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The effective control of the COVID-19 pandemic is one the most challenging issues of nowadays. The design of optimal control policies is perplexed from a variety of social, political, economical and epidemiological factors. Here, based on…

动力系统 · 数学 2023-03-16 Antonis Armaou , Bryce Katch , Lucia Russo , Constantinos Siettos

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

种群与进化 · 定量生物学 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

物理与社会 · 物理学 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

After the introduction of drastic containment measures aimed at stopping the epidemic contagion from SARS-CoV2, many governments have adopted a strategy based on a periodic relaxation of such measures in the face of a severe economic crisis…

种群与进化 · 定量生物学 2021-06-10 Giacomo Albi , Lorenzo Pareschi , Mattia Zanella

The spreading dynamics of infectious diseases is influenced by individual behaviours, which are in turn affected by the level of awareness about the epidemic. Modelling the co-evolution of disease transmission and behavioural changes within…

物理与社会 · 物理学 2026-02-27 Daniele Proverbio , Riccardo Tessarin , Giulia Giordano

The importance of spatial networks in the spread of an epidemic is an essential aspect in modeling the dynamics of an infectious disease. Additionally, any realistic data-driven model must take into account the large uncertainty in the…

种群与进化 · 定量生物学 2022-01-17 Giulia Bertaglia , Lorenzo Pareschi

The COVID-19 pandemic has forced policy makers to decree urgent confinements to stop a rapid and massive contagion. However, after that stage, societies are being forced to find an equilibrium between the need to reduce contagion rates and…

In this survey we report some recent results in the mathematical modeling of epidemic phenomena through the use of kinetic equations. We initially consider models of interaction between agents in which social characteristics play a key role…

Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…

种群与进化 · 定量生物学 2024-05-13 Alberto d'Onofrio , Mimmo Iannelli , Piero Manfredi , Gabriela Marinoschi

Understanding how to effectively control an epidemic spreading on a network is a problem of paramount importance for the scientific community. The ongoing COVID-19 pandemic has highlighted the need for policies that mitigate the spread,…

种群与进化 · 定量生物学 2021-09-14 Carlo Cenedese , Lorenzo Zino , Michele Cucuzzella , Ming Cao

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

种群与进化 · 定量生物学 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

Compartmental models have long served as important tools in mathematical epidemiology, with their usefulness highlighted by the recent COVID-19 pandemic. However, most of the classical models fail to account for certain features of this…

动力系统 · 数学 2023-08-21 Monique Chyba , Taylor Klotz , Yuriy Mileyko , Corey Shanbrom

Deterministic compartmental models have been used extensively in modeling epidemic propagation. These models are required to fit available data and numerical procedures are often implemented to this end. But not every model architecture is…

种群与进化 · 定量生物学 2021-11-23 Gabriel Turinici

The recent coronavirus disease (COVID-19) outbreak has dramatically increased the public awareness and appreciation of the utility of dynamic models. At the same time, the dissemination of contradictory model predictions has highlighted…

种群与进化 · 定量生物学 2020-06-26 Gemma Massonis , Julio R. Banga , Alejandro F. Villaverde

The COVID-19 outbreak has stimulated the interest in the proposal of novel epidemiological models to predict the course of the epidemic so as to help planning effective control strategies. In particular, in order to properly interpret the…

机器学习 · 计算机科学 2021-01-29 Andrea Zugarini , Enrico Meloni , Alessandro Betti , Andrea Panizza , Marco Corneli , Marco Gori

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

种群与进化 · 定量生物学 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

It is recognized that social heterogeneities in terms of the contact distribution have a strong influence on the spread of infectious diseases. Nevertheless, few data are available on the group composition of social contacts, and their…

最优化与控制 · 数学 2023-06-09 Jonathan Franceschi , Andrea Medaglia , Mattia Zanella

In the absence of drugs and vaccines, policymakers use non-pharmaceutical interventions such as social distancing to decrease rates of disease-causing contact, with the aim of reducing or delaying the epidemic peak. These measures carry…

种群与进化 · 定量生物学 2021-04-22 Dylan H. Morris , Fernando W. Rossine , Joshua B. Plotkin , Simon A. Levin

After the COVID-19 pandemic, we saw an increase in demand for epidemiological mathematical models. The goal of this work is to study the optimal control for an age-structured model as a strategy of quarantine of infected people, which is…

最优化与控制 · 数学 2024-11-04 Nelson L. Santos Junior , João A. M. Gondim

A novel parametric regression model is proposed to fit incidence data typically collected during epidemics. The proposal is motivated by real-time monitoring and short-term forecasting of the main epidemiological indicators within the first…

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