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A number of strange results have been reported for the twist elasticity of a semiflexible filament, actin. In particular dynamic and static methods for determining the torsional twist modulus give very different results. I show here that…

软凝聚态物质 · 物理学 2007-05-23 A. C. Maggs

The process by which one may take a discrete model of a biophysical process and construct a continuous model based on it is of mathematical interest as well as being of practical use. In this paper, we first study the singular limit of a…

偏微分方程分析 · 数学 2019-01-01 Lianzhang Bao , Zhengfang Zhou

The step motions considered are those in which crystallization is controlled by a single diffusion process, either the substance diffusion for growth from solution or the flow of latent heat from the step for growth from melt. Quasi-static…

凝聚态物理 · 物理学 2009-10-22 Serge Yu. Potapenko

We present a simple and generic theoretical description of actin-based motility, where polymerization of filaments maintains propulsion. The dynamics is driven by polymerization kinetics at the filaments' free ends, crosslinking of the…

细胞行为 · 定量生物学 2015-05-13 Azam Gholami , Martin Falcke , Erwin Frey

The approach of nonequilibrium evolution thermodynamics earlier offered is developed. It helps to describe the processes of defect formation within the adiabatic approximation. The basic equations system depends on the initial defects…

材料科学 · 物理学 2015-10-23 A. V. Khomenko , D. S. Troshchenko , L. S. Metlov

The intermittent transition between slow growth and rapid shrinkage in polymeric assemblies is termed dynamic instability, a feature observed in a variety of biochemically distinct assemblies including microtubules, actin and their…

软凝聚态物质 · 物理学 2015-05-28 Stefano Zapperi , L. Mahadevan

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

软凝聚态物质 · 物理学 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

Inside cells of living organisms, actin filaments and microtubules self-assemble and dissemble dynamically by incorporating actin or tubulin from the cell plasma or releasing it into their tips' surroundings. Such reaction-diffusion systems…

生物物理 · 物理学 2019-09-04 Johannes Pausch , Gunnar Pruessner

Achieving control and tunability of lyotropic materials has been a long-standing goal of liquid crystal research. Here we show that the elasticity of a liquid crystal system consisting of a dense suspension of semiflexible biopolymers can…

软凝聚态物质 · 物理学 2018-01-12 Rui Zhang , Nitin Kumar , Jennifer Ross , Margaret L. Gardel , Juan J. de Pablo

In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the behavior of synthetic or living active matter. Great progress…

软凝聚态物质 · 物理学 2025-08-29 Q. Martinet , Y. Li , A. Aubret , E. Hannezo , J. Palacci

We present a statistical mechanical study of stiff polymers, motivated by experiments on actin filaments and the considerable current interest in polymer networks. We obtain simple, approximate analytical forms for the force-extension…

软凝聚态物质 · 物理学 2009-11-13 Abhijit Ghosh , Joseph Samuel , Supurna Sinha

Step meandering instability in a Burton-Cabrera-Frank (BCF)-type model for the growth of an isolated, atomically high step on a crystal surface is analyzed. It is assumed that the growth is sustained by the molecular precursors deposition…

材料科学 · 物理学 2015-06-18 Mikhail Khenner

The dynamic behavior of bundles of actin filaments growing against a loaded obstacle is investigated through a generalized version of the standard multi filaments Brownian Ratchet model in which the (de)polymerizing filaments are treated…

生物物理 · 物理学 2019-05-22 Alessia Perilli , Carlo Pierleoni , Jean-Paul Ryckaert

We consider a beam model representing the transverse deflections of a one dimensional elastic structure immersed in an axial fluid flow. The model includes a nonlinear elastic restoring force, with damping and non-conservative terms…

偏微分方程分析 · 数学 2019-04-22 Jason Howell , Katelynn Huneycutt , Justin T. Webster , Spencer Wilder

Based on experimental observations it is known that various biological cells exhibit a persistent random walk during migration on flat substrates. The persistent random walk is characterized by `stop-and-go' movements : unidirectional…

亚细胞过程 · 定量生物学 2009-11-11 B. Nandy , A. Baumgaertner

We establish the Statistical Mechanics framework for a bundle of Nf living and uncrosslinked actin filaments in a supercritical solution of free monomers pressing against a mobile wall. The filaments are anchored normally to a fixed planar…

生物物理 · 物理学 2016-07-27 Alessia Perilli , Carlo Pierleoni , Giovanni Ciccotti , Jean Paul Ryckaert

Migration of animal cells is based on the interplay between actin polymerization at the front, adhesion along the cell-substrate interface, and actomyosin contractility at the back. Active gel theory has been used before to demonstrate that…

细胞行为 · 定量生物学 2024-12-11 Valentin Wössner , Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

Modeling the spontaneous evolution of morphology in natural systems and its preservation by proportionate growth remains a major scientific challenge. Yet, it is conceivable that if the basic mechanisms of growth and the coupled kinetic…

软凝聚态物质 · 物理学 2020-12-30 Virginia von Streng , Rami Abi-Akl , Bianca Giovanardi , Tal Cohen

We propose a variational framework for accretive surface growth driven by an optimality principle. Rather than prescribing a kinetic law, the configuration at each time step is obtained, within a time-discrete setting, as the solution of a…

数学物理 · 物理学 2026-05-14 Rohan Abeyaratne , Roberto Paroni , Marco Picchi Scardaoni

Developing tissues need to pattern themselves in space and time. A prevalent mechanism to achieve this are pulsatile active stresses generated by the actin cytoskeleton. Active gel theory is a powerful tool to model the dynamics of…

生物物理 · 物理学 2023-02-21 Eloy Merlijn de Kinkelder , Elisabeth Fischer-Friedrich , Sebastian Aland