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For the simulation of rectilinearly moving conductors across a magnetic field, the Galer-kin finite element method (GFEM) is generally employed. The inherent instability of GFEM is very often addressed by employing Streamline…

数值分析 · 数学 2016-08-22 Sethupathy Subramanian , Udaya Kumar

We present computer-assisted methods for analyzing stochastic models of gene regulatory networks. The main idea that underlies this equation-free analysis is the design and execution of appropriately-initialized short bursts of stochastic…

生物物理 · 物理学 2009-11-11 Radek Erban , Ioannis G. Kevrekidis , David Adalsteinsson , Timothy C. Elston

Here we propose a new approach to modeling gene expression based on the theory of random dynamical systems (RDS) that provides a general coupling prescription between the nodes of any given regulatory network given the dynamics of each node…

分子网络 · 定量生物学 2016-07-11 Fernando Antoneli , Renata C. Ferreira , Marcelo R. S. Briones

Graph Convolutional Network (GCN) has exhibited strong empirical performance in many real-world applications. The vast majority of existing works on GCN primarily focus on the accuracy while ignoring how confident or uncertain a GCN is with…

机器学习 · 计算机科学 2022-10-13 Jian Kang , Qinghai Zhou , Hanghang Tong

A stochastic model predictive control (SMPC) approach is presented for discrete-time linear systems with arbitrary time-invariant probabilistic uncertainties and additive Gaussian process noise. Closed-loop stability of the SMPC approach is…

系统与控制 · 计算机科学 2015-03-17 Joel A. Paulson , Stefan Streif , Ali Mesbah

Gene expression has a stochastic component owing to the single molecule nature of the gene and the small number of copies of individual DNA binding proteins in the cell. We show how the statistics of such systems can be mapped on to quantum…

无序系统与神经网络 · 物理学 2009-11-10 Masaki Sasai , Peter G. Wolynes

We show that noise-induced oscillations in a gene circuit model display stochastic coherence, that is, a maximum in the regularity of the oscillations as a function of noise amplitude. The effect is manifest as a system-size effect in a…

分子网络 · 定量生物学 2009-08-05 Robert C. Hilborn , Jessie D. Erwin

We present an error analysis for the discontinuous Galerkin method applied to the discrete-ordinate discretization of the steady-state radiative transfer equation. Under some mild assumptions, we show that the DG method converges uniformly…

数值分析 · 数学 2020-09-25 Qiwei Sheng , Cory D. Hauck

This paper considers uncertainty quantification in systems perturbed by stochastic disturbances, in particular, Gaussian white noise. The main focus of this work is on describing the time evolution of statistical moments of certain…

系统与控制 · 电气工程与系统科学 2020-07-28 Anant A. Joshi , Kamesh Subbarao

In this paper we address the problem of uncertainty management for robust design, and verification of large dynamic networks whose performance is affected by an equally large number of uncertain parameters. Many such networks (e.g. power,…

统计计算 · 统计学 2011-10-12 Amit Surana , Tuhin Sahai , Andrzej Banaszuk

As an extension of our previous work in Sun et.al (2018) [41], we develop a discontinuous Galerkin method for solving cross-diffusion systems with a formal gradient flow structure. These systems are associated with non-increasing entropy…

数值分析 · 数学 2018-10-09 Zheng Sun , José Antonio Carrillo , Chi-Wang Shu

Engineering biology requires precise control of biomolecular circuits, and Cybergenetics is the field dedicated to achieving this goal. A significant challenge in developing controllers for cellular functions is designing systems that can…

定量方法 · 定量生物学 2024-09-18 Hamza Faquir , Manuel Pájaro , Irene Otero-Muras

This paper addresses the Bayesian calibration of dynamic models with parametric and structural uncertainties, in particular where the uncertain parameters are unknown/poorly known spatio-temporally varying subsystem models. Independent…

统计计算 · 统计学 2012-11-02 Piyush Tagade , Han-Lim Choi

We investigate the stabilization of unstable multidimensional partially observed single-sensor and multi-sensor linear systems driven by unbounded noise and controlled over discrete noiseless channels under fixed-rate information…

最优化与控制 · 数学 2012-09-21 Andrew P. Johnston , Serdar Yüksel

Continuous-time random disturbances (also called stochastic excitations) due to increasing renewable generation have an increasing impact on power system dynamics; However, except from the Monte Carlo simulation, most existing methods for…

最优化与控制 · 数学 2020-07-07 Yiwei Qiu , Jin Lin , Xiaoshuang Chen , Feng Liu , Yonghua Song

Robust optimization is a method for optimization under uncertainties in engineering systems and designs for applications ranging from aeronautics to nuclear. In a robust design process, parameter variability (or uncertainty) is incorporated…

统计计算 · 统计学 2022-10-17 Richa Verma , Dinesh Kumar , Kazuma Kobayashi , Syed Alam

We propose an iterative method to safely learn the unmodeled dynamics of a nonlinear system using Bayesian Gaussian process (GP) models with polynomial kernel functions. The method maintains safety by ensuring that the system state stays…

系统与控制 · 电气工程与系统科学 2020-04-03 Alex Devonport , He Yin , Murat Arcak

In this paper, we derive a novel procedure for set-membership estimation of dynamical systems affected by stochastic noise with unbounded support. Employing a bound on the sample covariance matrix, we are able to provide a finite- sample…

系统与控制 · 电气工程与系统科学 2026-05-20 Felix Brändle , Nicolas Chatzikiriakos , Andrea Iannelli , Frank Allgöwer

We develop a method for reconstructing regulatory interconnection networks between variables evolving according to a linear dynamical system. The work is motivated by the problem of gene regulatory network inference, that is, finding causal…

统计方法学 · 统计学 2018-02-19 Atte Aalto , Jorge Goncalves

Model Predictive Control (MPC) of an unknown system that is modelled by Gaussian Process (GP) techniques is studied in this paper. Using GP, the variances computed during the modelling and inference processes allow us to take model…

系统与控制 · 计算机科学 2016-12-06 Gang Cao , Edmund M-K Lai , Fakhrul Alam