion provided by contact tracing. Here, we build upon a well-known…

应用统计 · 统计学 2021-07-01 Stratis Tsirtsis , Abir De , Lars Lorch , Manuel Gomez-Rodriguez

The cataclysmic contagion based calamity -- Covid-19 has shown us a clear need for a comprehensive community based strategy that overcomes the sheer complexity of controlling it and the caveats of current methods. In this regard, as seen in…

物理与社会 · 物理学 2021-09-17 Surya Dheeshjith , Inavamsi Enaganti , Bud Mishra

Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…

应用统计 · 统计学 2021-07-13 Saskia Comess , Hannah Wang , Susan Holmes , Claire Donnat

Estimating the prevalence of a disease is necessary for evaluating and mitigating risks of its transmission within or between populations. Estimates that consider how prevalence changes with time provide more information about these risks…

应用统计 · 统计学 2021-11-12 Braden Scherting , Alison Peel , Raina Plowright , Andrew Hoegh

In comparison with individual testing, group testing (also known as pooled testing) is more efficient in reducing the number of tests and potentially leading to tremendous cost reduction. As indicated in the recent article posted on the US…

种群与进化 · 定量生物学 2021-06-16 Yi-Jheng Lin , Che-Hao Yu , Tzu-Hsuan Liu , Cheng-Shang Chang , Wen-Tsuen Chen

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

应用统计 · 统计学 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

We propose `Tapestry', a novel approach to pooled testing with application to COVID-19 testing with quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR) that can result in shorter testing time and conservation of reagents…

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