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相关论文: Digital Twin approach to Clinical DSS with Explain…

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A digital health twin can be defined as a virtual model of a physical person, in this specific case, a patient. This virtual model is constituted by multidimensional data that can host from clinical, molecular and therapeutic parameters to…

计算机与社会 · 计算机科学 2022-12-02 Manuel Cossio

With rapid digitization and digitalization, drawing a fine line between the digital and the physical world has become nearly impossible. It has become essential more than ever to integrate all spheres of life into a single Digital Thread to…

The paper presents an approach for building consistent and applicable clinical decision support systems (CDSSs) using a data-driven predictive model aimed at resolving the problem of low applicability and scalability of CDSSs in real-world…

人工智能 · 计算机科学 2022-02-18 Sergey V. Kovalchuk , Georgy D. Kopanitsa , Ilia V. Derevitskii , Daria A. Savitskaya

The objective of personalized medicine is to tailor interventions to an individual patient's unique characteristics. A key technology for this purpose involves medical digital twins, computational models of human biology that can be…

定量方法 · 定量生物学 2024-03-22 Lucas Böttcher , Luis L. Fonseca , Reinhard C. Laubenbacher

With healthcare demand rising worldwide, hospital services are increasingly needed. Hospitals' performance is tightly linked to their surgical suite performance, which makes it necessary for surgical suites to be efficient. In this paper,…

最优化与控制 · 数学 2025-09-04 Leah Rifi , Canan Pehlivan , Cléa Martinez , Maria Di Mascolo , Franck Fontanili

Digital twin (DT) technology holds immense potential for transforming healthcare systems through real-time monitoring, predictive analysis, and agile interventions to support various decision-making needs. However, its successful…

计算机与社会 · 计算机科学 2025-08-05 Md Doulotuzzaman Xames , Taylan G. Topcu

Clinical trials are indispensable for medical research and the development of new treatments. However, clinical trials often involve thousands of participants and can span several years to complete, with a high probability of failure during…

机器学习 · 计算机科学 2024-07-02 Yue Wang , Tianfan Fu , Yinlong Xu , Zihan Ma , Hongxia Xu , Yingzhou Lu , Bang Du , Honghao Gao , Jian Wu

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

统计方法学 · 统计学 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

The design and operation of systems are conventionally viewed as a sequential decision-making process that is informed by data from physical experiments and simulations. However, the integration of these high-dimensional and heterogeneous…

应用统计 · 统计学 2025-03-04 Anton van Beek , Vispi Karkaria , Wei Chen

Deep learning, an area of machine learning, is set to revolutionize patient care. But it is not yet part of standard of care, especially when it comes to individual patient care. In fact, it is unclear to what extent data-driven techniques…

机器学习 · 计算机科学 2019-06-07 Gal Levy-Fix , Gilad J. Kuperman , Noémie Elhadad

Despite the growing use of Electronic Health Records (EHR) for AI-assisted diagnosis prediction, most data-driven models struggle to incorporate clinically meaningful medical knowledge. They often rely on limited ontologies, lacking…

机器学习 · 计算机科学 2025-04-17 Pengfei Hu , Chang Lu , Fei Wang , Yue Ning

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

机器学习 · 计算机科学 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel

Digital twins have attracted a great deal of recent attention from a wide range of fields. A basic requirement for digital twins of nonlinear dynamical systems is the ability to generate the system evolution and predict potentially…

机器学习 · 计算机科学 2023-09-21 Ying-Cheng Lai

Vehicles are complex Cyber Physical Systems (CPS) that operate in a variety of environments, and the likelihood of failure of one or more subsystems, such as the engine, transmission, brakes, and fuel, can result in unscheduled downtime and…

机器学习 · 计算机科学 2023-02-02 Subash Neupane , Ivan A. Fernandez , Wilson Patterson , Sudip Mittal , Milan Parmar , Shahram Rahimi

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

机器学习 · 计算机科学 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

机器学习 · 计算机科学 2026-05-13 Zarrin Monirzadeh

Cognitive Twins (CT) are proposed as Digital Twins (DT) with augmented semantic capabilities for identifying the dynamics of virtual model evolution, promoting the understanding of interrelationships between virtual models and enhancing the…

系统与控制 · 电气工程与系统科学 2020-01-15 Jinzhi Lu , Xiaochen Zheng , Ali Gharaei , Kostas Kalaboukas , Dimitris Kiritsis

Digital twin models are of high interest to Head and Neck Cancer (HNC) oncologists, who have to navigate a series of complex treatment decisions that weigh the efficacy of tumor control against toxicity and mortality risks. Evaluating…

As cannabis use has increased in recent years, researchers have come to rely on sophisticated machine learning models to predict cannabis use behavior and its impact on health. However, many artificial intelligence (AI) models lack…

人机交互 · 计算机科学 2025-03-11 Tongze Zhang , Tammy Chung , Anind Dey , Sang Won Bae

The concept of creating a virtual copy of a complete Cyber-Physical System opens up numerous possibilities, including real-time assessments of the physical environment and continuous learning from the system to provide reliable and precise…

人工智能 · 计算机科学 2023-11-22 Carine Menezes Rebello , Johannes Jäschkea , Idelfonso B. R. Nogueira