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The plasticity of amorphous solids undergoing shear is characterized by quasi-localized rearrangements of particles. While many models of plasticity exist, the precise relationship between plastic dynamics and the structure of a particle's…

软凝聚态物质 · 物理学 2024-06-12 Jason W. Rocks , Sean A. Ridout , Andrea J. Liu

A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells. Typical models of cell growth for…

组织与器官 · 定量生物学 2018-05-01 Andrew L. Krause , Dmitry Beliaev , Robert A. Van Gorder , Sarah L. Waters

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

软凝聚态物质 · 物理学 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

The Fluid Mosaic Model by Singer & Nicolson proposes that biological membranes consist of a fluid lipid layer into which integral proteins are embedded. The lipid membrane acts as a two-dimensional liquid in which the proteins can diffuse…

生物物理 · 物理学 2025-09-29 Thomas Heimburg

Porous media are ubiquitous in energy storage and conversion, catalysis, biomechanics, hydrogeology, as well as many other fields. These materials possess high surface-to-volume ratios and their complex channels can restrict and guide the…

流体动力学 · 物理学 2025-12-04 Olivier Guévremont , Lucka Barbeau , Vaiana Moreau , Federico Galli , Nick Virgilio , Bruno Blais

Microstructural models of soft tissue deformation are important in applications including artificial tissue design and surgical planning. The basis of these models, and their advantage over their phenomenological counterparts, is that they…

生物物理 · 物理学 2022-05-06 James Haughton , Simon L. Cotter , William J. Parnell , Tom Shearer

We present benchmark computations of dynamic poroelasticity modeling fluid flow in deformable porous media by a coupled hyperbolic-parabolic system of partial differential equations. A challenging benchmark setting and goal quantities of…

数值分析 · 数学 2023-07-06 Mathias Anselmann , Markus Bause , Nils Margenberg , Pavel Shamko

Swimming microorganisms often self propel in fluids with complex rheology. While past theoretical work indicates that fluid viscoelasticity should hinder their locomotion, recent experiments on waving swimmers suggest a possible…

生物物理 · 物理学 2014-11-25 Emily E. Riley , Eric Lauga

We investigate the problem of transport of a single fluid droplet through a non-wettable superhydrophobic porous medium. A mechanical soft body model is developed and used to simulate the process of pushing fluid droplets through pore space…

计算物理 · 物理学 2020-05-01 Maciej Matyka

Two phase solid-fluid mixture models are ubiquitous in biological applications. For instance, models for growth of tissues and biofilms combine time dependent and quasi-stationary boundary value problems set in domains whose boundary moves…

偏微分方程分析 · 数学 2024-01-17 Ana Carpio , Gema Duro

We develop a mixed finite element method for the coupled problem arising in the interaction between a free fluid governed by the Stokes equations and flow in deformable porous medium modeled by the Biot system of poroelasticity. Mass…

数值分析 · 数学 2021-12-16 Tongtong Li , Ivan Yotov

In a string of recent papers starting with (Transport in Porous Media, 125, 565 (2018)), a theory of immiscible two-phase flow in porous media based on Euler homogeneity of the total volumetric flow rate has been investigated. The…

流体动力学 · 物理学 2025-02-10 Håkon Pedersen

This paper is dedicated to the study of the orthogonal decomposition of spatially and temporally distributed signals in fluid-structure interaction problems. First application is concerned with the analysis of wall-pressure distributions…

流体动力学 · 物理学 2024-01-09 P. Hémon , F. Santi

Research on human skin anatomy reveals its complex multi-scale, multi-phase nature, with up to 70% of its composition being bounded and free water. Fluid movement plays a key role in the skin's mechanical and biological responses,…

We consider a poromechanics model including frictionless contact mechanics. The resulting model consists of the Biot equations with contact boundary conditions leading to a variational inequality modelling mechanical deformations coupled to…

数值分析 · 数学 2024-07-19 Tameem Almani , Kundan Kumar

A new class of micromechanically motivated chain network models for soft biological tissues is presented. On the microlevel, it is based on the statistics of long chain molecules. A wormlike chain model is applied to capture the behavior of…

定量方法 · 定量生物学 2009-11-10 E. Kuhl , K. Garikipati , E. M. Arruda , K. Grosh

The physics of membranes, a classic subject, acquires new momentum from two-dimensional (2D) materials multilayers. This work reports the surprising results emerged during a theoretical study of equilibrium geometry of bilayers as…

介观与纳米尺度物理 · 物理学 2024-12-03 Jin Wang , Erio Tosatti

Biomembranes consisting of two opposing phospholipid monolayers, which comprise the so-called lipid bilayer, are largely responsible for the dual solid-fluid behavior of individual cells and viruses. Quantifying the mechanical…

生物物理 · 物理学 2024-05-27 Naoki Takeishi , Masaya Santo , Naoto Yokoyama , Shigeo Wada

We consider a multiscale approach based on immersed methods for the efficient computational modeling of tissues composed of an elastic matrix (in two or three-dimensions) and a thin vascular structure (treated as a co-dimension two…

数值分析 · 数学 2021-11-18 Luca Heltai , Alfonso Caiazzo

In an idealized way, some turbulent flows can be pictured by assemblies of many vortices characterized by a set of particle distribution functions. Ultrasound provide an useful, nonintrusive, tool to study the spatial structure of vorticity…

chao-dyn · 物理学 2009-10-31 Denis Boyer , Fernando Lund
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