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We propose two SIR models which incorporate sociological behavior of groups of individuals. It is these differences in behaviors which impose different infection rates on the individual susceptible populations, rather than biological…

动力系统 · 数学 2022-07-26 Robert F. Allen , Katherine Heller , Matthew A. Pons

In this paper we introduce a novel method to conduct inference with models defined through a continuous-time Markov process, and we apply these results to a classical stochastic SIR model as a case study. Using the inverse-size expansion of…

应用统计 · 统计学 2011-11-10 Marcos A. Capistrán , J. Andrés Christen , Jorge X. Velasco-Hernández

The relative case fatality rates (CFRs) between groups and countries are key measures of relative risk that guide policy decisions regarding scarce medical resource allocation during the ongoing COVID-19 pandemic. In the middle of an active…

定量方法 · 定量生物学 2022-12-08 Anastasios Nikolas Angelopoulos , Reese Pathak , Rohit Varma , Michael I. Jordan

A stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a social network is analysed. The underlying social network is described by an Erd\H{o}s-R\'{e}nyi random graph but, during the course of the epidemic,…

概率论 · 数学 2020-08-17 Frank Ball , Tom Britton

In this expository paper, we consider the problem of causal inference and efficient estimation for the counterfactual survivor function. This problem has previously been considered in the literature in several papers, each relying on the…

统计方法学 · 统计学 2025-10-02 Benjamin R. Baer , Ashkan Ertefaie , Robert L. Strawderman

Epidemics are inherently stochastic, and stochastic models provide an appropriate way to describe and analyse such phenomena. Given temporal incidence data consisting of, for example, the number of new infections or removals in a given time…

统计方法学 · 统计学 2024-05-24 Sam A. Whitaker , Andrew Golightly , Colin S. Gillespie , Theodore Kypraios

The COVID-19 pandemic has caused major disturbance to human life. An important reason behind the widespread social anxiety is the huge uncertainty about the pandemic. A fundamental uncertainty is how many or what percentage of people have…

种群与进化 · 定量生物学 2021-03-04 Donghui Yan , Ying Xu , Pei Wang

The number of new infections per day is a key quantity for effective epidemic management. It can be estimated relatively directly by testing of random population samples. Without such direct epidemiological measurement, other approaches are…

应用统计 · 统计学 2021-06-18 Simon N. Wood

Countries officially record the number of COVID-19 cases based on medical tests of a subset of the population with unknown participation bias. For prevalence estimation, the official information is typically discarded and, instead, small…

统计方法学 · 统计学 2020-12-25 Stéphane Guerrier , Christoph Kuzmics , Maria-Pia Victoria-Feser

Large-scale datasets are increasingly being used to inform decision making. While this effort aims to ground policy in real-world evidence, challenges have arisen as selection bias and other forms of distribution shifts often plague…

统计方法学 · 统计学 2023-11-07 Santiago Cortes-Gomez , Mateo Dulce , Carlos Patino , Bryan Wilder

An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc.…

应用统计 · 统计学 2026-02-10 Donghui Yan , Aiyou Chen , Buqing Yang

Recent work has focused attention on statistical inference for the population distribution of the number of sexual partners based on survey data. The characteristics of these distributions are of interest as components of mathematical…

无序系统与神经网络 · 物理学 2007-05-23 Mark S. Handcock , James Holland Jones , Martina Morris

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e. the number of…

种群与进化 · 定量生物学 2019-12-05 F. Di Lauro , J. -C. Croix , M. Dashti , L. Berthouze , I. Z. Kiss

The discovery of SARS-CoV-2, the responsible virus for the Covid-19 epidemic, has sparked a global health concern with many countries affected. Developing models that can interpret the epidemic and give common trend parameters are useful…

种群与进化 · 定量生物学 2021-09-21 Milad Radiom , Jean-Franccois Berret

Parameters of sub-populations can be more relevant than super-population ones. For example, a healthcare provider may be interested in the effect of a treatment plan for a specific subset of their patients; policymakers may be concerned…

统计方法学 · 统计学 2023-03-22 Ying Jin , Dominik Rothenhäusler

A stochastic epidemic model accounting for the effect of contact-tracing on the spread of an infectious disease is studied. Precisely, individuals identified as infected may contribute to detecting other infectious individuals by providing…

概率论 · 数学 2009-03-28 Stéphan Clémençon , Viet Chi Tran , Hector De Arazoza

We consider the spread of a Susceptible-Infected-Recovered (SIR) disease through finite populations and derive an expression for the final size distribution. Our derivation allows arbitrary distributions of the number of transmissions…

种群与进化 · 定量生物学 2019-07-12 Joel C Miller

Globally the SARS-CoV-2 coronavirus has infected more than 59 million people and killed more than 1.39 million. Designing and monitoring interventions to slow and stop the spread of the virus require knowledge of how many people have been…

In this paper, we estimate the seroprevalence against COVID-19 by country and derive the seroprevalence over the world. To estimate seroprevalence, we use serological surveys (also called the serosurveys) conducted within each country. When…

应用统计 · 统计学 2022-02-01 Kwangmin Lee , Seongmin Kim , Seongil Jo , Jaeyong Lee

This primer describes the statistical uncertainty in mechanistic models and provides R code to quantify it. We begin with an overview of mechanistic models for infectious disease, and then describe the sources of statistical uncertainty in…

统计方法学 · 统计学 2021-01-25 Lucy D'Agostino McGowan , Kyra H. Grantz , Eleanor Murray