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Governments and public health authorities use seroprevalence studies to guide responses to the COVID-19 pandemic. Seroprevalence surveys estimate the proportion of individuals who have detectable SARS-CoV-2 antibodies. However, serologic…

应用统计 · 统计学 2022-11-11 Samuel P. Rosin , Bonnie E. Shook-Sa , Stephen R. Cole , Michael G. Hudgens

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

种群与进化 · 定量生物学 2019-11-28 Sang Woo Park , Benjamin M. Bolker

HIV transmission within serodiscordant couples remains a significant public health challenge, particularly in sub-Saharan Africa. Estimating the rate of such infection, alongside the rates of introduction of infection from outside the…

应用统计 · 统计学 2026-02-05 Irene García Muñoz , Ian Hall , Thomas House

Network scientists have proposed that infectious diseases involving person-to-person transmission may be effectively halted by targeting interventions at a minority of highly connected individuals. Can this strategy be effective in…

社会与信息网络 · 计算机科学 2020-11-16 Gianluca Manzo , Arnout van de Rijt

COVID-19 has shown a relatively low mortality rate in young healthy individuals, with the majority of this group being asymptomatic or having mild symptoms, while the severity of the disease among individuals with underlying health…

物理与社会 · 物理学 2020-06-22 Dario Ortega Anderez , Eiman Kanjo , Ganna Pogrebna , Shane Johnson , John Alan Hunt

The spreading of an infectious disease can trigger human behavior responses to the disease, which in turn plays a crucial role on the spreading of epidemic. In this study, to illustrate the impacts of the human behavioral responses, a new…

物理与社会 · 物理学 2015-09-30 Can Liu , Jia-Rong Xie , Han-Shuang Chen , Hai-Feng Zhang , Ming Tang

Despite the progress in medical data collection the actual burden of SARS-CoV-2 remains unknown due to under-ascertainment of cases. This was apparent in the acute phase of the pandemic and the use of reported deaths has been pointed out as…

应用统计 · 统计学 2023-07-13 Anastasia Chatzilena , Nikolaos Demiris , Konstantinos Kalogeropoulos

The global pandemic of the 2019-nCov requires the evaluation of policy interventions to mitigate future social and economic costs of quarantine measures worldwide. We propose an epidemiological model for forecasting and policy evaluation…

应用统计 · 统计学 2020-10-30 Philip Nadler , Shuo Wang , Rossella Arcucci , Xian Yang , Yike Guo

In multivariate pattern analysis of neuroimaging data, 'second-level' inference is often performed by entering classification accuracies into a $t$-test vs chance level across subjects. We argue that while the random-effects analysis…

神经元与认知 · 定量生物学 2016-08-11 Carsten Allefeld , Kai Görgen , John-Dylan Haynes

As COVID-19 is rapidly spreading across the globe, short-term modeling forecasts provide time-critical information for decisions on containment and mitigation strategies. A main challenge for short-term forecasts is the assessment of key…

In this paper we develop statistical methods for causal inference in epidemics. Our focus is in estimating the effect of social mobility on deaths in the Covid-19 pandemic. We propose a marginal structural model motivated by a modified…

统计方法学 · 统计学 2021-08-25 Matteo Bonvini , Edward Kennedy , Valerie Ventura , Larry Wasserman

Contact-tracing is an essential tool in order to mitigate the impact of pandemic such as the COVID-19. In order to achieve efficient and scalable contact-tracing in real time, digital devices can play an important role. While a lot of…

The generation interval is the time between the infection time of an infected person and the infection time of his or her infector. Probability density functions for generation intervals have been an important input for epidemic models and…

定量方法 · 定量生物学 2023-10-24 Eben Kenah , Marc Lipsitch , James M. Robins

The concept of the effective infection opportunity population (EIOP) was incorporated into the SIQR model, and it was assumed that this EIOP would change with the spread of infection, and this was named as the effective SIQR model. When…

种群与进化 · 定量生物学 2020-10-13 Hiroshi Isshiki , Masao Namiki

During 2020 and 2021, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission has been increasing amongst the world's population at an alarming rate. Reducing the spread of SARS-CoV-2 and other diseases that are spread in…

社会与信息网络 · 计算机科学 2022-03-22 Patrick Urrutia , David Wren , Chrysafis Vogiatzis , Ruriko Yoshida

At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…

最优化与控制 · 数学 2023-03-22 Chung-Han Hsieh

In this study, we propose a time-dependent Susceptible-Exposed-Infected-Recovered (SEIR) model for the analysis of the SARS-CoV-2 epidemic outbreak in three different countries, the United States of America, Italy and Iceland using public…

种群与进化 · 定量生物学 2021-11-08 P. Girardi , C. Gaetan

Stemming from the high profile publication of Nissen and Wolski (2007) and subsequent discussions with divergent views on how to handle observed zero-total-event studies, defined to be studies which observe zero events in both treatment and…

统计方法学 · 统计学 2023-10-23 Xiaolin Chen , Jerry Q Cheng , Lu Tian , Minge Xie

The recent COVID-19 pandemic has shown that when the reproduction number is high and there are no proper measurements in place, the number of infected people can increase dramatically in a short time, producing a phenomenon that many…

种群与进化 · 定量生物学 2022-09-20 Jonathan A. Chávez Casillas

Despite many studies on the transmission mechanism of the Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), it remains still challenging to efficiently reduce mortality. In this work, we apply a two-population…

物理与社会 · 物理学 2021-09-14 Long Ma , Maksim Kitsak , Piet Van Mieghem