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Cancer histology reveals disease progression and associated molecular processes, and contains rich phenotypic information that is predictive of outcome. In this paper, we developed a computational approach based on deep learning to predict…

图像与视频处理 · 电气工程与系统科学 2019-09-20 Saima Rathore , Muhammad Aksam Iftikhar , Zissimos Mourelatos

In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…

图像与视频处理 · 电气工程与系统科学 2019-11-20 Mehdi Amian , Mohammadreza Soltaninejad

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

医学物理 · 物理学 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Background: This research aims to improve glioblastoma survival prediction by integrating MR images, clinical and molecular-pathologic data in a transformer-based deep learning model, addressing data heterogeneity and performance…

In this paper, we use a fully convolutional neural network (FCNN) for the segmentation of gliomas from Magnetic Resonance Images (MRI). A fully automatic, voxel based classification was achieved by training a 23 layer deep FCNN on 2-D…

计算机视觉与模式识别 · 计算机科学 2017-12-07 Varghese Alex , Mohammed Safwan , Ganapathy Krishnamurthi

Convolutional neural networks have achieved excellent results in automatic medical image segmentation. In this study, we proposed a novel 3D multi-path DenseNet for generating the accurate glioblastoma (GBM) tumor contour from four…

医学物理 · 物理学 2021-02-25 Jie Fu , Kamal Singhrao , X. Sharon Qi , Yingli Yang , Dan Ruan , John H. Lewis

Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

This paper proposes to use deep radiomic features (DRFs) from a convolutional neural network (CNN) to model fine-grained texture signatures in the radiomic analysis of recurrent glioblastoma (rGBM). We use DRFs to predict survival of rGBM…

计算机视觉与模式识别 · 计算机科学 2019-11-18 Ahmad Chaddad , Saima Rathore , Mingli Zhang , Christian Desrosiers , Tamim Niazi

Accurate prognosis for Glioblastoma (GBM) using deep learning (DL) is hindered by extreme spatial and structural heterogeneity. Moreover, inconsistent MRI acquisition protocols across institutions hinder generalizability of models.…

机器学习 · 计算机科学 2026-02-13 Ankita Paul , Wenyi Wang

Survival prediction models can potentially be used to guide treatment of glioblastoma patients. However, currently available MR imaging biomarkers holding prognostic information are often challenging to interpret, have difficulties…

图像与视频处理 · 电气工程与系统科学 2021-09-28 Sveinn Pálsson , Stefano Cerri , Hans Skovgaard Poulsen , Thomas Urup , Ian Law , Koen Van Leemput

Knowledge of molecular subtypes of gliomas can provide valuable information for tailored therapies. This study aimed to investigate the use of deep convolutional neural networks (DCNNs) for noninvasive glioma subtyping with radiological…

图像与视频处理 · 电气工程与系统科学 2022-03-14 Dong Wei , Yiming Li , Yinyan Wang , Tianyi Qian , Yefeng Zheng

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

Gliomas are lethal type of central nervous system tumors with a poor prognosis. Recently, with the advancements in the micro-array technologies thousands of gene expression related data of glioma patients are acquired, leading for salient…

基因组学 · 定量生物学 2020-11-03 Navodini Wijethilake , Dulani Meedeniya , Charith Chitraranjan , Indika Perera

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…

图像与视频处理 · 电气工程与系统科学 2019-08-08 Milan Decuyper , Roel Van Holen

Segmentation of brain tumor from magnetic resonance imaging (MRI) is a vital process to improve diagnosis, treatment planning and to study the difference between subjects with tumor and healthy subjects. In this paper, we exploit a…

图像与视频处理 · 电气工程与系统科学 2021-04-05 Mobarakol Islam , V Jeya Maria Jose , Hongliang Ren

Glioblastomas are the most aggressive type of glioma, having a 5-year survival rate of 6.9%. Treatment typically involves surgery, followed by radiotherapy and chemotherapy, and frequent magnetic resonance imaging (MRI) scans to monitor…

图像与视频处理 · 电气工程与系统科学 2025-06-05 Ana Matoso , Catarina Passarinho , Marta P. Loureiro , José Maria Moreira , Patrícia Figueiredo , Rita G. Nunes

Radiomics has shown a capability for different types of cancers such as glioma to predict the clinical outcome. It can have a non-invasive means of evaluating the immunotherapy response prior to treatment. However, the use of deep…

图像与视频处理 · 电气工程与系统科学 2022-06-07 Ahmad Chaddad , Mingli Zhang , Lama Hassan , Tamim Niazi

Imaging biomarkers offer a non-invasive way to predict the response of immunotherapy prior to treatment. In this work, we propose a novel type of deep radiomic features (DRFs) computed from a convolutional neural network (CNN), which…

计算机视觉与模式识别 · 计算机科学 2022-06-10 Ahmad Chaddad , Paul Daniel Mingli Zhang , Saima Rathore , Paul Sargos , Christian Desrosiers , Tamim Niazi
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