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Differentiating tumor progression (TP) from treatment-related necrosis (TN) is critical for clinical management decisions in glioblastoma (GBM). Dynamic FDG PET (dPET), an advance from traditional static FDG PET, may prove advantageous in…

图像与视频处理 · 电气工程与系统科学 2023-03-01 Tonmoy Hossain , Zoraiz Qureshi , Nivetha Jayakumar , Thomas Eluvathingal Muttikkal , Sohil Patel , David Schiff , Miaomiao Zhang , Bijoy Kundu

In this work, we aim to predict the survival time (ST) of glioblastoma (GBM) patients undergoing different treatments based on preoperative magnetic resonance (MR) scans. The personalized and precise treatment planning can be achieved by…

计算机视觉与模式识别 · 计算机科学 2024-02-13 Xiaofeng Liu , Nadya Shusharina , Helen A Shih , C. -C. Jay Kuo , Georges El Fakhri , Jonghye Woo

Recent analysis identified distinct genomic subtypes of lower-grade glioma tumors which are associated with shape features. In this study, we propose a fully automatic way to quantify tumor imaging characteristics using deep learning-based…

图像与视频处理 · 电气工程与系统科学 2019-06-11 Mateusz Buda , Ashirbani Saha , Maciej A Mazurowski

Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery…

图像与视频处理 · 电气工程与系统科学 2020-09-08 Sobia Yousaf , Syed Muhammad Anwar , Harish RaviPrakash , Ulas Bagci

Glioblastoma Multiforme (GBM) is a malignant brain cancer forming around 48% of al brain and Central Nervous System (CNS) cancers. It is estimated that annually over 13,000 deaths occur in the US due to GBM, making it crucial to have early…

图像与视频处理 · 电气工程与系统科学 2022-01-28 Sauman Das

With the rise in importance of personalized medicine, we trained personalized neural networks to detect tumor progression in longitudinal datasets. The model was evaluated on two datasets with a total of 64 scans from 32 patients diagnosed…

机器学习 · 计算机科学 2022-10-28 Christian Strack , Kelsey L. Pomykala , Heinz-Peter Schlemmer , Jan Egger , Jens Kleesiek

Glioblastoma is one of the most aggressive and common brain tumors, with a median survival of 10-15 months. Predicting Overall Survival (OS) is critical for personalizing treatment strategies and aligning clinical decisions with patient…

计算机视觉与模式识别 · 计算机科学 2025-12-17 Yin Lin , Riccardo Barbieri , Domenico Aquino , Giuseppe Lauria , Marina Grisoli , Elena De Momi , Alberto Redaelli , Simona Ferrante

Detecting and segmenting brain metastases is a tedious and time-consuming task for many radiologists, particularly with the growing use of multi-sequence 3D imaging. This study demonstrates automated detection and segmentation of brain…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Endre Grøvik , Darvin Yi , Michael Iv , Elisabeth Tong , Daniel L. Rubin , Greg Zaharchuk

Colorectal cancer liver metastasis (CRLM) exhibits high postoperative recurrence and pronounced prognostic heterogeneity, challenging individualized management. Existing prognostic approaches often rely on static representations from a…

图像与视频处理 · 电气工程与系统科学 2026-04-09 Wei Yang , Yiran Zhu , Yan su , Zesheng Li , Chengchang Pan , Honggang Qi

Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

机器学习 · 计算机科学 2026-01-13 Hasan M Jamil

Gliomas are the most common primary tumors of the central nervous system. Multimodal MRI is widely used for the preliminary screening of gliomas and plays a crucial role in auxiliary diagnosis, therapeutic efficacy, and prognostic…

图像与视频处理 · 电气工程与系统科学 2025-05-27 Yihao Liu , Zhihao Cui , Liming Li , Junjie You , Xinle Feng , Jianxin Wang , Xiangyu Wang , Qing Liu , Minghua Wu

Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Inspired by the success of Convolutional Neural Networks (CNN), we develop a novel Computer Aided Detection (CADe) system using CNN for Glioblastoma Multiforme (GBM) detection and segmentation from multi channel MRI data. A two-stage…

计算机视觉与模式识别 · 计算机科学 2018-06-21 Subhasis Banerjee , Sushmita Mitra , Anmol Sharma , B. Uma Shankar

Tumor segmentation is a fundamental step for radiotherapy treatment planning. To define an accurate segmentation of the primary tumor (GTVp) of oropharyngeal cancer patients (OPC), simultaneous assessment of different image modalities is…

图像与视频处理 · 电气工程与系统科学 2023-03-08 Alessia De Biase , Nanna Maria Sijtsema , Lisanne van Dijk , Johannes A. Langendijk , Peter van Ooijen

Glioblastoma Multiforme is a very aggressive type of brain tumor. Due to spatial and temporal intra-tissue inhomogeneity, location and the extent of the cancer tissue, it is difficult to detect and dissect the tumor regions. In this paper,…

图像与视频处理 · 电气工程与系统科学 2021-01-27 Snehal Rajput , Rupal Agravat , Mohendra Roy , Mehul S Raval

Radiomic features achieve promising results in cancer diagnosis, treatment response prediction, and survival prediction. Our goal is to compare the handcrafted (explicitly designed) and deep learning (DL)-based radiomic features extracted…

Purpose Tumor-infiltrating lymphocytes (TILs) have significant prognostic values in cancers. However, very few automated, deep-learning-based TIL scoring algorithms have been developed for colorectal cancers (CRC). Methods We developed an…

定量方法 · 定量生物学 2022-09-16 Anran Liu , Xingyu Li , Hongyi Wu , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Glioblastoma recurrence is largely driven by diffuse infiltration beyond radiologically visible tumor margins, yet standard radiotherapy, the mainstay of glioblastoma treatment, relies on uniform expansions that ignore patient-specific…

图像与视频处理 · 电气工程与系统科学 2026-03-17 L. Zimmer , J. Weidner , M. Balcerak , F. Kofler , M. Krupa , I. Ezhov , S. Cepeda , R. Zhang , J. Lowengrub , B. Menze , B. Wiestler

Objectives We aimed to evaluate the diagnostic performance of deep learning (DL)-based radiomics models for the noninvasive prediction of isocitrate dehydrogenase (IDH) mutation and 1p/19q co-deletion status in glioma patients using MRI…

定量方法 · 定量生物学 2025-08-19 Somayeh Farahani , Marjaneh Hejazi , Mehnaz Tabassum , Antonio Di Ieva , Neda Mahdavifar , Sidong Liu