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Observational longitudinal studies are a common means to study treatment efficacy and safety in chronic mental illness. In many such studies, treatment changes may be initiated by either the patient or by their clinician and can thus vary…

统计方法学 · 统计学 2020-06-12 Zekun Xu , Eric Laber , Ana-Maria Staicu , Emanuel Severus

Characterizing the dynamic interactive patterns of complex systems helps gain in-depth understanding of how components interrelate with each other while performing certain functions as a whole. In this study, we present a novel multimodal…

机器学习 · 计算机科学 2019-01-07 Miaolin Fan , Chun-An Chou , Sheng-Che Yen , Yingzi Lin

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

人工智能 · 计算机科学 2013-04-08 Harold P. Lehmann

Studying psychiatric illness has often been limited by difficulties in connecting symptoms and behavior to neurobiology. Computational psychiatry approaches promise to bridge this gap by providing formal accounts of the latent information…

Capturing the structure of a population and characterising contacts within the population are key to reliable projections of infectious disease. Two main elements of population structure -- contact heterogeneity and age -- have been…

物理与社会 · 物理学 2025-03-17 Luke Murray Kearney , Emma L. Davis , Matt J. Keeling

We have built a computational model for individual aging trajectories of health and survival, which contains physical, functional, and biological variables, and is conditioned on demographic, lifestyle, and medical background information.…

定量方法 · 定量生物学 2022-02-09 Spencer Farrell , Arnold Mitnitski , Kenneth Rockwood , Andrew Rutenberg

The significant increase in the number of individuals with chronic ailments (including the elderly and disabled) has dictated an urgent need for an innovative model for healthcare systems. The evolved model will be more personalized and…

计算机与社会 · 计算机科学 2021-07-09 Mahmoud Nasr , MD. Milon Islam , Shady Shehata , Fakhri Karray , Yuri Quintana

Human beings rely heavily on estimation of poses in order to access their body movements. Human pose estimation methods take advantage of computer vision advances in order to track human body movements in real life applications. This comes…

计算机视觉与模式识别 · 计算机科学 2025-06-05 Arindam Chaudhuri

Medical investigations focusing on patient survival often generate not only a failure time for each patient but also a sequence of measurements on patient health at annual or semi-annual check-ups while the patient remains alive. Such a…

统计方法学 · 统计学 2016-01-18 Peter McCullagh , Walter Dempsey

Managing health lays the core foundation to enabling quality life experiences. Modern computer science research, and especially the field of recommender systems, has enhanced the quality of experiences in fields such as entertainment,…

计算机与社会 · 计算机科学 2018-08-21 Nitish Nag , Mathias Lux , Ramesh C. Jain

Personalized models are essential in digital health because individuals exhibit substantial physiological and behavioral heterogeneity. Yet personalization is limited by scarce and noisy user-specific data. Most existing methods rely on…

人工智能 · 计算机科学 2026-05-15 Zhongqi Yang , Mahkameh Rasouli , Neda Mohseni , Yong Huang , Iman Azimi , Amir M. Rahmani

As we gain access to a greater depth and range of health-related information about individuals, three questions arise: (1) Can we build better models to predict individual-level risk of ill health? (2) How much data do we need to…

机器学习 · 统计学 2021-04-27 Mark Green

Knowing the state of our health at every moment in time is critical for advances in health science. Using data obtained outside an episodic clinical setting is the first step towards building a continuous health estimation system. In this…

人机交互 · 计算机科学 2020-06-24 Vaibhav Pandey , Nitish Nag , Ramesh Jain

The digital twin concept represents an appealing opportunity to advance condition-based and predictive maintenance paradigms for civil engineering systems, thus allowing reduced lifecycle costs, increased system safety, and increased system…

数值分析 · 数学 2023-11-10 Matteo Torzoni , Marco Tezzele , Stefano Mariani , Andrea Manzoni , Karen E. Willcox

Electronic health records (EHR's) are only a first step in capturing and utilizing health-related data - the problem is turning that data into useful information. Models produced via data mining and predictive analysis profile inherited…

数据库 · 计算机科学 2011-12-08 Casey Bennett , Thomas Doub

In the last decades, the interest to understand the connection between brain and body has grown notably. For example, in psychoneuroimmunology many studies associate stress, arising from many different sources and situations, to changes in…

定量方法 · 定量生物学 2022-07-27 Maria Elena Gonzalez Herrero , Christian Kuehn

Health monitoring systems have revolutionized modern healthcare by enabling the continuous capture of physiological and behavioral data, essential for preventive measures and early health intervention. While integrating this data with Large…

机器学习 · 计算机科学 2024-06-26 Ajan Subramanian , Zhongqi Yang , Iman Azimi , Amir M. Rahmani

Modern longitudinal data, for example from wearable devices, measures biological signals on a fixed set of participants at a diverging number of time points. Traditional statistical methods are not equipped to handle the computational…

统计方法学 · 统计学 2023-03-23 Lan Luo , Jingshen Wang , Emily C. Hector

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

组织与器官 · 定量生物学 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Personalized longitudinal disease assessment is central to quickly diagnosing, appropriately managing, and optimally adapting the therapeutic strategy of multiple sclerosis (MS). It is also important for identifying the idiosyncratic…