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The present paper investigates the extension behavior of a wormlike chain with varied persistence length under the confinement of a cylindrical tube. Based on Odijk theory of a confined polymer chain, we have developed a theory which can…

生物物理 · 物理学 2019-11-05 Ming Li , Jizeng Wang

The sequence-dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base-pair model, whose strains are the relative position and orientation of adjacent base-pairs. Corresponding elastic potentials have…

生物大分子 · 定量生物学 2013-05-29 Nils B. Becker , Ralf Everaers

DNA bending on length scales shorter than a persistence length plays an integral role in the translation of genetic information from DNA to cellular function. Quantitative experimental studies of these biological systems have led to a…

软凝聚态物质 · 物理学 2009-11-11 Paul A. Wiggins , Philip C. Nelson

Synthetic copolymers and biopolymers, such as polypeptides and double-stranded DNA, often exhibit strong variations in bending stiffness along their contour, which can significantly impact conformational behavior at larger scales. To…

软凝聚态物质 · 物理学 2025-11-04 Yannick Witzky , Friederike Schmid , Arash Nikoubashman

The wormlike chain model of stiff polymers is a nonlinear $\sigma$-model in one spacetime dimension in which the ends are fluctuating freely. This causes important differences with respect to the presently available theory which exists only…

软凝聚态物质 · 物理学 2009-11-11 H. Kleinert , A. Chervyakov

We develop a continuum elastic approach to examining the bending mechanics of semiflexible filaments with a local internal degree of freedom that couples to the bending modulus. We apply this model to study the nonlinear mechanics of a…

软凝聚态物质 · 物理学 2013-02-12 Arthur A. Evans , Alex J. Levine

We report a theoretical study of DNA flexibility and quantitatively predict the ring closure probability as a function of DNA contour length. Recent experimental studies show that the flexibility of short DNA fragments (as compared to the…

软凝聚态物质 · 物理学 2013-10-01 Xinliang Xu , Beng Joo Reginald , Jianshu Cao

When the local intrinsic stiffness of a polymer chain varies over a wide range, one can observe both a crossover from rigid-rod-like behavior to (almost) Gaussian random coils and a further crossover towards self-avoiding walks in good…

软凝聚态物质 · 物理学 2015-03-17 Hsiao-Ping Hsu , Wolfgang Paul , Kurt Binder

We demonstrate that a semiflexible bundle of wormlike chains exhibits a state-dependent bending stiffness that alters fundamentally its scaling behavior with respect to the standard wormlike chain. We explore the equilibrium conformational…

统计力学 · 物理学 2007-07-26 Claus Heussinger , Mark Bathe , Erwin Frey

The endpoint distribution and dynamics of semiflexible fibers is studied by numerical simulation. A brief overview is given over the analytical theory of flexible and semiflexible polymers. In particular, a closed expression is given for…

软凝聚态物质 · 物理学 2013-06-13 Robert D. Groot

We derive the stochastic equations of motion for a tracer that is tightly attached to a semiflexible polymer and confined or agitated by an externally controlled potential. The generalised Langevin equation, the power spectrum, and the…

软凝聚态物质 · 物理学 2011-11-22 Jakob Tómas Bullerjahn , Sebastian Sturm , Lars Wolff , Klaus Kroy

Using molecular dynamics simulations we examine the dynamics of a family of model polymers with varying chain length and torsional potential barriers. We focus on features of the dynamics of polymers that are seen experimentally but absent…

软凝聚态物质 · 物理学 2019-06-11 Daniel Fragiadakis , C. Michael Roland

The importance of nonlinearities in material constitutive relations has long been appreciated in the continuum mechanics of macroscopic rods. Although the moment (torque) response to bending is almost universally linear for small deflection…

软凝聚态物质 · 物理学 2009-11-10 Paul A. Wiggins , Rob Phillips , Philip C. Nelson

We study the elastic response of a worm-like polymer chain with reversible kink-like structural defects. This is a generic model for (a) the double-stranded DNA with sharp bends induced by binding of certain proteins, and (b) effects of…

软凝聚态物质 · 物理学 2009-11-10 Yuri O. Popov , Alexei V. Tkachenko

Recent experimental data indicate that the elastic wormlike rod model of DNA that works well on long length scales may break down on shorter scales relevant to biology. According to Noy and Golestanian (Phys. Rev. Lett. 109, 228101, 2012)…

生物大分子 · 定量生物学 2013-11-12 Alexey K. Mazur

The flexibility of short DNA chains is investigated via computation of the average correlation function between dimers which defines the persistence length. Path integration techniques have been applied to confine the phase space available…

软凝聚态物质 · 物理学 2018-10-19 Marco Zoli

We present a phenomenological dynamical model able to describe the stretching features of the curve of DNA length vs applied force. As concerns the chain, the model is based on the discrete wormlike chain model with elastic modifications,…

生物物理 · 物理学 2012-09-25 Alessandro Fiasconaro , Fernando falo

Loop formation between monomers in the interior of semiflexible chains describes elementary events in biomolecular folding and DNA bending. We calculate analytically the interior distance distribution function for semiflexible chains using…

软凝聚态物质 · 物理学 2009-11-11 Changbong Hyeon , D. Thirumalai

A formula is derived for stiffness of a polymer chain in terms of the distribution function of end-to-end vectors. This relationship is applied to calculate the stiffness of Gaussian chains (neutral and carrying electric charges at the…

统计力学 · 物理学 2007-05-23 A. D. Drozdov

Force versus extension curves measure entropic elasticity of single polymer chain in force spectroscopy experiments. A Worm-like Chain model is used to describe force extension experiments with an intrinsic chain parameter called…

软凝聚态物质 · 物理学 2021-07-28 Vikhyaat Ahlawat , Shatruhansingh Rajput , Shivprasad Patil
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