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We explore efficient estimation of statistical quantities, particularly rare event probabilities, for stochastic reaction networks. Consequently, we propose an importance sampling (IS) approach to improve the Monte Carlo (MC) estimator…

数值分析 · 数学 2024-03-12 Chiheb Ben Hammouda , Nadhir Ben Rached , Raúl Tempone , Sophia Wiechert

This work presents an efficient approach for accelerating multilevel Markov Chain Monte Carlo (MCMC) sampling for large-scale problems using low-fidelity machine learning models. While conventional techniques for large-scale Bayesian…

机器学习 · 统计学 2024-05-21 Sohail Reddy , Hillary Fairbanks

We show how to extend a recently proposed multi-level Monte Carlo approach to the continuous time Markov chain setting, thereby greatly lowering the computational complexity needed to compute expected values of functions of the state of the…

概率论 · 数学 2011-11-23 David F. Anderson , Desmond J. Higham

Monte Carlo methods represent the "de facto" standard for approximating complicated integrals involving multidimensional target distributions. In order to generate random realizations from the target distribution, Monte Carlo techniques use…

统计计算 · 统计学 2022-01-21 L. Martino , V. Elvira , D. Luengo , J. Corander

This work combines multilevel Monte Carlo (MLMC) with importance sampling to estimate rare-event quantities that can be expressed as the expectation of a Lipschitz observable of the solution to a broad class of McKean--Vlasov stochastic…

We consider the efficient use of an approximation within Markov chain Monte Carlo (MCMC), with subsequent importance sampling (IS) correction of the Markov chain inexact output, leading to asymptotically exact inference. We detail…

统计计算 · 统计学 2019-04-15 Jordan Franks

Statistical signal processing applications usually require the estimation of some parameters of interest given a set of observed data. These estimates are typically obtained either by solving a multi-variate optimization problem, as in the…

统计计算 · 统计学 2021-07-27 D. Luengo , L. Martino , M. Bugallo , V. Elvira , S. Särkkä

Nested Monte Carlo is widely used for risk estimation, but its efficiency is limited by the discontinuity of the indicator function and high computational cost. This paper proposes a nested Multilevel Monte Carlo (MLMC) method combined with…

数值分析 · 数学 2026-04-06 Yu Xu , Xiaoqun Wang

Discrete-state, continuous-time Markov models are becoming commonplace in the modelling of biochemical processes. The mathematical formulations that such models lead to are opaque, and, due to their complexity, are often considered…

定量方法 · 定量生物学 2017-10-31 Christopher Lester

Monte Carlo simulations of quantum field theories on a lattice become increasingly expensive as the continuum limit is approached since the cost per independent sample grows with a high power of the inverse lattice spacing. Simulations on…

高能物理 - 格点 · 物理学 2021-01-04 Karl Jansen , Eike Hermann Müller , Robert Scheichl

In this article we develop a multi-grid multi-level Monte Carlo (MGMLMC) method for the stochastic Stokes-Darcy interface model with random hydraulic conductivity both in the porous media domain and on the interface. Because the randomness…

数值分析 · 数学 2019-03-07 Zhipeng Yang , Xiaoming He , Li Zhang , Ju Ming

In many real-world engineering systems, the performance or reliability of the system is characterised by a scalar parameter. The distribution of this performance parameter is important in many uncertainty quantification problems, ranging…

统计方法学 · 统计学 2022-10-03 Robert Millar , Jinglai Li , Hui Li

In this work, we present, analyze, and implement a class of Multi-Level Markov chain Monte Carlo (ML-MCMC) algorithms based on independent Metropolis-Hastings proposals for Bayesian inverse problems. In this context, the likelihood function…

数值分析 · 数学 2021-05-06 Juan Pablo Madrigal-Cianci , Fabio Nobile , Raul Tempone

We propose a hierarchy of multi-level kinetic Monte Carlo methods for sampling high-dimensional, stochastic lattice particle dynamics with complex interactions. The method is based on the efficient coupling of different spatial resolution…

数值分析 · 数学 2012-08-06 Evangelia Kalligiannaki , Markos A. Katsoulakis , Petr Plechac

We propose a novel alternative approach to our previous work (Ben Hammouda et al., 2023) to improve the efficiency of Monte Carlo (MC) estimators for rare event probabilities for stochastic reaction networks (SRNs). In the same spirit of…

数值分析 · 数学 2024-03-12 Chiheb Ben Hammouda , Nadhir Ben Rached , Raúl Tempone , Sophia Wiechert

Atomistic simulations provide valuable insights into the physical processes governing material behavior. However, their applicability is fundamentally constrained by the limited time scales accessible to brute-force simulations. This…

计算物理 · 物理学 2026-02-16 Michael Kim , Wei Cai

In this paper we address the problem of Monte Carlo approximation of posterior probability distributions in stochastic kinetic models (SKMs). SKMs are multivariate Markov jump processes that model the interactions among species in…

统计方法学 · 统计学 2014-04-22 Eugenia Koblents , Joaquín Míguez

We study statistical model checking of continuous-time stochastic hybrid systems. The challenge in applying statistical model checking to these systems is that one cannot simulate such systems exactly. We employ the multilevel Monte Carlo…

系统与控制 · 计算机科学 2017-06-27 Sadegh Esmaeil Zadeh Soudjani , Rupak Majumdar , Tigran Nagapetyan

In this paper, we evaluate the performance of the multilevel Monte Carlo method (MLMC) for deterministic and uncertain hyperbolic systems, where randomness is introduced either in the modeling parameters or in the approximation algorithms.…

数值分析 · 数学 2023-01-04 Junpeng Hu , Shi Jin , Jinglai Li , Lei Zhang

In this work, we consider the problem of estimating summary statistics to characterise biochemical reaction networks of interest. Such networks are often described using the framework of the Chemical Master Equation (CME). For…

定量方法 · 定量生物学 2018-11-27 Christopher Lester , Christian A. Yates , Ruth E. Baker
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