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Neuroblastoma is a strongly heterogeneous cancer with very diverse clinical courses that may vary from spontaneous regression to fatal progression; an accurate patient's risk estimation at diagnosis is essential to design appropriate tumor…

定量方法 · 定量生物学 2018-02-23 Valerio Maggio , Marco Chierici , Giuseppe Jurman , Cesare Furlanello

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

To develop an automated workflow for rectal cancer three-dimensional conformal radiotherapy treatment planning that combines deep-learning(DL) aperture predictions and forward-planning algorithms. We designed an algorithm to automate the…

Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…

图像与视频处理 · 电气工程与系统科学 2025-05-22 Abdul Samad Shaik , Shashaank Mattur Aswatha , Rahul Jashvantbhai Pandya

Several deep learning algorithms have been developed to predict survival of cancer patients using whole slide images (WSIs).However, identification of image phenotypes within the WSIs that are relevant to patient survival and disease…

图像与视频处理 · 电气工程与系统科学 2022-11-30 Xingyu Li , Jitendra Jonnagaddala , Min Cen , Hong Zhang , Xu Steven Xu

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Purpose: To develop a machine learning-based, 3D dose prediction methodology for Gamma Knife (GK) radiosurgery. The methodology accounts for cases involving targets of any number, size, and shape. Methods: Data from 322 GK treatment plans…

医学物理 · 物理学 2023-01-09 Binghao Zhang , Aaron Babier , Timothy C. Y. Chan , Mark Ruschin

Accurate evaluation of the response of glioblastoma to therapy is crucial for clinical decision-making and patient management. The Response Assessment in Neuro-Oncology (RANO) criteria provide a standardized framework to assess patients'…

计算机视觉与模式识别 · 计算机科学 2025-09-09 Daniil Tikhonov , Matheus Scatolin , Mohor Banerjee , Qiankun Ji , Ahmed Jaheen , Mostafa Salem , Abdelrahman Elsayed , Hu Wang , Sarim Hashmi , Mohammad Yaqub

Predicting the infiltration of Glioblastoma (GBM) from medical MRI scans is crucial for understanding tumor growth dynamics and designing personalized radiotherapy treatment plans.Mathematical models of GBM growth can complement the data in…

机器学习 · 计算机科学 2024-08-19 Ray Zirui Zhang , Ivan Ezhov , Michal Balcerak , Andy Zhu , Benedikt Wiestler , Bjoern Menze , John S. Lowengrub

Early detection of brain tumors through magnetic resonance imaging (MRI) is essential for timely treatment, yet access to diagnostic facilities remains limited in remote areas. Gliomas, the most common primary brain tumors, arise from the…

图像与视频处理 · 电气工程与系统科学 2024-12-11 Khush Mendiratta , Shweta Singh , Pratik Chattopadhyay

Automatic segmentation is essential for the brain tumor diagnosis, disease prognosis, and follow-up therapy of patients with gliomas. Still, accurate detection of gliomas and their sub-regions in multimodal MRI is very challenging due to…

图像与视频处理 · 电气工程与系统科学 2022-12-20 Ramy A. Zeineldin , Mohamed E. Karar , Oliver Burgert , Franziska Mathis-Ullrich

Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Valentin Biller , Niklas Bubeck , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Anke Meyer-Baese , Daniel Rückert , Benedikt Wiestler , Jonas Weidner

Glioblastoma multiforme (GBM) is a fast-growing and highly invasive brain tumour, it tends to occur in adults between the ages of 45 and 70 and it accounts for 52 percent of all primary brain tumours. Usually, GBMs are detected by magnetic…

图像与视频处理 · 电气工程与系统科学 2020-04-21 Matteo Rucco , Lorenzo Falsetti , Giovanna Viticchi

Lesion segmentation is a crucial step of the radiomic workflow. Manual segmentation requires long execution time and is prone to variability, impairing the realisation of radiomic studies and their robustness. In this study, a deep-learning…

Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

A brain tumor, whether benign or malignant, can potentially be life threatening and requires painstaking efforts in order to identify the type, origin and location, let alone cure one. Manual segmentation by medical specialists can be…

图像与视频处理 · 电气工程与系统科学 2023-05-02 Ayan Gupta , Mayank Dixit , Vipul Kumar Mishra , Attulya Singh , Atul Dayal

With nearly one million new cases diagnosed worldwide in 2020, head \& neck cancer is a deadly and common malignity. There are challenges to decision making and treatment of such cancer, due to lesions in multiple locations and outcome…

图像与视频处理 · 电气工程与系统科学 2023-05-17 Angel Victor Juanco Muller , Joao F. C. Mota , Keith A. Goatman , Corne Hoogendoorn

Glioma is a common malignant brain tumor with distinct survival among patients. The isocitrate dehydrogenase (IDH) gene mutation provides critical diagnostic and prognostic value for glioma. It is of crucial significance to non-invasively…

图像与视频处理 · 电气工程与系统科学 2021-09-13 Yiran Wei , Yonghao Li , Xi Chen , Carola-Bibiane Schönlieb , Chao Li , Stephen J. Price

Melanoma is a prevalent lethal type of cancer that is treatable if diagnosed at early stages of development. Skin lesions are a typical indicator for diagnosing melanoma but they often led to delayed diagnosis due to high similarities of…

机器学习 · 计算机科学 2023-03-28 Ruitong Sun , Mohammad Rostami

Melanoma, one of most dangerous types of skin cancer, re-sults in a very high mortality rate. Early detection and resection are two key points for a successful cure. Recent research has used artificial intelligence to classify melanoma and…

计算机视觉与模式识别 · 计算机科学 2020-08-31 Cong Tri Pham , Mai Chi Luong , Dung Van Hoang , Antoine Doucet